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Erythema multiforme (EM) is an acute, self-limited, and sometimes recurrent skin disease considered to be a hypersensitivity reaction associated with certain medications and infections. EM has recently been recognized as a distinct disease differentiated from the Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). The aim of this study was to evaluate the clinical and histopathological characteristics of patients with EM. The retrospective study included 66 patients who received outpatient or inpatient treatment at the Dermatology department due to a diagnosis of EM between 2005 and 2017. Age, gender, etiological factor, recurrence, significant histopathological findings, presence of target lesions, mucosal involvement, and treatment metho ds were recorded. The 66 patients included 22 (33.3%) men and 44 (66.7%) women with a mean age of 36.7 ±13.9 years. The etiological factor was Herpes labialis in 36.4%, medication in 31.8%, Orf infection in 13.6%, and no etiological factor was detected in 18.2% of the patients. Although EM is a common entity in dermatology practice, there are a limited number of studies reporting on EM. The results indicated that EM can occur secondary to Orf infection. [ABSTRACT FROM AUTHOR]

Among skin cancers if not diagnosed early the highest death rate is for malign melanoma. Many studies has showed that multipl nevi lead to an increased risk of melanoma. It is a good option to take photos of patients in periodic intervals. In our study, we calculated the risk of melanoma in patients with acquired melanocytic nevi with 3-point checklist and digital dermoscopy and we aimed to compare the results and their advantages to each other. We enrolled 300 patients with acquired melanocytic nevi in our study. Cases we enrolled in our study were recorded in the pre-prepared patient follow-up form. In this study Fotofinder HD (Germany) digital dermoscopy instruments were used. Lesions that were regarded as malign by 3-point scoring method were excised and histopathologically evaluated. In statistical calculations significance level of 5% was used and calculations were made with SPSS (ver: 13) statistical package program. 157 of our patients were male (52.3%) and 143 (47.7%) were female. Sensitivity of digital dermoscopy was determined as 86% according to the 3-point checklist. 6 Of the 300 patients were diagnosed as malign melanoma. Sensitivity of the 3-point checklist was determined as 97%. In our study, the results of 3-point checklist were detected higher than previous studies. Since digital dermoscopy is easy to use, this method is convenient especially for inexperienced physicians in the diagnosis of malignancy. But dermoscopic algorithms remain as the first choice for specialist physicians. [ABSTRACT FROM AUTHOR]