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Start Over Author "Fumio Sugata" Journal current therapeutic research
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1. Ursodeoxycholic acid therapy for chronic type C hepatitis: A multicenter, dose-finding trial

Author

Hidenori Ohki, Makoto Kako, Makoto Yoshiba, Hiroshi Nakajima, Kazunori Matsumoto, Tohru Narita, Fumio Sugata, Kazuo Kamii, Kazuhiko Miyake, Masami Yamanaka, Kazuhiko Sekiyama, Toshio Aoyagi, and Hajime Takikawa

Subjects
Pharmacology, Hepatitis, medicine.medical_specialty, business.industry, Hepatitis A, medicine.disease, Gastroenterology, Ursodeoxycholic acid, Surgery, Dose finding, Internal medicine, medicine, Pharmacology (medical), Alanine aminotransferase, business, medicine.drug
Abstract

Ursodeoxycholic acid (UDCA) was administered orally for 12 weeks to 40 patients with chronic type C hepatitis. Patients were randomly assigned to receive UDCA 150 mg/day (n = 20) or 450 mg/day (n = 20). In the 450-mg group, alanine aminotransferase (ALT) decreased significantly ( P P P P

Published
1994
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