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1. Preventing cognitive decline in preclinical Alzheimer's disease.

Author

Riedel, Wim J

Subjects
*COGNITION disorders, *ALZHEIMER'S disease, *CEREBROSPINAL fluid, *MORTALITY, *MILD cognitive impairment, *THERAPEUTICS
Abstract

Highlights: [•] Preclinical Alzheimer's disease is common and can be diagnosed by CSF markers. [•] Preclinical AD and future cognitive decline and mortality are strongly associated. [•] Delay of onset of cognitive impairment in preclinical AD is a therapeutic target. [•] Subtle cognitive deficits can be remotely assessed using modern digital platforms. [•] A public–private collaborative approach may be required for AD prevention trials. [ABSTRACT FROM AUTHOR]

Published
2014
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