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1. Prohormone convertase 1 in obesity, gestational diabetes mellitus, and NIDDM: no evidence for a major susceptibility role.

Author

Kalidas, Kamini, Dow, Eleanor, Saker, Philip J., Wareham, Nicholas, Halsall, David, Jackson, Robert S., Chan, Siew-Pheng, Gelding, Susan, Walker, Mark, Kousta, Eleni, Johnston, Desmond G., O'Rahilly, Stephen, McCarthy, Mark I., Kalidas, K, Dow, E, Saker, P J, Wareham, N, Halsall, D, Jackson, R S, and Chan, S P

Subjects
GENETICS of type 2 diabetes, OBESITY genetics, CHROMOSOMES, COMPARATIVE studies, GESTATIONAL diabetes, GENE mapping, GENETIC polymorphisms, GENETICS, HUMAN constitution, RESEARCH methodology, MEDICAL cooperation, TYPE 2 diabetes, OBESITY, POLYMERASE chain reaction, PROTEOLYTIC enzymes, RESEARCH, GENETIC markers, EVALUATION research, BODY mass index, GENOTYPES
Abstract

Studies the primary molecular events underlying non-insulin dependent diabetes (NIDDM) and obesity. Individual susceptibility to interrelated conditions under genetic influence; Processing of proinsulin to mature insulin; Evidence for linkage between the gene region and NIDDM.

Published
1998
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