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Start Over Author "Roncoroni L." Journal digestive and liver disease
32 results on '"Roncoroni L."'

2. OC.07.4: FEASIBILITY, ACCURACY AND REPRODUCIBILITY OF THE ULTRASOUND MEASUREMENT OF PSOAS MUSCLE COMPARED TO BIOELECTRICAL IMPEDANCE ANALYSIS FOR THE EVALUATION OF SKELETAL MUSCLE MASS IN PATIENTS WITH IBD

Author

Fichera, A., primary, Costantino, A., additional, Baldrighi, S., additional, Piagnani, A., additional, Tagliamonte, G., additional, Santagata, F., additional, Stalla, F., additional, Pessarelli, T., additional, Vecchi, M., additional, Elli, L., additional, Roncoroni, L., additional, Caprioli, F., additional, and Fraquelli, M., additional

Published
2024
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4. T.03.4 NOVEL STRATEGIES TO MONITOR CELIAC DISEASE

Author

Piagnani, A., primary, Roncoroni, L., additional, Lombardo, V., additional, Scricciolo, A., additional, Costantino, A., additional, Scaramella, L., additional, Nandi, N., additional, Vecchi, M., additional, Doneda, L., additional, Topa, M., additional, and Elli, L., additional

Published
2022
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32. Anti-SARS-CoV-2 immunoglobulin profile in patients with celiac disease living in a high incidence area

Author

V. Lombardo, David S Sanders, Luisa Doneda, Federica Facciotti, Donatella Barisani, Valentina Vaira, Bernardo Dell'Osso, Lucia Scaramella, A. Scricciolo, Maurizio Vecchi, Leda Roncoroni, Luca Elli, A. Costantino, Elli, L, Facciotti, F, Lombardo, V, Scricciolo, A, Sanders, D, Vaira, V, Barisani, D, Vecchi, M, Costantino, A, Scaramella, L, Dell'Osso, B, Doneda, L, and Roncoroni, L

Subjects
Adult, Male, medicine.medical_specialty, Tissue transglutaminase, Duodenum, Disease, Gastroenterology, Diet, Gluten-Free, Atrophy, Internal medicine, medicine, Humans, Celiac disease, Receptor, Duodenal atrophy, Hepatology, biology, Alimentary Tract, business.industry, SARS-CoV-2, Incidence (epidemiology), Incidence, COVID-19, Histology, medicine.disease, Small bowel, Immunoglobulin A, Italy, Immunoglobulin G, biology.protein, Patient Compliance, Female, Angiotensin-Converting Enzyme 2, Antibody, business, ACE2 receptor, Gluten
Abstract

Background and aim How symptoms and antibodies related to SARS-CoV-2 infection develop in patients with celiac disease (CD) is unclear. We aimed to investigate the impact of SARS-CoV-2 infection in CD patients. Methods CD patients were interviewed about the development of COVID-19 symptoms, compliance with anti-virus measures and adherence to a gluten-free diet (GFD). The presence of anti-SARS-CoV-2 IgG and IgA (anti-RBD and N proteins) was compared to that in non-CD subjects. Expression of the duodenal ACE2 receptor was investigated. When available, data on duodenal histology, anti-tissue transglutaminase IgA (tTGA), comorbidities and GFD adherence were analyzed. Results Of 362 CD patients, 42 (12%) reported COVID-19 symptoms and 21% of these symptomatic patients presented anti-SARS-CoV-2 Ig. Overall, 18% of CD patients showed anti-SARS-CoV-2 Ig versus 25% of controls (p = 0.18). CD patients had significantly lower levels of anti-N IgA. tTGA, duodenal atrophy, GFD adherence or other comorbidities did not influence symptoms and/or antibodies. The ACE2 receptor was detected in the non-atrophic duodenal mucosa of patients; atrophy was associated with lower expression of the ACE2 receptor. Conclusion CD patients have an anti-SARS-CoV-2 Ig profile similar to non-celiac controls, except for anti-N IgA. No risk factors were identified among CD parameters and GFD adherence.

Published
2021

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