1. Accumulation of L-type Bovine Prions in Peripheral Nerve Tissues
- Author
-
Yoshifumi Iwamaru, Morikazu Imamura, Yuichi Matsuura, Kentaro Masujin, Yoshihisa Shimizu, Yujing Shu, Megumi Kurachi, Kazuo Kasai, Yuichi Murayama, Shigeo Fukuda, Sadao Onoe, Ken’ichi Hagiwara, Yoshio Yamakawa, Tetsutaro Sata, Shirou Mohri, Hiroyuki Okada, and Takashi Yokoyama
- Subjects
atypical bovine spongiform encephalopathy ,Creutzfeldt-Jacob disease ,cattle ,distribution ,L-type ,nerve tissues ,Medicine ,Infectious and parasitic diseases ,RC109-216 - Abstract
We recently reported the intraspecies transmission of L-type atypical bovine spongiform encephalopathy (BSE). To clarify the peripheral pathogenesis of L-type BSE, we studied prion distribution in nerve and lymphoid tissues obtained from experimentally challenged cattle. As with classical BSE prions, L-type BSE prions accumulated in central and peripheral nerve tissues.
- Published
- 2010
- Full Text
- View/download PDF