1. Intravenous chlorpromazine for acute paediatric migraine.
- Author
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Löllgen, Ruth MC, Babl, Franz E, Mackay, Mark T, Hill, Ashley, and Palmer, Greta M
- Subjects
DRUG efficacy ,LENGTH of stay in hospitals ,HOSPITAL emergency services ,CONFIDENCE intervals ,MIGRAINE ,ANALGESICS ,CHLORPROMAZINE ,RETROSPECTIVE studies ,ACQUISITION of data ,COMPARATIVE studies ,OXYCODONE ,MEDICAL records ,DESCRIPTIVE statistics ,INTRAVENOUS injections ,DATA analysis software ,EVALUATION ,CHILDREN ,ADOLESCENCE - Abstract
Objective: In paediatric migraine, ibuprofen, acetaminophen and triptans are safe, effective therapies but there is scant paediatric data informing second‐line emergency treatment. Methods: Retrospective cohort study of children diagnosed with migraine at a tertiary children's hospital ED. Results: There were 207 children with migraine over a 1 year period. 46% received simple oral analgesia. 25% intravenous chlorpromazine, of whom 45% received further analgesia. Conclusions: While intravenous chlorpromazine as second‐line agent was mostly safe, it had unclear efficacy given the requirement for further treatment and hospital admissions. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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