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In the rapidly expanding field of nanoscience and research, AgNPs and their diverse by-products have been acknowledged as having a green approach. Fruit extract of Limonia acidissimais capable of bio-reducing AgNO3and stabilizing AgNPs. AgNPs distinctive absorption peak at 417 nm at pH 8 was visible on the UV-Vis spectrophotometer. The fruit extract contained bioactive chemicals, which may be the cause of the AgNPs bio-capping and stabilizing properties, according to Fourier transform infrared (FT-IR) spectroscopy. Using an X-ray diffractometer (XRD) examination, the AgNPs solid crystalline nature and size of 29.05 nm were investigated. Lastly, AFM and HR-TEM studies verified the AgNPs surface morphology, particularly their size and form. The DPPH assay method was used to measure the AgNPs capacity for radical scavenging. As compared to normal ascorbic acid and fruit extract (control), the AgNPs produced from the fruit extract demonstrated good antioxidant effectiveness. To evaluate the antibacterial activity of the AgNPs sample, it was additionally evaluated against E. coli, S. typhi, V. cholera,and S. aureus. With the greatest zone of inhibition and thus the strongest antibacterial activity, S. aureus(12.03 ± 0.043 mm) was the organism that displayed it. On the other hand, the least active strain was V. cholera(9.09 ± 0.013 mm). The data indicates that bio-fabricated silver nanoparticles (AgNPs) exhibited dose-dependent inhibitory efficacy together with a notable zone of inhibition. Additionally, S. aureuswas shown to be more effective than V. cholera. Future health and pharmaceutical fields may benefit from the biocompatible method of separating AgNPs from L. acidissimafruit extract.

Manganese oxide nanoparticles (MnO2NPs) were synthesized through a simple one-pot green synthesis method using Saraca asocaleaves extract (SA-MnO2NPs), and their physicochemical properties were characterized using various analytical techniques, including electron microscopy (FESEM and TEM), X-ray diffraction (XRD), and electron diffracted X-ray spectroscopy (EDAX). The as-synthesized MnO2NPs had a highly crystalline structure with a calculated crystalline size of approximately 18 nm and a d-spacing value of 0.216 nm. The morphology of the SA-MnO2NPs was like stacked cubes with high elemental purity, as confirmed by the EDAX spectrum. Further, confirming the as-obtained crystalline size and d-spacing value from the XRD analysis, the samples were subjected to anti-cancer activities to evaluate their reactance against cancer cell lines. The in vitro anti-cancer activity of the synthesized material was assessed against two breast cancer cell lines, namely MCF7 and MDA-MB-231. The results showed that SA-MnO2NPs exhibited significantly lower levels of cytotoxicity against these cell lines, indicating their potential as an effective anticancer agent. Further, the IC50value of SA-MnO2NPs at 24 h was greater than 20 μg/mL. Therefore, the synthesized SA-MnO2NPs could be a promising candidate for developing novel breast cancer treatment therapies.