1. A new approach to the ferritin iron core growth: influence of the H/L ratio on the core shape
- Author
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J.D. López-Castro, José A. Pérez-Omil, Richard Watt, Natividad Gálvez, José M. Domínguez-Vera, Rafael Cuesta, and Juan José Delgado
- Subjects
Models, Molecular ,biology ,Chemistry ,Iron ,Ferritin iron ,law.invention ,Inorganic Chemistry ,Ferritin ,Core (optical fiber) ,Microscopy, Electron ,Protein Subunits ,Crystallography ,Protein structure ,law ,Ferritins ,Microscopy ,biology.protein ,Recombinant DNA ,Humans ,Protein Multimerization ,Electron microscope ,Protein Structure, Quaternary ,H l ratio - Abstract
An electron microscopy study, in combination with modeling and image simulation, of four different reconstituted ferritin samples: recombinant human H and L homopolymers, and H and L heteropolymers of native L-subunit-rich horse spleen and H-subunit-rich human heart ferritins, points out the existence of a correlation between iron core shape and protein shell.
- Published
- 2012
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