1. Severe Acquired Toxoplasmosis Caused by Wild Cycle of Toxoplasma gondii, French Guiana
- Author
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Marie-Laure Dardé, Daniel Ajzenberg, Magalie Demar, Bernard Carme, Grelier, Elisabeth, Laboratoire Hospitalo-Universitaire de Parasitologie-Mycologie, Université des Antilles (UA)-Coordination Régionale de la lutte contre le Virus de L'Immunodéficience Humaine (COREVIH)-Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Unité de Maladies infectieuses et tropicales-Hygiène hospitalière (EA 3593), Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Université de Limoges (UNILIM), Neuroépidémiologie Tropicale et Comparée (NETEC), Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST FR CNRS 3503)-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Université de Limoges (UNILIM), Centre National de Référence (CNR) Toxoplasmose/Toxoplasma Biological Resource Center (BRC) (CNR Toxoplasmose-Toxoplasma BRC), and CHU Limoges
- Subjects
Felidae ,Acquired Toxoplasmosis ,lcsh:Medicine ,Communicable Diseases, Emerging ,Disease Outbreaks ,0302 clinical medicine ,Epidemiology ,Multilocus genotype ,MESH: Animals ,MESH: Communicable Diseases, Emerging ,MESH: Disease Outbreaks ,Mammals ,severe toxoplasmosis ,0303 health sciences ,biology ,MESH: Toxoplasma ,Dispatch ,French Guiana ,3. Good health ,atypical strains ,Infectious Diseases ,Acute Disease ,MESH: Toxoplasmosis ,MESH: Acute Disease ,epidemiology ,Host adaptation ,Toxoplasma ,Toxoplasmosis ,Adult ,Microbiology (medical) ,medicine.medical_specialty ,030231 tropical medicine ,Severe disease ,Toxoplasma gondii ,Animals, Wild ,macromolecular substances ,MESH: Mammals ,lcsh:Infectious and parasitic diseases ,03 medical and health sciences ,Amazonia ,MESH: French Guiana ,parasitic diseases ,medicine ,Animals ,Humans ,MESH: Animals, Wild ,lcsh:RC109-216 ,MESH: Humans ,030306 microbiology ,lcsh:R ,MESH: Adult ,wild cycle French Guiana ,biology.organism_classification ,medicine.disease ,Virology ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,Immunology ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,MESH: Felidae - Abstract
International audience; From 1998 through 2006, 44 cases of severe primary toxoplasmosis were observed in French Guiana in immunocompetent adults. Toxoplasma gondii isolates exhibited an atypical multilocus genotype. Severe disease in humans may result from poor host adaptation to neotropical zoonotic strains of T. gondii circulating in a forest-based cycle.
- Published
- 2009