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1. Data in support of quantitative proteomics to identify potential virulence regulators in Paracoccidioides brasiliensis isolates

Author

Alexandre Keiji Tashima, Daniele Gonçalves Castilho, Alison Felipe Alencar Chaves, Patricia Xander, André Zelanis, and Wagner Luiz Batista

Subjects
Paracoccidioides brasiliensis, Pathogenic fungus, Proteomic analysis, Virulence factors, Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390
Abstract

Paracoccidioides genus are the etiologic agents of paracoccidioidomycosis (PCM), a systemic mycosis endemic in Latin America. Few virulence factors have been identified in these fungi. This paper describes support data from the quantitative proteomics of Paracoccidioides brasiliensis attenuated and virulent isolates [1]. The protein compositions of two isolates of the Pb18 strain showing distinct infection profiles were quantitatively assessed by stable isotopic dimethyl labeling and proteomic analysis. The mass spectrometry and the analysis dataset have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with identifier PXD000804.

Published
2015
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