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We report on a direct and autonomous measure of new production based on time series observations with ISUS nitrate sensors deployed for several years on oceanographic moorings offshore of Monterey Bay, California. The amplitude of diel cycles of surface nitrate is correlated with rates of primary production measured by 14C uptake. The drawdown of nitrate averaged over a year is about 70% of the fixed nitrogen needed for biomass production. Phytoplankton biomass predicted from the diel nitrate uptake and a fixed rate constant for nitrate loss (grazing and export) matched observations over the annual cycle. New production rates determined with the moored sensors are highly correlated with nitrate concentration and the intensity of upwelling. The implication is that arrays of moorings with chemical sensors can now be used to estimate new production of biomass and ecosystem processes over multiple temporal and spatial scales.