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The aim is to find skarn polymetallic deposits more accurately. Firstly, the mineralogical and mineral chemical characteristics of garnet are analyzed and studied. Then, the typical skarn deposit is analyzed by means of electron probe, laser inductively coupled plasma mass spectrometry and the mathematical model of rock salt water solution mining. The results show that garnet is one of the main minerals in the skarn polymetallic deposit, and its shape is beneficial to the stability of the roof of the solution cavity. The dissolution rate around the injection well is about 2~3 times that around the outlet well. With the extension of the dissolution and production time, the dissolution rate of the rock salt layer in the whole dissolution chamber decreases. After nearly 100 h of dissolution and production, the dissolution rate around the outlet well is almost zero. The dissolution rate around the injection well decreased to less than 0.1 cm/h. SiO2content is generally around 35%, and gradually increases during the formation of the deposit. According to the characteristics of garnet, the polymetallic content and deposit type of skarn deposit are analyzed and calculated, so as to determine the value of skarn deposit. This exploration is of great significance to the prospecting behavior of skarn polymetallic deposit.