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Start Over Author "Zhang, Wenjun" Search Limiters Peer Reviewed Topic biosynthesis Journal current opinion in biotechnology

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1 results on '"Zhang, Wenjun"'

1. Engineering modular polyketide synthases for production of biofuels and industrial chemicals.

Author

Cai, Wenlong and Zhang, Wenjun

Subjects
*POLYKETIDE synthases, *POLYKETIDES, *CHEMICAL synthesis, *BIOSYNTHESIS, *DRUG development, *BIOMASS energy
Abstract

Polyketide synthases (PKSs) are one of the most profound biosynthetic factories for producing polyketides with diverse structures and biological activities. These enzymes have been historically studied and engineered to make un-natural polyketides for drug discovery, and have also recently been explored for synthesizing biofuels and industrial chemicals due to their versatility and customizability. Here, we review recent advances in the mechanistic understanding and engineering of modular PKSs for producing polyketide-derived chemicals, and provide perspectives on this relatively new application of PKSs. [ABSTRACT FROM AUTHOR]

Published
2018
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