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15 results on '"Ruaro, Barbara"'

1. Nailfold Capillaroscopy Analysis Can Add a New Perspective to Biomarker Research in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

Author

Screm, Gianluca, primary, Mondini, Lucrezia, additional, Confalonieri, Paola, additional, Salton, Francesco, additional, Trotta, Liliana, additional, Barbieri, Mariangela, additional, Mari, Marco, additional, Reccardini, Nicolò, additional, Della Porta, Rossana, additional, Kodric, Metka, additional, Bandini, Giulia, additional, Hughes, Michael, additional, Bellan, Mattia, additional, Lerda, Selene, additional, Confalonieri, Marco, additional, and Ruaro, Barbara, additional

Published
2024
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3. Pulmonary Sarcoidosis and Immune Dysregulation: A Pilot Study on Possible Correlation

Author

Cifaldi, Rossella, primary, Salton, Francesco, additional, Confalonieri, Paola, additional, Trotta, Liliana, additional, Barbieri, Mariangela, additional, Ruggero, Luca, additional, Valeri, Gianmaria, additional, Pozzan, Riccardo, additional, Della Porta, Rossana, additional, Kodric, Metka, additional, Baratella, Elisa, additional, Bellan, Mattia, additional, Lerda, Selene, additional, Hughes, Michael, additional, Confalonieri, Marco, additional, Cova, Maria Assunta, additional, Gandin, Ilaria, additional, Mondini, Lucrezia, additional, and Ruaro, Barbara, additional

Published
2023
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8. An Overview of Different Techniques for Improving the Treatment of Pulmonary Hypertension Secondary in Systemic Sclerosis Patients

Author

Ruaro, Barbara, primary, Salton, Francesco, additional, Baratella, Elisa, additional, Confalonieri, Paola, additional, Geri, Pietro, additional, Pozzan, Riccardo, additional, Torregiani, Chiara, additional, Bulla, Roberta, additional, Confalonieri, Marco, additional, Matucci-Cerinic, Marco, additional, and Hughes, Michael, additional

Published
2022
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9. Chronic Thromboembolic Pulmonary Hypertension: An Update

Author

Ruaro, Barbara, primary, Baratella, Elisa, additional, Caforio, Gaetano, additional, Confalonieri, Paola, additional, Wade, Barbara, additional, Marrocchio, Cristina, additional, Geri, Pietro, additional, Pozzan, Riccardo, additional, Andrisano, Alessia Giovanna, additional, Cova, Maria Assunta, additional, Cortale, Maurizio, additional, Confalonieri, Marco, additional, and Salton, Francesco, additional

Published
2022
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10. High-Resolution Computed Tomography and Lung Ultrasound in Patients with Systemic Sclerosis: Which One to Choose?

Author

Ruaro, Barbara, primary, Baratella, Elisa, additional, Confalonieri, Paola, additional, Confalonieri, Marco, additional, Vassallo, Fabio Giuseppe, additional, Wade, Barbara, additional, Geri, Pietro, additional, Pozzan, Riccardo, additional, Caforio, Gaetano, additional, Marrocchio, Cristina, additional, Cova, Maria Assunta, additional, and Salton, Francesco, additional

Published
2021
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11. High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients

Author

Ruaro, Barbara, primary, Baratella, Elisa, additional, Confalonieri, Paola, additional, Wade, Barbara, additional, Marrocchio, Cristina, additional, Geri, Pietro, additional, Busca, Annalisa, additional, Pozzan, Riccardo, additional, Andrisano, Alessia Giovanna, additional, Cova, Maria Assunta, additional, Confalonieri, Marco, additional, and Salton, Francesco, additional

Published
2021
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12. Evaluation of Correlations between Genetic Variants and High-Resolution Computed Tomography Patterns in Idiopathic Pulmonary Fibrosis

Author

Baratella, Elisa, primary, Ruaro, Barbara, additional, Giudici, Fabiola, additional, Wade, Barbara, additional, Santagiuliana, Mario, additional, Salton, Francesco, additional, Confalonieri, Paola, additional, Simbolo, Michele, additional, Scarpa, Aldo, additional, Tollot, Saverio, additional, Marrocchio, Cristina, additional, Cova, Maria Assunta, additional, and Confalonieri, Marco, additional

Published
2021
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13. Correlation between Microvascular Damage and Internal Organ Involvement in Scleroderma: Focus on Lung Damage and Endothelial Dysfunction

Author

Mario D’Oria, Ilaria Gandin, Pozzan Riccardo, Michael Hughes, Sandro Lepidi, Francesco Salton, Paola Confalonieri, Marco Confalonieri, Stefano Tavano, Barbara Ruaro, D'Oria, Mario, Gandin, Ilaria, Pozzan, Riccardo, Michael, Hughe, Lepidi, Sandro, Salton, Francesco, Confalonieri, Paola, Confalonieri, Marco, Tavano, Stefano, and Ruaro, Barbara

Subjects
lung impairment, dermal thickness (DT), lung impairments, peripheral blood perfusion (PBP), systemic sclerosis (SSc), Clinical Biochemistry
Abstract

