1. Respiratory Viruses
- Author
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Boncristiani, H.F., Criado, M.F., and Arruda, E.
- Subjects
respiratory viral infections ,viruses ,parainfluenza virus ,respiratory syncytial virus ,IRES, internal ribosomal entry site ,HRV, human rhinovirus ,ICAM, intercellular adhesion molecule ,ACE2, angiotensin-converting enzyme 2 ,Article ,LRI, lower respiratory infection ,SARS-CoV, SARS coronavirus ,Bocavirus ,LRTI, lower respiratory tract infection ,HBoV, human bocavirus ,HBD-2, human β-defensin 2 ,SARS, severe acute respiratory syndrome ,HMPV, human metapneumovirus ,ARDS, acute respiratory distress syndrome ,SARS ,LRT, lower respiratory tract ,HPIV, human parainfluenza virus ,ARI, acute respiratory infection ,common cold ,respiratory tract diseases ,Coronavirus ,CAR, Coxsackie B and adenovirus receptor ,HRSV, human respiratory syncytial virus ,UTR, untranslated region ,rhinovirus ,HE, hemagglutinin ,HCoV, human coronavirus ,LDLR, low-density lipoprotein receptor ,VLP, virus-like particle ,URI, upper respiratory infection ,Metapneumovirus ,respiratory adenovirus ,ECMO, extracorporeal membrane oxygenation - Abstract
Respiratory viruses are the most frequent causative agents of disease in humans, with significant impact on morbidity and mortality worldwide. Common respiratory agents from several virus families are well adapted to efficient person-to-person transmission and circulate in a global scale, and community-based studies conducted over the past five decades or so confirm that these viruses are the predominant etiological agents of acute respiratory infections (ARIs). The respiratory viruses that most commonly circulate in all continents as endemic or epidemic agents are influenza virus, respiratory syncytial virus, parainfluenza viruses, metapneumovirus, rhinovirus, coronaviruses, adenoviruses, and bocaviruses. Although vaccines and effective antiviral drugs are not yet available for most of these viruses, much progress has been made in the understanding of their biology and fundamental issues of host–parasite relationship. This article is a summary of the current knowledge about these viruses.
- Published
- 2009