1. Epidemiologic History and Genetic Diversity Origins of Chikungunya and Dengue Viruses, Paraguay
- Author
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Julien Thézé, Shirley Villalba, Juan Torales, Sandra Irala, María Liz Gamarra, Marta Giovanetti, Jairo Andres Mendez Rico, Andrea Gómez, Cynthia Vazquez, Tulio de Oliveira, Ingra Morales Claro, Vasco Azevedo, Fernanda de Bruycker-Nogueira, Leticia Franco, Ana Maria Bispo de Filippis, Carlos F. Campelo de Albuquerque, Joilson Xavier, Vagner Fonseca, Marcos Cesar Lima de Mendonça, Luiz Carlos Junior Alcantara, Edward C. Holmes, Jaqueline Goes de Jesus, Tiago Gräf, Instituto Gonçalo Moniz, Partenaires INRAE, Department of Infectious Diseases, Istituto Superiore di Sanita [Rome], Universidade Federal de Minas Gerais, and University of Oxford [Oxford]
- Subjects
Serotype ,Epidemiology ,viruses ,vector-borne infections ,Infectious and parasitic diseases ,RC109-216 ,MESH: Chikungunya Fever ,MESH: Dengue ,Dengue virus ,medicine.disease_cause ,MESH: Dengue Virus ,Dengue fever ,Dengue ,0302 clinical medicine ,MESH: Arboviruses ,030212 general & internal medicine ,Chikungunya ,MESH: Genetic Variation ,MESH: Phylogeny ,MESH: Paraguay ,Phylogeny ,Phylogenetic tree ,Zika Virus Infection ,virus diseases ,3. Good health ,Infectious Diseases ,arboviruses ,Medicine ,Brazil ,Microbiology (medical) ,030231 tropical medicine ,MESH: Zika Virus ,Biology ,Arbovirus ,Virus ,03 medical and health sciences ,MESH: Zika Virus Infection ,parasitic diseases ,medicine ,Humans ,Genetic diversity ,chikungunya virus ,MESH: Humans ,dengue virus ,Research ,Genetic Variation ,Zika Virus ,biochemical phenomena, metabolism, and nutrition ,medicine.disease ,Virology ,Epidemiologic History and Genetic Diversity Origins of Chikungunya and Dengue Viruses, Paraguay ,genomic surveillance ,13. Climate action ,Paraguay ,nanopore sequencing ,Chikungunya Fever ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,MESH: Brazil - Abstract
International audience; C hikungunya virus (CHIKV), dengue virus (DENV), and Zika virus (ZIKV) are 3 of the most common arthropod-borne viruses (arboviruses) that infect humans. All are transmitted by the anthropophilic and urban-adapted Aedes aegypti and Ae. albopictus mosquito vectors (1). Driven by human movement and climate trends, the distribution of these mosquitoes is expanding along with the arboviruses they transmit (2). In Latin America, CHIKV and ZIKV have emerged since the mid-2000s, joining DENV, which is already endemic there (3). In this region, only Uruguay and Chile did not report autochthonous transmissions of one of these arboviruses during 2014-2019, highlighting the current state of endemicity (4). Paraguay is a landlocked country in the center of South America; it borders Bolivia, Brazil, and Argentina. DENV is endemic to Paraguay, and all 4 serotypes (DENV-1-4) have been detected there; in some seasons, multiple serotypes co-circulate (5,6). Phylogenetic analysis has shown that DENV genetic diversity in Paraguay is closely related to that in neighboring countries, particularly Brazil (7,8). However, more genomic surveillance studies in Paraguay are needed to learn more about this epidemiologic pattern. Cases
- Published
- 2021