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4 results on '"Satoru, Iida"'

1. Clinical Significance of Lymph Node Ratio and Location of Nodal Involvement in Patients with Right Colon Cancer

Author

Satoru Iida, Tetsuro Higuchi, Megumi Ishiguro, Masayuki Enomoto, Hirotoshi Kobayashi, Shunsuke Kato, Toshiaki Ishikawa, Hiroyuki Uetake, and Kenichi Sugihara

Subjects
Male, Oncology, medicine.medical_specialty, Colon, Colorectal cancer, Risk Factors, Colon surgery, Internal medicine, medicine, Humans, Clinical significance, Stage (cooking), Ligation, Survival rate, Lymph node, Neoplasm Staging, Retrospective Studies, business.industry, Gastroenterology, Retrospective cohort study, medicine.disease, Survival Rate, Dissection, medicine.anatomical_structure, Lymphatic Metastasis, Colonic Neoplasms, Lymph Node Excision, Female, Surgery, Lymph Nodes, Radiology, Neoplasm Recurrence, Local, business
Abstract

Background/Aims: Increasing negative lymph node count has been reported to be associated with better outcomes in patients with colon cancer. The present study aimed to clarify the clinical significance of the lymph node ratio (LNR) and location of lymph node metastasis (LNM) in patients with stage III right colon cancer. Methods: We enrolled 820 patients who had undergone curative resection due to colon cancer at a single institution between 1991 and 2005. Among them, 197 underwent curative resection for T2–T4 right colon cancer. We evaluated the oncological outcomes according to LNR (quartiles) and distribution of LNM (n1 = LNM adjacent to the colon or along the vascular arcades of the marginal arteries; n2 = LNM along the major vessels; n3 = LNM near the roots of the major vessels). Results: The rates of LNM in T2, T3 and T4 right colon cancer were 11.1, 38.6 and 58.0%, respectively (p < 0.0001). Recurrence rates were 27.3, 37.5 and 57.1% in patients with n1, n2 and n3 LNM, respectively (p < 0.0001). LNR (p < 0.0001) and distribution of LNM (p = 0.046) were independent risk factors for recurrence in patients with stage III right colon cancer. Conclusions: Some patients with extensive LNM benefited from lymph node dissection with high ligation. Those with T3–T4 right colon cancer are suitable candidates for lymph node dissection with high ligation. Adding the concept of LNR and location of LNM to conventional TNM staging could improve the accuracy of evaluating nodal status.

Published
2011

2. Validation and Clinical Use of the Japanese Classification of Colorectal Carcinomatosis: Benefit of Surgical Cytoreduction Even without Hyperthermic Intraperitoneal Chemotherapy

Author

Hiroyuki Uetake, Masayuki Enomoto, Tetsuro Higuchi, Satoru Iida, Hirotoshi Kobayashi, Toshiaki Ishikawa, Kenichi Sugihara, and Megumi Ishiguro

Subjects
Male, Oncology, medicine.medical_specialty, Peritoneal metastasis, business.industry, Colorectal cancer, Carcinoma, Liver Neoplasms, Gastroenterology, Middle Aged, Prognosis, medicine.disease, Peritoneal carcinomatosis, Sex Factors, Japan, Internal medicine, Humans, Medicine, Female, Surgery, Hyperthermic intraperitoneal chemotherapy, Colorectal Neoplasms, business, Peritoneal Neoplasms, Proportional Hazards Models
Abstract

Background: This study aimed to validate an easy to use practical classification of peritoneal metastasis arising from colorectal cancer. Patients and Methods: Data from 2,134 consecutive patients who underwent resection for colorectal cancer at a single institution were reviewed. Peritoneal metastasis was classified depending on extent into three groups (P1–P3). The macroscopic radical resection rates and survival of patients with colorectal cancer complicated with peritoneal metastasis were analyzed. Results: Of the 2,134 patients, 116 (5.4%) had peritoneal metastasis. Among them, 20 (17.2%) underwent macroscopic radical resection. Tumor location on the right side was associated with more extensive peritoneal metastasis (p = 0.010). Male gender (p = 0.0027), liver metastasis (p = 0.0021), and P3 peritoneal metastasis were independent risk factors for noncurative resection. The Cox proportional hazards model showed that gender (p = 0.031), operation period (p = 0.031), and macroscopic radical resection for colorectal cancer and peritoneal metastasis (p = 0.031) were independent prognostic factors. Conclusions: Being female with left colon cancer complicated with P1 or P2 peritoneal metastasis is a good indicator for macroscopic radical resection if liver metastasis is absent. The present classification helped to determine surgical indication for patients with colorectal cancer complicated with synchronous peritoneal metastasis in routine clinical practice.

