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Start Over Author "M. G. Manz" Journal current topics in microbiology and immunology
1 results on '"M. G. Manz"'

1. Human T cell development and HIV infection in human hemato-lymphoid system mice

Author

S, Baenziger, P, Ziegler, L, Mazzucchelli, L, Bronz, R F, Speck, and M G, Manz

Subjects
DNA-Binding Proteins, Disease Models, Animal, Mice, T-Lymphocytes, Hematopoietic Stem Cell Transplantation, Animals, Humans, HIV Infections, Mice, SCID, Hematopoiesis, Interleukin Receptor Common gamma Subunit
Abstract

Advances in generation of mice that on human hematopoietic stem and progenitor cell transplantation develop and maintain human hemato-lymphoid cells have fueled an already thriving field of research. We focus here on human T cell development and HIV infection in Rag2 -/- gamma(c) -/- mice transplanted as newborns with human CD34+ cord blood hematopoietic stem and progenitor cells.

Published
2008

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