1. Association of Vaspin with Metabolic Syndrome: The Pivotal Role of Insulin Resistance
- Author
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Alireza Esteghamati, Sina Noshad, Mostafa Mousavizadeh, Ali Zandieh, and Manouchehr Nakhjavani
- Subjects
Abdominal obesity ,Inflammation ,Insulin resistance ,Metabolic syndrome ,Vaspin ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
BackgroundPrevious studies evaluating the relationship between serum vaspin concentrations and metabolic syndrome (MetS) have yielded contrasting results. Additionally, contribution of general and abdominal obesity, chronic inflammation, and insulin resistance to this relationship remains unknown.MethodsIn a cross-sectional setting, we investigated the association between vaspin and MetS in 145 subjects ranging from normoglycemia to type 2 diabetes. Vaspin concentrations were measured using enzyme-linked immunosorbent assay.ResultsWomen had 29% higher vaspin concentrations compared with men. Subjects with MetS (51% of all participants) had higher vaspin concentrations (P=0.019 in women and P
- Published
- 2014
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