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Your search keyword '"Bahmad, Hisham F."' showing total 5 results
Start Over Author "Bahmad, Hisham F." Journal current oncology
5 results on '"Bahmad, Hisham F."'

1. Unraveling the Mysteries of Perineural Invasion in Benign and Malignant Conditions

Author

Bahmad, Hisham F., primary, Gogola, Samantha, additional, Rejzer, Michael, additional, Stoyanov, Kalin, additional, Gomez, Aaron S., additional, Valencia, Ann-Katrin, additional, Cummings, Adonicah, additional, Skerry, Timothy, additional, Alloush, Ferial, additional, Aljamal, Abed A., additional, Deb, Arunima, additional, Alghamdi, Sarah, additional, and Poppiti, Robert, additional

Published
2023
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5. Repurposed Effect of 177 Lu-DOTATATE in the Treatment of Mantle Cell Lymphoma.

Author

Elajami, Mohamad K., Burton, Lorena P., Bahmad, Hisham F., Chaaya, Gerard, and Schwartz, Michael

Subjects
MANTLE cell lymphoma, CARCINOID, CARCINOGENESIS, SOMATOSTATIN, LUNG tumors
Abstract

Mantle cell lymphoma (MCL) is an uncommon subcategory of non-Hodgkin lymphoma (NHL). Pathogenesis primarily includes overexpression of CCND1 and SOX11 along with other molecular aberrations. Lutetium 177Lu-DOTATATE is a radiolabeled somatostatin analogue used for the treatment of gastrointestinal neuroendocrine tumors. There are no clinical data supporting the use of Lutetium 177Lu-DOTATATE in the treatment of lymphoma. We describe the case of an 84-year-old man with a history of MCL and carcinoid tumor of the lung. Following progression of the carcinoid malignancy, the patient was treated with Lutetium 177Lu-DOTATATE. After treatment, there was an overall improvement of the patient's MCL that was demonstrated by stable lymphadenopathy on serial CT scans and down-trend of the absolute lymphocyte count. Therefore, we hypothesize that 177Lu-DOTATATE might have a role and can be repurposed for treating MCL. [ABSTRACT FROM AUTHOR]

Published
2022
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