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Objective: The present study aimed to assess parental knowledge and awareness of early orthodontic consultation in children., Methods: This cross-sectional study was conducted among parents of schoolchildren who were randomly selected from public schools in the Al Ahsa region of Saudi Arabia, using a convenience sampling technique. Data were collected using a prevalidated, pretested study questionnaire distributed to parents through the schoolchildren. The questionnaire focused on the demographic data, knowledge, and awareness of parents regarding their children's need for orthodontic consultation. Descriptive statistics and the Chi-square test were used to analyze the quantitative data collected., Results: More than 50% of the study participants exhibited a good perception of most of the aspects of early orthodontic consultation in children. However, only 42.8% of study subjects exhibited awareness of space maintainers and their use in a growing child, while only 37.5% knew that the first orthodontic visit should be at seven years of age. The age of the participants as well as their educational level were found to be important demographic factors influencing knowledge and awareness of the need for early orthodontic consultation (p<0.05)., Conclusion: The present study found that there were knowledge and awareness gaps among Saudi parents regarding early orthodontic consultation, including those on the need for space maintainers and the age of initial orthodontic consultation. There exists a need for a targeted focus on creating awareness amongst younger and lesser-educated parents, which can largely improve the awareness pertaining to early orthodontic treatment initiation in children., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Ethical Research Committee, Deanship of Scientific Research, King Faisal University issued approval KFU-2024-ETHICS2817. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Mohammed Alwusaybie et al.)

Background Diabetic nephropathy, a leading cause of end-stage renal disease (ESRD), plays a part in the critical healthcare burden globally, especially in Saudi Arabia, where the prevalence of diabetes cases is among the highest worldwide. This study aims to assess the awareness, knowledge, attitudes, and practices (A-KAP) in relation to diabetic nephropathy among the general population in Hafr Al Batin, Saudi Arabia. Methods A cross-sectional study was conducted between January and September 2024, involving 406 participants with a minimum age range of 18 years and older. Data were collected using a self-administered questionnaire, disseminated through social media platforms, i.e., WhatsApp and Facebook, and analyzed using IBM SPSS Statistics for Windows, Version 28.0 (Released 2021; IBM Corp., Armonk, New York, United States). The chi-squared test, Fisher's exact test, and logistic regression analyses were performed to examine the associations between demographic variables and A-KAP scores, with a p≤0.05. Results Of the participants, 53.7% were male, and the largest age group was 20-29 years old (46.8%). The results revealed significant associations between knowledge scores and gender (p=0.033), age (p=0.012), and BMI (p=0.002). Females and participants aged 40-49 years had higher knowledge scores. Furthermore, 58.4% of participants were unaware of their BMI, and those with higher BMI scores showed lower knowledge levels. Regarding attitudes, older participants (aged 40 and above) have demonstrated more positive attitudes toward diabetic nephropathy (p=0.02). Practices related to nephropathy screening were deficient, with 84.2% of participants having never been screened and 68.7% never checking their kidney function. A significant proportion of participants, specifically 71.2%, indicated a lack of regular engagement in physical exercise, highlighting a notable prevalence of physical inactivity. Conclusion This study reveals notable differences in awareness, perceptions, and behaviors related to diabetic nephropathy among the general population in Hafr Al Batin, Saudi Arabia. Females, individuals aged 40-49 years, and participants with lower BMI exhibited higher knowledge scores, while health maintenance practices such as nephropathy screening and kidney function checks were predominantly inadequate. Public health initiatives ought to prioritize enhancing awareness, advocating for regular screening, and fostering physical activity to reduce the risk of diabetic nephropathy. Future research should focus on identifying and overcoming the obstacles to healthcare access and preventive services for this population., Competing Interests: Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Ethical Committee of the University of Hafr Al Batin issued approval HPO-05-FT-24-06. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Ahmad et al.)

Background ENT disorders are common, leading many people to seek medical advice. A common misconception among the population is that upper respiratory tract viral infections can be treated with antibiotics, despite their ineffectiveness against viruses. Assessing the level of knowledge and awareness regarding common ENT-related issues among the population in the Qassim region is therefore crucial. Methods We conducted a cross-sectional study using a random sampling technique to survey 415 participants aged 18 and above. Data were collected through an online self-administered questionnaire and analyzed using SPSS version 26 (IBM Corp., Armonk, NY, USA). The questionnaire assessed participants' knowledge of various ENT issues, and scores were calculated to gauge overall awareness. Results The majority of participants demonstrated a satisfactory level of knowledge, with a mean knowledge score of 9.37 ± 3.59. Significant gender differences were observed, with females displaying higher knowledge levels (61.9%, p < 0.05). Additionally, higher educational attainment was positively correlated with better awareness of ENT issues. Conclusion While general awareness of ENT-related issues in the Qassim region is adequate, specific knowledge gaps remain, particularly regarding the treatment of viral infections. Targeted educational initiatives are needed to address these gaps, focusing on groups with lower awareness levels., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Regional Research Ethics Committee, Qassim Province issued approval 607/45/16889. We are pleased to inform you that your research proposal has been approved by the local ethics committee. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alenezi et al.)

