1. Genetic Differences between Avian and Human Isolates of Candida dubliniensis
- Author
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Christophe d'Enfert, Brenda A. McManus, Derek J. Sullivan, Marie-Elisabeth Bougnoux, Gary P. Moran, Miles A. Nunn, David C. Coleman, Trinity College Dublin, Biologie et Pathogénicité fongiques, Institut Pasteur [Paris]-Institut National de la Recherche Agronomique (INRA), National Environmental Research Council Centre for Ecology and Hydrology, We thank Oscar Merne for assistance with collection of avian excrement samples and identification of specific species of birds at sampling sites. This study was supported by the Microbiology Research Unit, Dublin Dental School and Hospital.Ms McManus is a doctoral candidate in the Microbiology Research Unit at Dublin Dental School and Hospital, Trinity College Dublin. Her research interests focus on analysis of the population structure of the novel yeast pathogen C. dubliniensis by using MLST., Biologie et Pathogénicité fongiques (BPF), Institut National de la Recherche Agronomique (INRA)-Institut Pasteur [Paris] (IP), and Institut National de la Recherche Agronomique (INRA)-Institut Pasteur [Paris]
- Subjects
MESH: Sequence Analysis, DNA ,lcsh:Medicine ,MESH: Bird Diseases ,Charadriiformes ,Feces ,Zoonoses ,MESH: Animals ,genetics ,Mycological Typing Techniques ,[SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology ,Candida ,Genetics ,Candida dubliniensis ,0303 health sciences ,Fungal protein ,MESH: Ireland ,Candidiasis ,MESH: Feces ,dispatch ,MESH: Candidiasis ,Infectious Diseases ,MESH: Fungal Proteins ,multilocus sequencing typing ,epidemiology ,MESH: Zoonoses ,Disease transmission ,seabirds ,MLST ,Microbiology (medical) ,Biology ,Microbiology ,lcsh:Infectious and parasitic diseases ,Fungal Proteins ,03 medical and health sciences ,MESH: Candida ,MESH: Mycological Typing Techniques ,Animals ,Humans ,Point Mutation ,lcsh:RC109-216 ,030304 developmental biology ,MESH: Point Mutation ,MESH: Humans ,030306 microbiology ,Bird Diseases ,lcsh:R ,MESH: Charadriiformes ,Sequence Analysis, DNA ,biology.organism_classification ,Multilocus sequence typing ,fungi ,Ireland - Abstract
International audience; When Candida dubliniensis isolates obtained from seabird excrement and from humans in Ireland were compared by using multilocus sequence typing, 13 of 14 avian isolates were genetically distinct from human isolates. The remaining avian isolate was indistinguishable from a human isolate, suggesting that transmission may occur between humans and birds.
- Published
- 2009