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13 results on '"Schram, Miranda T."'

1. Fructose Intake From Fruit Juice and Sugar-Sweetened Beverages Is Associated With Higher Intrahepatic Lipid Content: The Maastricht Study

Author

Buziau, Amée M., primary, Eussen, Simone J.P.M., additional, Kooi, M. Eline, additional, van der Kallen, Carla J.H., additional, van Dongen, Martien C.J.M., additional, Schaper, Nicolaas C., additional, Henry, Ronald M.A., additional, Schram, Miranda T., additional, Dagnelie, Pieter C., additional, van Greevenbroek, Marleen M.J., additional, Wesselius, Anke, additional, Bekers, Otto, additional, Meex, Steven J.R., additional, Schalkwijk, Casper G., additional, Stehouwer, Coen D.A., additional, and Brouwers, Martijn C.G.J., additional

Published
2022
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2. Association of Type 2 Diabetes, According to the Number of Risk Factors Within Target Range, With Structural Brain Abnormalities, Cognitive Performance, and Risk of Dementia

Author

van Gennip, April C.E., primary, Stehouwer, Coen D.A., additional, van Boxtel, Martin P.J., additional, Verhey, Frans R.J., additional, Koster, Annemarie, additional, Kroon, Abraham A., additional, Köhler, Sebastian, additional, van Greevenbroek, Marleen M.J., additional, Wesselius, Anke, additional, Eussen, Simone J.P.M., additional, Backes, Walter H., additional, Jansen, Jacobus F., additional, Schram, Miranda T., additional, Henry, Ronald M.A., additional, Singh-Manoux, Archana, additional, and van Sloten, Thomas T., additional

Published
2021
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5. Both Prediabetes and Type 2 Diabetes Are Associated With Lower Heart Rate Variability: The Maastricht Study

Author

Coopmans, Charlotte, primary, Zhou, Tan Lai, additional, Henry, Ronald M.A., additional, Heijman, Jordi, additional, Schaper, Nicolaas C., additional, Koster, Annemarie, additional, Schram, Miranda T., additional, van der Kallen, Carla J.H., additional, Wesselius, Anke, additional, den Engelsman, Robert J.A., additional, Crijns, Harry J.G.M., additional, and Stehouwer, Coen D.A., additional

Published
2020
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7. White Matter Connectivity Abnormalities in Prediabetes and Type 2 Diabetes: The Maastricht Study

Author

Vergoossen, Laura W., primary, Schram, Miranda T., additional, de Jong, Joost J., additional, Stehouwer, Coen D., additional, Schaper, Nicolaas C., additional, Henry, Ronald M., additional, van der Kallen, Carla J., additional, Dagnelie, Pieter C., additional, van Boxtel, Martin P., additional, Eussen, Simone J., additional, Backes, Walter H., additional, and Jansen, Jacobus F., additional

Published
2019
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8. White Matter Connectivity Abnormalities in Prediabetes and Type 2 Diabetes: The Maastricht Study.

Author

Vergoossen, Laura W., Schram, Miranda T., de Jong, Joost J., Stehouwer, Coen D., Schaper, Nicolaas C., Henry, Ronald M., van der Kallen, Carla J., Dagnelie, Pieter C., van Boxtel, Martin P., Eussen, Simone J., Backes, Walter H., and Jansen, Jacobus F.

Abstract

Objective: Prediabetes and type 2 diabetes are associated with structural brain abnormalities, often observed in cognitive disorders. Besides visible lesions, (pre)diabetes might also be associated with alterations of the intrinsic organization of the white matter. In this population-based cohort study, the association of prediabetes and type 2 diabetes with white matter network organization was assessed.Research Design and Methods: In the Maastricht Study, a type 2 diabetes-enriched population-based cohort study (1,361 subjects with normal glucose metabolism, 348 with prediabetes, and 510 with type 2 diabetes assessed by oral glucose tolerance test; 52% men; aged 59 ± 8 years), 3 Tesla structural and diffusion MRI was performed. Whole-brain white matter tractography was used to assess the number of connections (node degree) between 94 brain regions and the topology (graph measures). Multivariable linear regression analyses were used to investigate the associations of glucose metabolism status with network measures. Associations were adjusted for age, sex, education, and cardiovascular risk factors.Results: Prediabetes and type 2 diabetes were associated with lower node degree after full adjustment (standardized [st]βPrediabetes = -0.055 [95% CI -0.172, 0.062], stβType2diabetes = -0.256 [-0.379, -0.133], Ptrend < 0.001). Prediabetes was associated with lower local efficiency (stβ = -0.084 [95% CI -0.159, -0.008], P = 0.033) and lower clustering coefficient (stβ = -0.097 [95% CI -0.189, -0.005], P = 0.049), whereas type 2 diabetes was not. Type 2 diabetes was associated with higher communicability (stβ = 0.148 [95% CI 0.042, 0.253], P = 0.008).Conclusions: These findings indicate that prediabetes and type 2 diabetes are associated with fewer white matter connections and weaker organization of white matter networks. Type 2 diabetes was associated with higher communicability, which was not yet observed in prediabetes and may reflect the use of alternative white matter connections. [ABSTRACT FROM AUTHOR]

