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Your search keyword '"Joëlle Petitjean"' showing total 2 results
Start Over Author "Joëlle Petitjean" Journal emerging infectious diseases
2 results on '"Joëlle Petitjean"'

1. Human Coronavirus NL63, France

Author

Astrid Vabret, Thomas Mourez, Julia Dina, Lia van der Hoek, Stéphanie Gouarin, Joëlle Petitjean, Jacques Brouard, and François Freymuth

Subjects
phylogenetic analysis, coronavirus NL63, molecular detection, pneumonia, bronchiolitis, multiplex assay, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

The human coronavirus NL63 (HCoV-NL63) was first identified in the Netherlands, and its circulation in France has not been investigated. We studied HCoV-NL63 infection in hospitalized children diagnosed with respiratory tract infections. From November 2002 to April 2003, we evaluated 300 respiratory specimens for HCoV-NL63. Of the 300 samples, 28 (9.3%) were positive for HCoV-NL63. The highest prevalence was found in February (18%). The main symptoms were fever (61%), rhinitis (39%), bronchiolitis (39%), digestive problems (33%), otitis (28%), pharyngitis (22%), and conjunctivitis (17%). A fragment of the spike protein gene was sequenced to determine the variety of circulating HCoV-NL63. Phylogenetic analysis indicated that strains with different genetic markers cocirculate in France.

Published
2005
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2. Human Coronavirus NL63, France

Author

Thomas Mourez, Stéphanie Gouarin, François Freymuth, Joëlle Petitjean, Jacques Brouard, Astrid Vabret, Lia van der Hoek, Julia Dina, Faculteit der Geneeskunde, AII - Amsterdam institute for Infection and Immunity, and Medical Microbiology and Infection Prevention

Subjects
Epidemiology, viruses, lcsh:Medicine, medicine.disease_cause, Keywords: phylogenetic analysis, Respiratory system, Child, Respiratory Tract Infections, Phylogeny, Coronavirus, coronavirus NL63, Respiratory tract infections, Reverse Transcriptase Polymerase Chain Reaction, virus diseases, respiratory system, humanities, Pharyngitis, multiplex assay, molecular detection, Infectious Diseases, Child, Preschool, RNA, Viral, bronchiolitis, France, medicine.symptom, Coronavirus Infections, Microbiology (medical), Human coronavirus NL63, medicine.medical_specialty, Adolescent, Biology, lcsh:Infectious and parasitic diseases, stomatognathic system, Internal medicine, medicine, Humans, pneumonia, lcsh:RC109-216, Amino Acid Sequence, Retrospective Studies, Base Sequence, Research, lcsh:R, Infant, Sequence Analysis, DNA, medicine.disease, biology.organism_classification, Virology, Otitis, Bronchiolitis, Genetic marker, Sequence Alignment
Abstract

Coronavirus NL63 was found in hospitalized children with upper and lower respiratory infections., The human coronavirus NL63 (HCoV-NL63) was first identified in the Netherlands, and its circulation in France has not been investigated. We studied HCoV-NL63 infection in hospitalized children diagnosed with respiratory tract infections. From November 2002 to April 2003, we evaluated 300 respiratory specimens for HCoV-NL63. Of the 300 samples, 28 (9.3%) were positive for HCoV-NL63. The highest prevalence was found in February (18%). The main symptoms were fever (61%), rhinitis (39%), bronchiolitis (39%), digestive problems (33%), otitis (28%), pharyngitis (22%), and conjunctivitis (17%). A fragment of the spike protein gene was sequenced to determine the variety of circulating HCoV-NL63. Phylogenetic analysis indicated that strains with different genetic markers cocirculate in France.

Published
2005
Full Text
View/download PDF

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