1. Insulin pump therapy management in very young children with type 1 diabetes using continuous subcutaneous insulin infusion.
- Author
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Rabbone I, Scaramuzza A, Bobbio A, Bonfanti R, Iafusco D, Lombardo F, Toni S, Tumini S, and Cerutti F
- Subjects
- Age Factors, Child, Preschool, Female, Glycated Hemoglobin metabolism, Humans, Hypoglycemic Agents administration & dosage, Hypoglycemic Agents adverse effects, Insulin adverse effects, Longitudinal Studies, Male, Diabetes Mellitus, Type 1 drug therapy, Insulin administration & dosage, Insulin Infusion Systems adverse effects
- Abstract
Background: Compared to older children and adolescents very young patients with type 1 diabetes represent a unique population. We analyzed the age-dependent characteristics and parameters of continuous subcutaneous insulin infusion (CSII) in children under 6 years of age with type 1 diabetes., Methods: We evaluated metabolic control and pump-dependent characteristics in 46 children with type 1 diabetes after 0.89 +/- 0.62 years of CSII., Results: Metabolic control significantly improved after CSII initiation (glycosylated hemoglobin, 8.12 +/- 1.24% vs. 7.30 +/- 0.67%; P < 0.05), without increased risk for diabetic ketoacidosis or hypoglycemia. Interestingly, very young patients required bigger boluses than expected, especially in the morning and at the afternoon snack., Conclusions: These data support the need to personalize pump-dependent characteristics, especially in very young children with type 1 diabetes, in order to optimize CSII therapy in this unique age group of patients.
- Published
- 2009
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