1. Effect of cupric chloride on oxidative metabolism in the freshwater teleost, Tilapia mossambica
- Author
-
K Geethanjali, M. Balavenkatasubbaiah, K R Purushotham, R Ramamurthi, and A U Rani
- Subjects
food.ingredient ,Health, Toxicology and Mutagenesis ,Fresh Water ,Median lethal dose ,Lethal Dose 50 ,chemistry.chemical_compound ,Oxygen Consumption ,food ,Lactate dehydrogenase ,medicine ,Animals ,L-Lactate Dehydrogenase ,biology ,Muscles ,Succinate dehydrogenase ,Copper toxicity ,Fishes ,Public Health, Environmental and Occupational Health ,Tilapia ,General Medicine ,Metabolism ,medicine.disease ,Pollution ,Succinate Dehydrogenase ,Liver ,chemistry ,Biochemistry ,Toxicity ,biology.protein ,Oxidation-Reduction ,Anaerobic exercise ,Copper - Abstract
The freshwater teleost Tilapia mossambica was subjected to lethal (6.0 mg X liter-1 = LC50/48 hr) and sublethal (1.5 mg X liter-1 copper treatment for 1, 7, and 14 days. The whole animal oxygen consumption and the activity levels of succinate dehydrogenase and lactate dehydrogenase in liver and muscle were studied. The decrease in oxygen consumption and succinate dehydrogenase activity and significant increase in lactate dehydrogenase activity suggest that the stressed fish is meeting its energy requirements through anaerobic oxidation and these enzymes can be used as indicators in monitoring metal-induced toxicity in fish.
- Published
- 1984