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129 results on '"Rats, Zucker"'

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1. A novel dual PPAR-γ agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes

2. MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy

3. SHP-1 activation inhibits vascular smooth muscle cell proliferation and intimal hyperplasia in a rodent model of insulin resistance and diabetes

4. ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity

5. Vasopressin and hydration play a major role in the development of glucose intolerance and hepatic steatosis in obese rats

6. In vivo postprandial lipid partitioning in liver and skeletal muscle in prediabetic and diabetic rats

7. Chronic treatment with a glucokinase activator delays the onset of hyperglycaemia and preserves beta cell mass in the Zucker diabetic fatty rat

8. Nuclear factor of activated T cells mediates oxidised LDL-induced calcification of vascular smooth muscle cells

9. Altered gap junctional communication and renal haemodynamics in Zucker fatty rat model of type 2 diabetes

10. Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1 alpha) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats

11. Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats

12. Reduced EDHF responses and connexin activity in mesenteric arteries from the insulin-resistant obese Zucker rat

13. The equivocal metabolic response to endotoxaemia in type 2 diabetic and obese ZDF rats

14. Apolipoprotein AV does not contribute to hypertriglyceridaemia or triglyceride lowering by dietary fish oil and rosiglitazone in obese Zucker rats

15. Dose–response for glycaemic and metabolic changes 28 days after single injection of long-acting release exenatide in diabetic fatty Zucker rats

16. Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition

17. Ischaemic preconditioning does not protect the heart in obese and lean animal models of Type 2 diabetes

18. Renal disease in rats with Type 2 diabetes is associated with decreased renal nitric oxide production

19. Antidiabetic effect of novel modulating peptides of G-protein-coupled kinase in experimental models of diabetes

20. Adipocytes release a soluble form of VAP-1/SSAO by a metalloprotease-dependent process and in a regulated manner

21. The vasopeptidase inhibitor AVE7688 ameliorates Type 2 diabetic nephropathy

22. Differential regulation of glomerular gelatinase B (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in obese Zucker rats

23. Accelerated gastric emptying of glucose in Zucker type 2 diabetic rats: role in postprandial hyperglycaemia

24. Chronic muscle stimulation improves insulin sensitivity while increasing subcellular lipid droplets and reducing selected diacylglycerol and ceramide species in obese Zucker rats

25. Counteracting neuronal nitric oxide synthase proteasomal degradation improves glucose transport in insulin-resistant skeletal muscle from Zucker fa/fa rats

26. Long-term and rapid regulation of ob mRNA levels in adipose tissue from normal (Sprague Dawley rats) and obese [db/db mice, fa/fa rats) rodents

27. Intracerebroventricular administration of neuropeptide Y to normal rats increases obese gene expression in white adipose tissue

28. Effect of adrenalectomy on the development of a pancreatic islet lesion in fa/fa rats

29. Decreased skeletal muscle phosphotyrosine phosphatase (PTPase) activity towards insulin receptors in insulin-resistant Zucker rats measured by delayed Europium fluorescence

30. The pathogenesis of NIDDM: the role of the pancreatic beta cell

31. Caloric restriction in obese pre-diabetic rats prevents beta-cell depletion, loss of beta-cell GLUT 2 and glucose incompetence

32. Induction and reversibility of an obesity syndrome by intracerebroventricular neuropeptide Y administration to normal rats

33. Subcellular lipid droplet distribution in red and white muscles in the obese Zucker rat

34. Increased neuronal nitric oxide synthase dimerisation is involved in rat and human pancreatic beta cell hyperactivity in obesity

35. Increasing skeletal muscle fatty acid transport protein 1 (FATP1) targets fatty acids to oxidation and does not predispose mice to diet-induced insulin resistance

36. Intraglomerular fibronectin accumulation and degradation in obese Zucker rats

37. Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass

38. LR-90 prevents dyslipidaemia and diabetic nephropathy in the Zucker diabetic fatty rat

39. Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions

40. Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 diabetes

41. Gene expression profiling in skeletal muscle of Zucker diabetic fatty rats: implications for a role of stearoyl-CoA desaturase 1 in insulin resistance

42. A novel dual PPAR-γ agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes.

43. Skeletal muscle insulin resistance is induced by 4-hydroxy-2-hexenal, a by-product of n-3 fatty acid peroxidation.

44. α-linolenic acid supplementation prevents exercise-induced improvements in white adipose tissue mitochondrial bioenergetics and whole-body glucose homeostasis in obese Zucker rats.

45. Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition

46. The effect of insulin and exercise on c-Cbl protein abundance and phosphorylation in insulin-resistant skeletal muscle in lean and obese Zucker rats

47. Selective impairment of insulin signalling in the hypothalamus of obese Zucker rats

48. Rab11 is associated with GLUT4-containing vesicles and redistributes in response to insulin

49. Abnormal insulin and beta-adrenergic modulation of lipoprotein liipase during refeeding after prolonged fasting in the Zucker rat

50. Impaired glycogen synthesis in hepatocytes from Zucker fatty fa/fa rats: the role of increased phosphorylase activity

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