1. Data highlighting phenotypic diversity of urine-associated Escherichia coli isolates
- Author
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Allison R. Eberly, Connor J. Beebout, Ching Man Carmen Tong, Gerald T. Van Horn, Hamilton D. Green, Madison J. Fitzgerald, Shuvro De, Emily K. Apple, Alexandra C. Schrimpe-Rutledge, Simona G. Codreanu, Stacy D. Sherrod, John A. McLean, Douglass B. Clayton, Charles W. Stratton, Jonathan E. Schmitz, and Maria Hadjifrangiskou
- Subjects
Asymptomatic bacteriuria ,Biofilm ,Cystitis ,Metabolomics ,Urinary tract infection ,Uropathogenic Escherichia coli ,Computer applications to medicine. Medical informatics ,R858-859.7 ,Science (General) ,Q1-390 - Abstract
This article provides a reusable dataset describing detailed phenotypic and associated clinical parameters in n=303 clinical isolates of urinary Escherichia coli collected at Vanderbilt University Medical Center. De-identified clinical data collected with each isolate are detailed here and correlated to biofilm abundance and metabolomics data. Biofilm-abundance data were collected for each isolate under different in vitro conditions along with datasets quantifying biofilm abundance of each isolate under different conditions. Metabolomics data were collected from a subset of bacterial strains isolated from uncomplicated cases of cystitis or cases with no apparent symptoms accompanying colonization. For more insight, please see “Defining a Molecular Signature for Uropathogenic versus Urocolonizing Escherichia coli: The Status of the Field and New Clinical Opportunities” [1].
- Published
- 2020
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