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Your search keyword '"Pinkus Tober-Lau"' showing total 4 results
Start Over Author "Pinkus Tober-Lau" Journal emerging infectious diseases
4 results on '"Pinkus Tober-Lau"'

1. Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections

Author

Pinkus Tober-Lau, Henning Gruell, Kanika Vanshylla, Willi M. Koch, David Hillus, Philipp Schommers, Isabelle Suárez, Norbert Suttorp, Leif Erik Sander, Florian Klein, and Florian Kurth

Subjects
COVID-19, 2019 novel coronavirus disease, coronavirus disease, severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, viruses, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

To determine neutralizing activity against the severe acute respiratory syndrome coronavirus 2 ancestral strain and 4 variants of concern, we tested serum from 30 persons with breakthrough infection after 2-dose vaccination. Cross-variant neutralizing activity was comparable to that after 3-dose vaccination. Shorter intervals between vaccination and breakthrough infection correlated with lower neutralizing titers.

Published
2022
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2. Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

Author

Tatjana Schwarz, Pinkus Tober-Lau, David Hillus, Elisa T. Helbig, Lena J. Lippert, Charlotte Thibeault, Willi Koch, Irmgard Landgraf, Janine Michel, Leon Bergfeld, Daniela Niemeyer, Barbara Mühlemann, Claudia Conrad, Chantip Dang-Heine, Stefanie Kasper, Friederike Münn, Kai Kappert, Andreas Nitsche, Rudolf Tauber, Sein Schmidt, Piotr Kopankiewicz, Harald Bias, Joachim Seybold, Christof von Kalle, Terry C. Jones, Norbert Suttorp, Christian Drosten, Leif Erik Sander, Victor M. Corman, and Florian Kurth

Subjects
vaccine, mRNA, immunity, T cell, B cell, antibody, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical interventions for coronavirus disease remain crucial and that additional immunizations for the elderly might become necessary.

Published
2021
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3. Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021

Author

Pinkus Tober-Lau, Tatjana Schwarz, David Hillus, Jana Spieckermann, Elisa T. Helbig, Lena J. Lippert, Charlotte Thibeault, Willi Koch, Leon Bergfeld, Daniela Niemeyer, Barbara Mühlemann, Claudia Conrad, Stefanie Kasper, Friederike Münn, Frank Kunitz, Terry C. Jones, Norbert Suttorp, Christian Drosten, Leif Erik Sander, Florian Kurth, and Victor M. Corman

Subjects
vaccine, mRNA, outbreak, phylogeny, immunity, T cell, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

One week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 vaccinated and 4/4 unvaccinated residents. Despite considerable viral loads, vaccinated residents experienced mild symptoms and faster time to negative test results.

Published
2021
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4. Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021

Author

Florian Kurth, Pinkus Tober-Lau, Leon Bergfeld, David Hillus, Daniela Niemeyer, Barbara Mühlemann, Tatjana Schwarz, Stefanie Kasper, Lena J Lippert, Friederike Münn, Claudia Conrad, Elisa T Helbig, Victor M. Corman, Christian Drosten, Norbert Suttorp, Leif E. Sander, Terry Jones, Charlotte Thibeault, Frank Kunitz, Willi Koch, and Jana Spieckermann

Subjects
Microbiology (medical), Pediatrics, medicine.medical_specialty, Lineage (genetic), Epidemiology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021, mRNA, Infectious and parasitic diseases, RC109-216, phylogeny, Disease Outbreaks, respiratory infections, vaccine, antibody, Germany, Medicine, Humans, viruses, B cell, outbreak, business.industry, SARS-CoV-2, Vaccination, Dispatch, Outbreak, T cell, COVID-19, immunity, Long-Term Care, Care facility, zoonoses, Berlin, Long-term care, Infectious Diseases, Mild symptoms, coronavirus disease, business, Viral load, severe acute respiratory syndrome coronavirus 2
Abstract

One week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 vaccinated and 4/4 unvaccinated residents. Despite considerable viral loads, vaccinated residents experienced mild symptoms and faster time to negative test results.

Published
2021

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