1. Rhino-orbito-cerebral mucormycosis: report of two cases and review of the literature.
- Author
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Haliloglu NU, Yesilirmak Z, Erden A, and Erden I
- Subjects
- Adrenal Cortex Hormones therapeutic use, Amphotericin B therapeutic use, Antifungal Agents therapeutic use, Diabetes Complications, Diabetes Mellitus, Type 1 complications, Humans, Iatrogenic Disease, Immunocompromised Host, Male, Middle Aged, Purpura, Thrombocytopenic, Idiopathic drug therapy, Brain Diseases microbiology, Mucormycosis diagnosis, Nose Diseases microbiology, Opportunistic Infections diagnosis, Orbital Diseases microbiology
- Abstract
Rhino-orbito-cerebral mucormycosis (ROCM) is a rare, fulminant opportunistic fungal infection that is mostly seen in immunocompromised or diabetic patients. The disease should be recognised and treated immediately. We present here MR imaging findings of two patients with histopathologically proven ROCM. One of the cases had a history of corticosteroid treatment and iatrogenic diabetes mellitus and although amphotericin B was started immediately, the disease progressed and surgical debridement was necessary. The second case was a patient with diabetes mellitus type 1 in whom ROCM had occurred following an abdominal surgery; amphotericin B treatment alone was adequate in this patient.
- Published
- 2008
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