Published
2010

3. Contents Vol. 27, 2010

Author

Mikiko Ueda, Hirotoshi Kobayashi, Yasutsugu Takada, Jong Yeul Lee, Masayuki Enomoto, Koichiro Hata, J. Karvonen, Fumihiko Miura, Zhongxia Dou, Keita Wada, Susumu Kadowaki, Kenichiro Kato, Takashi Kosaka, Seok Ling Ong, Hirofumi Kawanaka, Young-Woo Kim, Jong Seok Lee, Chan Gyoo Kim, Morimasa Tomikawa, Ryo Takagawa, Seisuke Sakamoto, Daisuke Korenaga, Hodaka Amano, Takehide Asano, Edgar J. B. Furnée, Justin H. Nguyen, Yasuhiro Ogura, Linhua Yao, Xiayue Huang, Chikara Kunisaki, Shinji Tanaka, Shinji Uemoto, Tohru Saito, Naotaka Hashimoto, Kazuaki Tanabe, Yoshihiko Maehara, Ruihua Shi, Lei Wang, Jun Ho Lee, Kenji Takenaka, Hongman Yoon, Matthew S. Metcalfe, Nao Kinjo, Hideki Yamamoto, Hirotoshi Akiyama, Yukihiko Tokunaga, Timothy D J Knowles, Takahisa Suzuki, Niels van Lelyveld, Tomohiko Akahoshi, Omer Al-Taan, Hideki Ohdan, Jun Kimura, Noriaki Tokumoto, Sook Ryun Park, Satoru Iida, Rebecca Levine, Myung Cherl Kook, Eric J. Hazebroek, Hideo Uehara, Byung-Ho Nam, Yuqin Li, Werner A. Draaisma, Stephen Priest, Itaru Endo, Gianpiero Gravante, Tadahiro Takada, Markus W. Büchler, J. Ovaska, Ju Wang, Naoyuki Toyota, Toshiaki Ishikawa, Etsuro Hatano, Hidetaka Ono, Il Ju Choi, Bang Wool Eom, Hiroyuki Uetake, Hirochika Makino, Hirokazu Sasaki, Ivo A. M. J. Broeders, Ashley R. Dennison, Feng Chen, André J.P.M. Smout, Megumi Ishiguro, Tetsuro Higuchi, Soo-Jeong Cho, Kenichi Sugihara, Sawako Maeno, Mureo Kasahara, Shiro Oka, Yuji Urabe, Kohei Ogawa, Toshimi Kaido, Keun Won Ryu, Tomohide Hori, Tianfu Wang, P. Salminen, Yukihide Yonekawa, Kozo Konishi, Hiroto Egawa, Koichi Hayano, Ann-Marie T. Baine, Fumitaka Oike, Makoto Shibuya, David M. Lloyd, Guoxin Zhang, and Dan Liu

Subjects
Traditional medicine, business.industry, Gastroenterology, Medicine, Surgery, business
Published
2010

4. Subject Index Vol. 27, 2010

Author

Hiroto Egawa, Naoyuki Toyota, Bang Wool Eom, Jun Ho Lee, Seok Ling Ong, Linhua Yao, Hirofumi Kawanaka, Hirotoshi Akiyama, Noriaki Tokumoto, Megumi Ishiguro, Sook Ryun Park, Koichi Hayano, Chan Gyoo Kim, Shinji Uemoto, Ann-Marie T. Baine, Tadahiro Takada, Satoru Iida, Young-Woo Kim, Hodaka Amano, Edgar J. B. Furnée, Masayuki Enomoto, Toshiaki Ishikawa, Kenichiro Kato, Takashi Kosaka, Ju Wang, Morimasa Tomikawa, Timothy D J Knowles, Seisuke Sakamoto, Soo-Jeong Cho, Markus W. Büchler, Kenichi Sugihara, Il Ju Choi, Xiayue Huang, Takehide Asano, Koichiro Hata, P. Salminen, Hideo Uehara, Fumitaka Oike, Byung-Ho Nam, Sawako Maeno, Takahisa Suzuki, Tomohiko Akahoshi, Werner A. Draaisma, Toshimi Kaido, Matthew S. Metcalfe, Keun Won Ryu, Ruihua Shi, Hiroyuki Uetake, Shiro Oka, Itaru Endo, Makoto Shibuya, Niels van Lelyveld, Rebecca Levine, Myung Cherl Kook, David M. Lloyd, Mikiko Ueda, André J.P.M. Smout, Hirotoshi Kobayashi, Yuqin Li, Tianfu Wang, Jong Yeul Lee, Tomohide Hori, Stephen Priest, Yukihide Yonekawa, J. Karvonen, Zhongxia Dou, Ivo A. M. J. Broeders, Kazuaki Tanabe, J. Ovaska, Naotaka Hashimoto, Guoxin Zhang, Feng Chen, Yoshihiko Maehara, Kenji Takenaka, Kozo Konishi, Lei Wang, Fumihiko Miura, Jun Kimura, Nao Kinjo, Hideki Yamamoto, Hongman Yoon, Dan Liu, Kohei Ogawa, Susumu Kadowaki, Etsuro Hatano, Ashley R. Dennison, Chikara Kunisaki, Shinji Tanaka, Mureo Kasahara, Hirokazu Sasaki, Keita Wada, Omer Al-Taan, Hideki Ohdan, Eric J. Hazebroek, Tetsuro Higuchi, Yasuhiro Ogura, Gianpiero Gravante, Yuji Urabe, Hirochika Makino, Hidetaka Ono, Yasutsugu Takada, Daisuke Korenaga, Jong Seok Lee, Ryo Takagawa, Justin H. Nguyen, Tohru Saito, and Yukihiko Tokunaga

Subjects
medicine.medical_specialty, Index (economics), business.industry, Internal medicine, Gastroenterology, medicine, Surgery, Medical physics, Subject (documents), business
Published
2010

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