1. Genome Biology: The Sleek and Oh-So Chic Oxytricha Nanochromosomes
- Author
-
Douglas L. Chalker and Scott A. Horrell
- Subjects
Genetics ,Oxytricha ,Agricultural and Biological Sciences(all) ,biology ,Biochemistry, Genetics and Molecular Biology(all) ,Somatic cell ,Genes, Protozoan ,Gene Dosage ,Genomics ,biology.organism_classification ,Genome ,Chromosomes ,General Biochemistry, Genetics and Molecular Biology ,Gene Frequency ,Genetic linkage ,Macronucleus ,Genome Biology ,Oxytricha trifallax ,Copy-number variation ,General Agricultural and Biological Sciences ,Genome, Protozoan ,Allele frequency - Abstract
Summary The somatic nucleus of Oxytricha trifallax contains over 15,000 different chromosomes, most containing a single gene. Analysis of this 50 Mb genome uncovers novel regulatory strategies and adaptive potential when gene copy number and allelic frequency are no longer constrained by genetic linkage.
- Full Text
- View/download PDF