1. Controlled Study of Pre‐ and Postoperative Headache in Patients with Sellar Masses (HEADs‐uP Study)
- Author
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Tessa N. A. Slagboom, Tessel M. Boertien, Peter H. Bisschop, Eric Fliers, Johannes C. Baaijen, Jantien Hoogmoed, and Madeleine L. Drent
- Subjects
headache ,pituitary tumour ,sellar mass ,transsphenoidal surgery ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
ABSTRACT Introduction Sellar masses are common intracranial neoplasms. Their clinical manifestations vary widely and include headache. We aimed to determine whether the prevalence and characteristics of headache in patients with sellar tumours differ from the general population and to investigate the effect of tumour resection on this complaint. Methods We performed a prospective, controlled study in a single tertiary centre and included 57 patients that underwent transsphenoidal resection for a sellar mass (53% females, mean age 53.5 ± 16.4) and 29 of their partners (controls; 45% females, mean age 54.8 ± 14.9). Outcome measures were prevalence, characteristics and impact of headache 1 month preoperatively and at neurosurgical follow‐up 3 months postoperatively. Results Preoperatively, the prevalence of regular headache (≥1 time per month) was higher in patients than in controls (54% vs. 17%, p
- Published
- 2024
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