1. Efficacy of selected oral chemotherapeutants against Ichthyophthirius multifiliis (Ciliophora: Ophyroglenidae) infecting rainbow trout Oncorhynchus mykiss.
- Author
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Shinn AP, Wootten R, Côté I, and Sommerville C
- Subjects
- Administration, Oral, Amprolium therapeutic use, Animal Feed, Animals, Antiprotozoal Agents administration & dosage, Ciliophora growth & development, Ciliophora Infections drug therapy, Clopidol administration & dosage, Clopidol therapeutic use, Decoquinate administration & dosage, Decoquinate therapeutic use, Dose-Response Relationship, Drug, Fish Diseases parasitology, Monensin administration & dosage, Monensin therapeutic use, Nicarbazin administration & dosage, Nicarbazin therapeutic use, Pyrans administration & dosage, Pyrans therapeutic use, Random Allocation, Treatment Outcome, Antiprotozoal Agents therapeutic use, Ciliophora drug effects, Ciliophora Infections veterinary, Fish Diseases drug therapy, Oncorhynchus mykiss parasitology
- Abstract
The chemotherapeutic efficacy of 6 in-feed compounds against Ichthyophthirius multifiliis Fouquet, 1876 was assessed using experimental infections of rainbow trout Oncorhynchus mykiss (Walbaum) fingerlings. Trial doses of 104 ppm amprolium hydrochloride or 65 ppm clopidol fed to fish for 10 d prior to infection significantly reduced the number of trophonts establishing in trout fingerlings by 62.0 and 35.2% respectively. In-feed treatments of infected trout with either 63 or 75 ppm amprolium hydrochloride, 92 ppm clopidol, or 38, 43 or 47 ppm salinomycin sodium for 10 d also significantly reduced the number of surviving trophonts by 77.6 and 32.2% for amprolium, 20.1% for clopidol and 80.2, 71.9 and 93.3% respectively for salinomycin sodium.
- Published
- 2003
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