1. Results From a European Multicenter Randomized Trial of Physical Activity and/or Healthy Eating to Reduce the Risk of Gestational Diabetes Mellitus: The DALI Lifestyle Pilot
- Author
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David Hill, André Van Assche, Juan M. Adelantado, Lise Lotte Torvin Andersen, Dorte Møller Jensen, Jürgen Harreiter, Gernot Desoye, Frank J. Snoek, Goele Jans, Mireille N M van Poppel, Sander Galjaard, Elisabeth R. Mathiesen, Agnieszka Zawiejska, Rosa Corcoy, Judith G. M. Jelsma, Annunziata Lapolla, Alexandra Kautzky-Willer, Alessandra Bertolotto, Ewa Wender-Ozegowska, P. Rebollo, Roland Devlieger, Maria Grazia Dalfrà, Peter Damm, Fidelma Dunne, David Simmons, Public and occupational health, Medical psychology, EMGO - Lifestyle, overweight and diabetes, and Medical Psychology
- Subjects
Endocrinology, Diabetes and Metabolism ,Pilot Projects ,Overweight ,outcomes ,Weight Gain ,law.invention ,lip ,Endocrinology ,Randomized controlled trial ,prevention ,law ,Pregnancy ,Adult ,Diabetes, Gestational ,Europe ,Feeding Behavior ,Female ,Glucose Tolerance Test ,Humans ,Insulin Resistance ,Motivational Interviewing ,Obesity ,Life Style ,Motor Activity ,Risk Reduction Behavior ,Internal Medicine ,Advanced and Specialized Nursing ,Medicine (all) ,obese pregnant-women ,fasting plasma-glucose ,intervention ,Glucose tolerance test ,medicine.diagnostic_test ,exercise ,Obstetrics ,Diabetes ,Gestational diabetes ,Diabetes and Metabolism ,Gestational ,medicine.symptom ,metaanalysis ,medicine.medical_specialty ,Insulin resistance ,Diabetes mellitus ,medicine ,overweight ,business.industry ,weight ,medicine.disease ,Physical therapy ,business ,Weight gain - Abstract
OBJECTIVE Ways to prevent gestational diabetes mellitus (GDM) remain unproven. We compared the impact of three lifestyle interventions (healthy eating [HE], physical activity [PA], and both HE and PA [HE+PA]) on GDM risk in a pilot multicenter randomized trial. RESEARCH DESIGN AND METHODS Pregnant women at risk for GDM (BMI ≥29 kg/m2) from nine European countries were invited to undertake a 75-g oral glucose tolerance test before 20 weeks' gestation. Those without GDM were randomized to HE, PA, or HE+PA. Women received five face-to-face and four optional telephone coaching sessions, based on the principles of motivational interviewing. A gestational weight gain (GWG) RESULTS Among the 150 trial participants, 32% developed GDM by 35–37 weeks and 20% achieved GWG CONCLUSIONS An antenatal HE intervention is associated with less GWG and lower fasting glucose compared with PA alone. These findings require a larger trial for confirmation but support the use of early HE interventions in obese pregnant women.
- Published
- 2015