1. Multiparametric Magnetic Resonance Imaging in Pulmonary Hypertension
- Author
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Guilhem Collier, Tom Sproson, Laura C. Saunders, David G. Kiely, Andrew J. Swift, Helen Marshall, Jim M. Wild, and Nehal Hussain
- Subjects
medicine.medical_specialty ,Histology ,medicine.diagnostic_test ,business.industry ,Vascular disease ,Magnetic resonance imaging ,Interventional radiology ,Cell Biology ,medicine.disease ,Applied Microbiology and Biotechnology ,Pulmonary hypertension ,medicine.anatomical_structure ,Afterload ,Ventricle ,Internal medicine ,Cardiology ,Medicine ,Radiology ,business ,Perfusion ,Multiparametric Magnetic Resonance Imaging - Abstract
Quantitative magnetic resonance imaging provides a comprehensive and non-invasive assessment of the heart and lungs in patients with suspected pulmonary hypertension with the potential for accurate assessment of disease severity and response to treatment. Magnetic resonance imaging (MRI) can provide detailed reliable information of heart structure and function as the heart responds to elevated right ventricle afterload in patients with progressive pulmonary vascular disease; notably, progressive changes in right ventricle volume and function are of prognostic value independent of established biomarkers. This article reviews the current literature on MRI in pulmonary hypertension and also describes new and exciting developments in imaging of the heart, pulmonary vasculature and lungs, including assessment of myocardial changes with late gadolinium-enhanced imaging and T1 mapping, evaluating changes in the proximal pulmonary vasculature using image-based computational modelling and quantitative assessment of the capillary bed using MRI perfusion analysis.
- Published
- 2015
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