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Your search keyword '"Maisey, Nick"' showing total 6 results
Start Over Author "Maisey, Nick" Journal diseases of the esophagus
6 results on '"Maisey, Nick"'

1. 568. THE PROGNOSTIC EFFECT OF PATHOLOGICAL LYMPH NODE REGRESSION AFTER NEOADJUVANT CHEMOTHERAPY FOR OESOPHAGEAL ADENOCARCINOMA – A MULTICENTRE STUDY

Author

Moore, Jonathan, primary, Green, Michael, additional, Van Hemelrijck, Mieke, additional, Deere, Harriet, additional, Evans, Richard PT, additional, Elshafie, Mona, additional, Lavery, Anita, additional, McGuigan, Andrew, additional, Douglas, Rosalie, additional, Mcmanus, Damian, additional, Horne, Joanne, additional, Walker, Robert, additional, Mir, Hira, additional, Terlizzo, Monica, additional, Kamarajah, Sivesh K, additional, Santaolalla, Aida, additional, Maisey, Nick, additional, Lumsden, Ailsa, additional, Ngan, Sarah, additional, Kelly, Mark, additional, Baker, Cara R, additional, Kumar, Sacheen, additional, Lagergren, Jesper, additional, Allum, William H, additional, Gossage, James A, additional, Griffiths, Ewan, additional, Grabsch, Heike I, additional, Turkington, Richard C, additional, Underwood, Tim, additional, Smyth, Elizabeth, additional, Fitzgerald, Rebecca, additional, Cunningham, David, additional, and Davies, Andrew R, additional

Published
2022
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2. 354. THE PARADIGM OF INACCURACIES IN STAGING EARLY OESOPHAGEAL ADENOCARCINOMA

Author

Reyhani, Arasteh, primary, Gimson, Eliza, additional, Baker, Cara, additional, Kelly, Mark, additional, Maisey, Nick, additional, Meenan, John, additional, Subesinghe, Manil, additional, Hill, Mark, additional, Lagergren, Jesper, additional, Gossage, James, additional, Zeki, Sebastian, additional, Dunn, Jason, additional, and Davies, Andrew, additional

Published
2022
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3. 577. FDG PT-CT METABOLIC TUMOUR AND NODAL RESPONSE AS A PREDICTOR OF PATHOLOGICAL RESPONSE AND SURVIVAL IN PATIENTS WITH OESOPHAGEAL ADENOCARCINOMA

Author

Moore, Jonathan, primary, Subesinghe, Manil, additional, Santaolalla, Aida, additional, Green, Michael, additional, Deere, Harriet, additional, Van Hemelrijck, Mieke, additional, Lagergren, Jesper, additional, Chicklore, Sugama, additional, Maisey, Nick, additional, Kelly, Mark, additional, Gossage, James A, additional, Baker, Cara R, additional, and Davies, Andrew R, additional

Published
2022
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4. 646 PREDICTING RESPONSE TO NEOADJUVANT CHEMOTHERAPY IN PATIENTS WITH OESOPHAGEAL ADENOCARCINOMA

Author

Bott, Rebecca, primary, George, Gincy, additional, McEwen, Ricardo, additional, Zylstra, Janine, additional, Knight, William, additional, Baker, Cara, additional, Kelly, Mark, additional, Griffin, Nyree, additional, Mcaddy, Naami, additional, Maisey, Nick, additional, Van Hemelrijck, Mieke, additional, Gossage, James, additional, Lagergren, Jesper, additional, and Davies, Andrew, additional

Published
2021
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5. P107 PREDICTION OF A POSITIVE CIRCUMFERENTIAL RESECTION MARGIN IN ADENOCARCINOMA OF THE ESOPHAGUS

Author

Goh Vicky, Jacques Audrey, Yip Connie, Griffin Nyree, Landau David, Kelly Mark, Van Hemelrijck Mieke, R C Knight William, R Davies Andrew, Zylstra Janine, R Baker Cara, Wulaningsih Wahyu, Largergren Jesper, Gaya DrAndrew, Maisey Nick, and A Gossage James

Subjects
medicine.medical_specialty, medicine.anatomical_structure, business.industry, Gastroenterology, medicine, Adenocarcinoma, Circumferential resection margin, General Medicine, Radiology, Esophagus, medicine.disease, business
Abstract

Aim To determine if a positive circumferential resection margin (CRM) can be predicted in patients with esophageal adenocarcinoma undergoing neo-adjuvant chemotherapy prior to surgery Methods 223 patients were included in this study. Multivariable analyses of clinico-pathological and computed tomography (CT) imaging predictors were performed to evaluate the likelihood of a positive CRM at initial staging and following neoadjuvant chemotherapy, with prediction models constructed. Area under curve (AUC) with 95% confidence interval (CI) from 1000 bootstrapping was assessed. Results Advanced clinical T-stage (T3-4) (odds ratio, OR 2.93 95%CI 1.03-9.48) and poor tumor differentiation (OR 2.84, 95%CI 1.39-6.01) were independently associated with an increased risk of a positive CRM. Non response to chemotherapy as estimated by CT independently corresponded with an increased risk of CRM positivity (OR 3.38 95% CI 1.43-8.50). Additional CT evidence of local invasion/pleural thickening and higher CT tumor volume (14cm3) improved the performance of a prediction model, including all above parameters; with AUC (c-index) of 0.76 (0.68-0.83). Conclusion Combining advanced clinical T-stage, poor tumor differentiation, CT non-response to chemotherapy, higher CT tumor volume and local invasion may be helpful in selecting patients for intensification of neo-adjuvant treatment prior to resection.

Published
2019

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