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Your search keyword '"Leslie W, Woods"' showing total 3 results
Start Over Author "Leslie W, Woods" Journal emerging infectious diseases
3 results on '"Leslie W, Woods"'

1. Novel Polyomavirus associated with Brain Tumors in Free-Ranging Raccoons, Western United States

Author

Florante N. Dela Cruz, Federico Giannitti, Linlin Li, Leslie W. Woods, Luis Del Valle, Eric Delwart, and Patricia A. Pesavento

Subjects
Polyomavirus, raccoon, oncogenesis, malignant peripheral nerve sheath tumor, glioblastoma, oncogenic virus, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

Tumors of any type are exceedingly rare in raccoons. High-grade brain tumors, consistently located in the frontal lobes and olfactory tracts, were detected in 10 raccoons during March 2010–May 2012 in California and Oregon, suggesting an emerging, infectious origin. We have identified a candidate etiologic agent, dubbed raccoon polyomavirus, that was present in the tumor tissue of all affected animals but not in tissues from 20 unaffected animals. Southern blot hybridization and rolling circle amplification showed the episomal viral genome in the tumors. The multifunctional nuclear protein large T-antigen was detectable by immunohistochemical analyses in a subset of neoplastic cells. Raccoon polyomavirus may contribute to the development of malignant brain tumors of raccoons.

Published
2013
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2. West Nile Virus in California

Author

Leslie W. Woods, Minoo B. Madon, William K. Reisen, Robert E. Chiles, Stan Husted, Hugh D. Lothrop, John D. Edman, C K Cossen, and Vicki L. Kramer

Subjects
Microbiology (medical), St. Louis encephalitis virus, Epidemiology, Culex, West Nile virus, Climate, viruses, Clinical Sciences, lcsh:Medicine, Culex tarsalis, medicine.disease_cause, Microbiology, California, lcsh:Infectious and parasitic diseases, Birds, parasitic diseases, medicine, Seroprevalence, Culex pipiens quinquefasciatus, Animals, lcsh:RC109-216, Riparian zone, geography.geographical_feature_category, biology, Bird Diseases, Research, lcsh:R, virus diseases, biology.organism_classification, invasion, Virology, Archaeology, nervous system diseases, Infectious Diseases, Geography, Medical Microbiology, Public Health and Health Services, surveillance, Biological dispersal, Chickens, Sentinel Surveillance, West Nile Fever
Abstract

The spread of WNV in California is tracked., West Nile virus (WNV) was first isolated in California during July 2003 from a pool of Culex tarsalis collected near El Centro, Imperial County. WNV transmission then increased and spread in Imperial and Coachella Valleys, where it was tracked by isolation from pools of Cx. tarsalis, seroconversions in sentinel chickens, and seroprevalence in free-ranging birds. WNV then dispersed to the city of Riverside, Riverside County, and to the Whittier Dam area of Los Angeles County, where it was detected in dead birds and pools of Cx. pipiens quinquefasciatus. By October, WNV was detected in dead birds collected from riparian corridors in Los Angeles, west to Long Beach, and through inland valleys south from Riverside to San Diego County. WNV was reported concurrently from Arizona in mid-August and from Baja, Mexico, in mid-November. Possible mechanisms for virus introduction, amplification, and dispersal are discussed.

Published
2004

3. Novel Amdovirus in Gray Foxes

Author

Linlin Li, Leslie W. Woods, Eric Delwart, Chunlin Wang, Jennifer A. Luff, Deana L. Clifford, and Patricia A. Pesavento

Subjects
Microbiology (medical), Viral metagenomics, Epidemiology, viruses, animal diseases, Molecular Sequence Data, lcsh:Medicine, Foxes, Genome, Viral, Biology, Genome, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, gray fox, Phylogenetics, parasitic diseases, Aleutian Mink Disease Virus, Animals, lcsh:RC109-216, Phylogeny, 030304 developmental biology, Amdoparvovirus, Amdovirus, Genetics, 0303 health sciences, Phylogenetic tree, 030306 microbiology, Parvovirus, lcsh:R, parvovirus, Dispatch, Aleutian mink disease virus, virus diseases, biology.organism_classification, Virology, 3. Good health, Infectious Diseases, DNA, Viral, Urocyon
Abstract

We used viral metagenomics to identify a novel parvovirus in tissues of a gray fox (Urocyon cinereoargenteus). Nearly full genome characterization and phylogenetic analyses showed this parvovirus (provisionally named gray fox amdovirus) to be distantly related to Aleutian mink disease virus, representing the second viral species in the Amdovirus genus.

Published
2011
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