1. Antibacterial effect and cytocompatibility of nano-structured TiO2 film containing Cl
- Author
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Kyoung Nam Kim, Kwang Mahn Kim, Min-Kyung Kang, and Seung-Kyun Moon
- Subjects
Materials science ,Surface Properties ,chemistry.chemical_element ,Nanotechnology ,Microbial Sensitivity Tests ,Sodium Chloride ,Bacterial Adhesion ,Streptococcus mutans ,Contact angle ,chemistry.chemical_compound ,Hydrofluoric acid ,Cell Line, Tumor ,Materials Testing ,Nano ,Humans ,MTT assay ,General Dentistry ,Cell Proliferation ,Dental Implants ,Titanium ,Osteoblasts ,Anodizing ,technology, industry, and agriculture ,Adhesion ,Anti-Bacterial Agents ,chemistry ,Wettability ,Ceramics and Composites ,Wetting ,Nuclear chemistry - Abstract
The aim of this study was to investigate the antibacterial effect and cytocompatibility of a nano-structured TiO2 film that contained Cl and had been coated onto commercially pure titanium. First, we prepared nano-structured TiO2 by anodization with hydrofluoric acid. Then, to confer an antibacterial effect, we performed a second anodization with NaCl solutions of different concentrations (0.5 M, 1 M, 2 M). The morphology, composition, and wettability of the surface were investigated by SEM, EDS, and a video contact angle measuring system. The antibacterial effect was evaluated by film adhesion method. And cytotoxicity was determined by the viability of MG-63 cells in a MTT assay. The SEM and EDS results showed that the TiO2 nano-structure containing Cl had successfully formed after the second anodization. The contact angle analysis showed that the anodized titanium had a hydrophilic character. The results of this in vitro investigation demonstrated that the TiO2 nano-structure film anodized in 1 M NaCl had an antibacterial effect and good cell compatibility.
- Published
- 2011