Background. Systemic sclerosis (SSc) is an incurable connective tissue disease characterized by decreased peripheral blood perfusion due to microvascular damage and skin thickening/hardening. The microcirculation deficit is typically secondary to structural vessel damage, which can be assessed morphologically and functionally in a variety of ways, exploiting different technologies. Objective. This paper focuses on reviewing new studies regarding the correlation between microvascular damage, endothelial dysfunction, and internal organ involvement, particularly pulmonary changes in SSc. Methods. We critically reviewed the most recent literature on the correlation between blood perfusion and organ involvement. Results. Many papers have demonstrated the link between structural microcirculatory damage and pulmonary involvement; however, studies that have investigated correlations between microvascular functional impairment and internal organ damage are scarce. Overall, the literature supports the correlation between organ involvement and functional microcirculatory impairment in SSc patients. Conclusions. Morphological and functional techniques appear to be emerging biomarkers in SSc, but obviously need further investigation.

Published
2022

14. Clinical Evaluation of the ButterfLife Device for Simultaneous Multiparameter Telemonitoring in Hospital and Home Settings

Author

Francesco Salton, Stefano Kette, Paola Confalonieri, Sergio Fonda, Selene Lerda, Michael Hughes, Marco Confalonieri, Barbara Ruaro, Salton, Francesco, Kette, Stefano, Confalonieri, Paola, Fonda, Sergio, Lerda, Selene, Hughes, Michael, Confalonieri, Marco, and Ruaro, Barbara

Subjects
vital parameters, ButterfLife, ECG, artificial intelligence, photoplethysmography, telehealth, telemedicine, Clinical Biochemistry
Abstract

We conducted a two-phase study to test the reliability and usability of an all-in-one artificial intelligence-based device (ButterfLife), which allows simultaneous monitoring of five vital signs. The first phase of the study aimed to test the agreement between measurements performed with ButterfLife vs. standard of care (SoC) in 42 hospitalized patients affected by acute respiratory failure. In this setting, the greatest discordance between ButterfLife and SoC was in respiratory rate (mean difference −4.69 bpm). Significantly close correlations were observed for all parameters except diastolic blood pressure and oxygen saturation (Spearman’s Rho −0.18 mmHg; p = 0.33 and 0.20%; p = 0.24, respectively). The second phase of the study was conducted on eight poly-comorbid patients using ButterfLife at home, to evaluate the number of clinical conditions detected, as well as the patients’ compliance and satisfaction. The average proportion of performed tests compared with the scheduled number was 67.4%, and no patients reported difficulties with use. Seven conditions requiring medical attention were identified, with a sensitivity of 100% and specificity of 88.9%. The median patient satisfaction was 9.5/10. In conclusion, ButterfLife proved to be a reliable and easy-to-use device, capable of simultaneously assessing five vital signs in both hospital and home settings.

Published
2022

15. High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients

Author

Paola Confalonieri, Annalisa Busca, Barbara Wade, Elisa Baratella, Francesco Salton, Barbara Ruaro, Riccardo Pozzan, Marco Confalonieri, Alessia Giovanna Andrisano, Maria Assunta Cova, Pietro Geri, Cristina Marrocchio, Ruaro, Barbara, Baratella, Elisa, Confalonieri, Paola, Wade, Barbara, Marrocchio, Cristina, Geri, Pietro, Busca, Annalisa, Pozzan, Riccardo, Andrisano, Alessia Giovanna, Cova, Maria Assunta, Confalonieri, Marco, and Salton, Francesco

Subjects
Medicine (General), High-resolution computed tomography, medicine.medical_specialty, Clinical Biochemistry, systemic sclerosis (SSc), Review, high-resolution computed tomography (HRTC), Pulmonary function testing, R5-920, Disease severity, systemic sclerosis-associated interstitial lung disease (SSc-ILD), medicine, Intensive care medicine, usual interstitial pneumonia (UIP), Lung, Modalities, medicine.diagnostic_test, business.industry, interstitial lung disease (ILD), Disease progression, Interstitial lung disease, respiratory system, medicine.disease, respiratory tract diseases, First line treatment, pulmonary function tests (PFT), medicine.anatomical_structure, business
Abstract

The diagnosis and classification of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is essential to improve the prognosis of systemic sclerosis (SSc) patients. The risk-stratification of disease severity and follow-up requires a multidisciplinary approach, integrating high-resolution computed tomography (HRTC) of the lung, pulmonary function tests (PFT), along with clinical and symptomatic evaluations. The use of HRCT in detecting SSc-ILD is not so much based on a definitive validation, but rather reflects the widespread clinician recognition of dissatisfaction with other modalities. However, due to the heterogeneity of SSc-ILD and the potential absence of symptoms in early or mild disease, it is prudent to consider as many parameters as possible in the assessment and monitoring of newly diagnosed patients. An early diagnosis meets the primary goal, i.e., the prevention of disease progression. The current first line treatment regimens are mainly centered on immunosuppressive therapy. This review assesses the role HRCT plays in optimizing care and improving clinical outcomes in SSc-ILD patients.

Published
2021

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