1. Evaluation of a rapid antigen detection point-of-care test for respiratory syncytial virus and influenza in a pediatric hospitalized population in the Netherlands
- Author
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Karin van Dijk, Frea Kruisinga, Katja C. Wolthers, Hetty van Eijk, Andrea H. L. Bruning, Dasja Pajkrt, Gerrit Koen, Job B. M. van Woensel, Medical Microbiology and Infection Prevention, CCA - Disease profiling, Graduate School, Other departments, Amsterdam institute for Infection and Immunity, Amsterdam Reproduction & Development (AR&D), Paediatric Intensive Care, Other Research, General Paediatrics, and Paediatric Infectious Diseases / Rheumatology / Immunology
- Subjects
Microbiology (medical) ,Adolescent ,Point-of-Care Systems ,viruses ,Point-of-care testing ,Fluoroimmunoassay ,Population ,Pilot Projects ,Respiratory Syncytial Virus Infections ,Polymerase Chain Reaction ,Sensitivity and Specificity ,Virus ,Antigen ,Influenza, Human ,medicine ,Humans ,False Positive Reactions ,Respiratory system ,Child ,education ,Antigens, Viral ,Respiratory Tract Infections ,Netherlands ,education.field_of_study ,medicine.diagnostic_test ,business.industry ,Infant, Newborn ,Infant ,virus diseases ,Respiratory infection ,Influenza a ,General Medicine ,Virology ,Influenza B virus ,Infectious Diseases ,Influenza A virus ,Child, Preschool ,Respiratory Syncytial Virus, Human ,Immunoassay ,Immunology ,business - Abstract
This pilot study evaluates the diagnostic performance of Sofia RSV Fluorescent Immunoassay Analyzer (FIA) and Sofia Influenza A + B FIA for rapid detection of respiratory syncytial virus and influenza A and B. Sofia had a lower-than-expected sensitivity for all viruses and a high rate of false-positive results for influenza B virus.
- Published
- 2014
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