1. Photodegradation Study of Sodium Usnate Solution: Influence of pH
- Author
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C. Coiffard, Y. De Roeck-Holtzhauer, and Laurence Coiffard
- Subjects
Pharmacology ,Aqueous solution ,Light ,Chemistry ,Drug Storage ,Organic Chemistry ,Inorganic chemistry ,Kinetics ,Pharmaceutical Science ,Ph dependent ,Hydrogen-Ion Concentration ,Solutions ,Drug Stability ,Drug Discovery ,Photochemical degradation ,Dermatologic Agents ,Sodium usnate ,Photodegradation ,Heterocyclic Compounds, 3-Ring ,Degradation rate constant ,Antibacterial agent - Abstract
Photodegradation of 2.6 x 10(-5) M aqueous solutions of sodium usnate at various pH was studied. Photodegradation appeared to follow first-order kinetics and was found to be pH dependent. The degradation rate constant was calculated to be 9.20 x 10(-4) min-1, 5.93 x 10(-4) min-1, 9.69 x 10(-4) min-1, and 9.88 x 10(-4) min-1 at pH 6, pH 7, pH 8, and pH 9, respectively.
- Published
- 1999
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