22 results on '"LONGO M"'
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2. PNPLA3, MBOAT7 and TM6SF2 modify mitochondrial dynamics in NAFLD patients: Dissecting the role of cell-free circulating mtDNA and copy number
3. B-Klotho deficiency in hepatic stellate cells (HSCs) prompts inflammation, oxidative stress and a pro-fibrotic phenotype
4. Combined hepatic and adipose tissue transcriptomics highlights circulating NASH biomarkers
5. The overexpression of TM6SF2 and/or MBOAT7 wild-type genes restores the mitochondrial lifecycle and activity in an in vitro NAFLD model
6. The I148M PNPLA3 variant mitigates Niacin beneficial effects: how the genetic screening in NAFLD patients gains value
7. The co-presence of PNPLA3, MBOAT7 and TM6SF2 loss-of-functions impairs mitochondrial morphology and number in severe NAFLD patients
8. Modeling KLB deficiency by genome editing in hepatocytes: from oxidative stress and inflammation towards enhanced proliferation
9. New steps forward in learning about the use of DGAT1 and DGAT2 inhibitors for MASLD management: limits and benefits for their single or combined application
10. Unravelling the role of mitochondrial dysfunction in the switching towards progressive MASLD by exploiting an AMLN diet-fed mouse model
11. Circulating mitochondrial bioenergetic profile reflects the hepatic one and represents a non-invasive biomarker of disease severity in MASLD genetically predisposed individuals
12. The PSRC1 rs599839 A>G variant disentangles the risk of coronary artery disease and hepatocellular carcinoma in Italian NAFLD patients
13. TM6SF2/PNPLA3/MBOAT7 loss-of-function genetic variants impact on NAFLD development and progression both in patients and in in vitro models
14. The role of variant rs17618244 of KLB gene in MAFLD-related fibrosis
15. Metabolic reprogramming and mitochondrial dysfunction in HepG2 cells as potential drivers of AIP pathophysiology
16. The I148M PNPLA3 variant mitigates Niacin beneficial effects: How the genetic screening in NAFLD patients gains value
17. NR1H4 rs35724 G>C variant modulates liver damage in nonalcoholic fatty liver disease
18. The PSRC1 rs599839 A>G variant disentangles the risk of coronary artery disease and hepatocellular carcinoma in Italian NAFLD patients
19. FXR rs35724 G>C variant modulates cholesterol levels, carotid atherosclerosis and liver damage in non-alcoholic fatty liver
20. TM6SF2 silencing impairs lipid metabolism and trafficking in HepG2 cells carrying the I148M PNPLA3 variant and MBOAT7 deletion
21. Functional characterization of a novel genetic variant predisposing to hepatocellular carcinoma development in nonalcoholic fatty liver disease
22. TM6SF2/PNPLA3/MBOAT7 loss-of-function genetic variants impact on NAFLD development and progression both in patients and in in vitro models
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