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Your search keyword '"Neurobehaviour"' showing total 3 results
Start Over Descriptor "Neurobehaviour" Journal early human development
3 results on '"Neurobehaviour"'

1. Relationship between very early brain structure and neuromotor, neurological and neurobehavioral function in infants born <31 weeks gestational age.

Author

George, Joanne M., Fiori, Simona, Fripp, Jurgen, Pannek, Kerstin, Guzzetta, Andrea, David, Michael, Ware, Robert S., Rose, Stephen E., Colditz, Paul B., and Boyd, Roslyn N.

Subjects
*NEUROMUSCULAR diseases, *GESTATIONAL age, *MAGNETIC resonance imaging, *REFLEXES, *PREMATURE infants
Abstract

Aim: This study aimed to examine associations between structural MRI and concurrent motor, neurological and neurobehavioral measures at 30-32 weeks postmenstrual age (PMA; 'Early'), and at term equivalent age ('Term').Method: In this prospective cohort study, infants underwent Early MRI (n = 119; 73 male; median 32 weeks 1 day PMA) and Term MRI (n = 102; 61 male; median 40 weeks 4 days PMA) at 3 T. Structural images were scored generating white matter (WM), cortical gray matter, deep gray matter, cerebellar and global brain abnormality scores. Clinical measures were General Movements Assessment (GMs), Hammersmith Neonatal Neurological Examination (HNNE) and NICU Neonatal Neurobehavioral Scale (NNNS). The Premie-Neuro was administered Early and the Test of Infant Motor Performance (TIMP) and a visual assessment at Term.Results: Early MRI cerebellar scores were strongly associated with neurological components of HNNE (reflexes), NNNS (Hypertonicity), the Premie-Neuro neurological subscale (regression coefficient β = -0.06; 95% confidence interval CI = -0.09, -0.04; p < .001) and cramped-synchronized GMs (β = 1.10; 95%CI = 0.57, 1.63; p < .001). Term MRI WM and global scores were strongly associated with the TIMP (WM β = -1.02; 95%CI = -1.67, -0.36; p = .002; global β = -1.59; 95%CI = -2.62, -0.56; p = .001).Interpretation: Brain structure on Early and Term MRI was associated with concurrent motor, neurological and neurobehavioral function in very preterm infants. [ABSTRACT FROM AUTHOR]

Published
2018
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2. Relationship between very early brain structure and neuromotor, neurological and neurobehavioral function in infants born <31 weeks gestational age

Author

Robert S. Ware, Joanne M. George, Jurgen Fripp, Stephen E. Rose, Andrea Guzzetta, Simona Fiori, Roslyn N. Boyd, Paul B. Colditz, Michael David, and Kerstin Pannek

Subjects
Male, General movements assessment, Pediatrics, medicine.medical_specialty, Neurological examination, Neuromotor, White matter, 03 medical and health sciences, Magnetic resonance imaging, Neurobehaviour, Neurological, Preterm, Pediatrics, Perinatology and Child Health, Obstetrics and Gynecology, Child Development, 0302 clinical medicine, 030225 pediatrics, medicine, Humans, Prospective cohort study, medicine.diagnostic_test, business.industry, Infant, Newborn, Postmenstrual Age, Brain, Gestational age, Perinatology and Child Health, Magnetic Resonance Imaging, medicine.anatomical_structure, Motor Skills, Infant Behavior, Female, Abnormality, business, Infant, Premature, 030217 neurology & neurosurgery
Abstract

This study aimed to examine associations between structural MRI and concurrent motor, neurological and neurobehavioral measures at 30-32 weeks postmenstrual age (PMA; 'Early'), and at term equivalent age ('Term').In this prospective cohort study, infants underwent Early MRI (n = 119; 73 male; median 32 weeks 1 day PMA) and Term MRI (n = 102; 61 male; median 40 weeks 4 days PMA) at 3 T. Structural images were scored generating white matter (WM), cortical gray matter, deep gray matter, cerebellar and global brain abnormality scores. Clinical measures were General Movements Assessment (GMs), Hammersmith Neonatal Neurological Examination (HNNE) and NICU Neonatal Neurobehavioral Scale (NNNS). The Premie-Neuro was administered Early and the Test of Infant Motor Performance (TIMP) and a visual assessment at Term.Early MRI cerebellar scores were strongly associated with neurological components of HNNE (reflexes), NNNS (Hypertonicity), the Premie-Neuro neurological subscale (regression coefficient β = -0.06; 95% confidence interval CI = -0.09, -0.04; p .001) and cramped-synchronized GMs (β = 1.10; 95%CI = 0.57, 1.63; p .001). Term MRI WM and global scores were strongly associated with the TIMP (WM β = -1.02; 95%CI = -1.67, -0.36; p = .002; global β = -1.59; 95%CI = -2.62, -0.56; p = .001).Brain structure on Early and Term MRI was associated with concurrent motor, neurological and neurobehavioral function in very preterm infants.

Published
2018

3. Relationships between early postnatal cranial ultrasonography linear measures and neurobehaviour at term-equivalent age in infants born <30 weeks' gestational age.

Author

Cuzzilla, Rocco, Olsen, Joy E., Eeles, Abbey L., Rogerson, Sheryle R., Anderson, Peter J., Cowan, Frances M., Doyle, Lex W., Cheong, Jeanie L.Y., and Spittle, Alicia J.

Subjects
*GESTATIONAL age, *SIZE of brain, *ULTRASONIC imaging, *NEURAL development, *CORPUS callosum, *FETAL echocardiography, *INFANTS
Abstract

Background: The relationship between early postnatal brain development and neurobehaviour at term-equivalent age (TEA) remains uncertain.Aim: We aimed to explore relationships between early postnatal cranial ultrasonography (cUS) linear measures of brain size and brain growth with neurobehaviour at TEA in infants born <30 weeks' gestational age (GA).Study Design: Prospective observational cohort study.Subjects: 137 infants born <30 weeks' GA without major brain injury on neonatal cUS.Outcome Measures: Neurobehaviour at TEA assessed using the General Movements Assessment (GMA) and Hammersmith Neonatal Neurological Examination (HNNE).Results: The GMA was administered in 115/137 (84%) infants; 80 (70%) presented with abnormal general movements (GMs) (79 poor repertoire, 1 cramped synchronised). The HNNE was assessed in 106/137 (77%) infants; 52 (49%) had a suboptimal total score. With respect to brain size, larger measures of the corpus callosum length (CCL) and right anterior horn width (AHW) at 1-month were related to lower risk of abnormal GMs, and larger measures of the biparietal diameter at 1-week and 2-months were related to lower risk of a suboptimal HNNE. As for brain growth, increases of the CCL and transcerebellar diameter between birth and 1-month, and left and right AHWs between 1- and 2-months, were related to lower risk of abnormal GMs.Conclusion: Early postnatal brain size and brain growth were related to neurobehaviour at TEA in infants born <30 weeks' GA. This study provides preliminary evidence for the prognostic utility of early postnatal cUS linear measures as potential markers of neurodevelopment in later childhood. [ABSTRACT FROM AUTHOR]

Published
2022
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