Published
2020
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9. Prediabetes Is Associated With Structural Brain Abnormalities: The Maastricht Study

Author

van Agtmaal, Marnix J.M., primary, Houben, Alfons J.H.M., additional, de Wit, Vera, additional, Henry, Ronald M.A., additional, Schaper, Nicolaas C., additional, Dagnelie, Pieter C., additional, van der Kallen, Carla J., additional, Koster, Annemarie, additional, Sep, Simone J., additional, Kroon, Abraham A., additional, Jansen, Jacobus F.A., additional, Hofman, Paul A., additional, Backes, Walter H., additional, Schram, Miranda T., additional, and Stehouwer, Coen D.A., additional

Published
2018
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10. High Diabetes Distress Among Ethnic Minorities Is Not Explained by Metabolic, Cardiovascular, or Lifestyle Factors: Findings From the Dutch Diabetes Pearl Cohort

Author

Özcan, Behiye, primary, Rutters, Femke, additional, Snoek, Frank J., additional, Roosendaal, Mandy, additional, Sijbrands, Eric J., additional, Elders, Petra J.M., additional, Holleman, Frits, additional, Pijl, Hanno, additional, Tack, Cees J., additional, Abbink, Evertine J., additional, de Valk, Harold W., additional, Wolffenbuttel, Bruce H.R., additional, Stehouwer, Coen D.A., additional, Schaper, Nicholas C., additional, Dekker, Jacqueline M., additional, and Schram, Miranda T., additional

Published
2018
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11. Social Network Characteristics Are Associated With Type 2 Diabetes Complications: The Maastricht Study

Author

Brinkhues, Stephanie, primary, Dukers-Muijrers, Nicole H.T.M., additional, Hoebe, Christian J.P.A., additional, van der Kallen, Carla J.H., additional, Koster, Annemarie, additional, Henry, Ronald M.A., additional, Stehouwer, Coen D.A., additional, Savelkoul, Paul H.M., additional, Schaper, Nicolaas C., additional, and Schram, Miranda T., additional

Published
2018
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12. The Role of Hyperglycemia, Insulin Resistance, and Blood Pressure in Diabetes-Associated Differences in Cognitive Performance—The Maastricht Study

Author

Geijselaers, Stefan L.C., primary, Sep, Simone J.S., additional, Claessens, Danny, additional, Schram, Miranda T., additional, van Boxtel, Martin P.J., additional, Henry, Ronald M.A., additional, Verhey, Frans R.J., additional, Kroon, Abraham A., additional, Dagnelie, Pieter C., additional, Schalkwijk, Casper G., additional, van der Kallen, Carla J.H., additional, Biessels, Geert Jan, additional, and Stehouwer, Coen D.A., additional

Published
2017
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13. Hyperglycemia Is the Main Mediator of Prediabetes- and Type 2 Diabetes–Associated Impairment of Microvascular Function: The Maastricht Study

Author

Sörensen, Ben M., primary, Houben, Alfons J.H.M., additional, Berendschot, Tos T.J.M., additional, Schouten, Jan S.A.G., additional, Kroon, Abraham A., additional, van der Kallen, Carla J.H., additional, Henry, Ronald M.A., additional, Koster, Annemarie, additional, Reesink, Koen D., additional, Dagnelie, Pieter C., additional, Schaper, Nicolaas C., additional, Schalkwijk, Casper G., additional, Schram, Miranda T., additional, and Stehouwer, Coen D.A., additional

Published
2017
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