1. [Expression of gamma interferon during HPV and Chlamydia trachomatis infection in cervical samples].
- Author
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Colín-Ferreyra Mdel C, Mendieta-Zerón H, Romero-Figueroa Mdel S, Martínez-Madrigal M, Martínez-Pérez S, and Domínguez-García MV
- Subjects
- Adult, Chlamydia Infections complications, Cross-Sectional Studies, Female, Humans, Papillomavirus Infections complications, Squamous Intraepithelial Lesions of the Cervix complications, Chlamydia Infections metabolism, Chlamydia trachomatis, Interferon-gamma biosynthesis, Papillomavirus Infections metabolism, Squamous Intraepithelial Lesions of the Cervix microbiology
- Abstract
Introduction: The aim of this study was to mesure the expression of gamma interferon in HPV and Chlamydia trachomatis infection in squamous intraepithelial lesions., Method: Samples from 100 patients diagnosed by colposcopy with or without squamous intraepithelial lesions were used in the present study. Each patient was found to be infected by HPV and C.trachomatis. Relative gamma interferon mRNA expression was assessed using a real-time reverse transcriptase PCR assay (RT-PCR)., Results: The relative units of expression of gamma interferon mRNA were 13, 1.8 and 0.3, for HPV and C.trachomatis co-infection, or HPV or C.trachomatis infection, respectively., Conclusion: HPV and C.trachomatis could overstimulate the expression of gamma interferon., (Copyright © 2014 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.)
- Published
- 2015
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