Introduction: Pancreatitis, characterized by abdominal pain and elevated pancreatic enzymes, remains a significant public health issue. This study aims to assess the awareness of the general population in the Eastern Province of Saudi Arabia regarding pancreatitis, focusing on symptoms, risk factors, and management., Methodology: A cross-sectional study was conducted using a structured questionnaire distributed to 446 participants through social media. Data were analyzed using descriptive statistics and Chi-square tests., Results: The study revealed that the most recognized symptoms of pancreatitis were abdominal pain, nausea, and vomiting. High-fat diets and genetic factors were the most commonly acknowledged risk factors. Medications and dietary changes were the most frequently known treatment methods. The overall knowledge level was 46%, with a significant difference in knowledge between healthcare and non-healthcare personnel. However, there were no significant differences in knowledge based on gender or income levels., Conclusion: The study highlights a considerable gap in public awareness of pancreatitis, emphasizing the need for targeted educational initiatives. Enhanced public health campaigns could improve early detection and management, potentially reducing the disease burden in Saudi Arabia., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Research Ethics Committee at King Faisal University issued approval KFU-REC-2024-SEP- ETHICS2545. The Chair of the Research Ethics Committee at King Faisal University grants its ethical approval to the protocol. Projects may be subject to an audit or any other form of monitoring by the committee at any time. The committee may request a regular report on the progress of the project to ensure that researchers are committed to the highest ethical standards. Researchers are held accountable for the storage, retention, and security of original data obtained from projects. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alnami et al.)

Background Basic life support (BLS) is the key component in changing the outcome from death to survival when cardiac arrest occurs. It involves providing cardiopulmonary resuscitation (CPR) and utilizing an automated external defibrillator (AED) to help restore the normal cardiac rhythm. By equipping more individuals with BLS training, it will enhance community preparedness and public health. Aim This study aimed to evaluate the general population's awareness, knowledge, and attitude toward BLS in Saudi Arabia. Subject and methods This cross-sectional study was conducted among the Saudi general population covering all five main regions in Saudi Arabia (Central, Eastern, Western, Southern, and Northern). A self-administered questionnaire was sent through volunteer data collectors in every area in which they live to the population using a Google (Google, Inc., Mountain View, CA) survey. The questionnaire includes socio-demographic characteristics (i.e., age, gender, region of residence, etc.) to assess the awareness, knowledge, and attitude toward BLS using a 20-item questionnaire based on the American Heart Association (AHA). Results Of the 992 participants, 615 (62%) were females, and 325 were aged between 26 and 35 years (32.8%). Four hundred eleven participants (41.4%) attended training related to BLS. The most common source of training information was a resuscitation society course (51.8%), followed by the university curriculum (24.6%) and school (10.7%). The overall mean knowledge score was 9.64 (SD 2.92) out of 20 points. Among them, 487 (49.1%) had moderate knowledge levels, 466 (47%) were poor, and only 39 (3.9%) had good knowledge. Factors associated with increased knowledge include younger age, living outside Central Region, better education, being a healthcare worker, knowing how to give a cardiac massage, previous participation in BLS training, and witnessed of sudden death. The biggest barrier that would prevent participants from providing a cardiac massage is fear of making a mistake (63.1%). Conclusion The general population's knowledge of BLS was found to be inadequate. However, younger participants who had a better education and worked in a healthcare institution tended to be more knowledgeable about BLS than the rest of the groups. The gaps in the knowledge are evidently seen in this study. Hence, appropriate measures are needed to bridge knowledge gaps. Healthcare authorities should devise a program to deliver necessary information about the basic facts of BLS throughout the community., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Deanship of Scientific Research of King Faisal University issued approval KFU-REC-2023-SEP-ETHICS1202. Having reviewed the details submitted by the applicant regarding the abovenamed research project, the Research Ethics Committee at King Faisal University grants its ethical approval to the protocol. Projects may be subject to an audit or any other form of monitoring by the committee at any time. The committee may request a regular report on the progress of the project to ensure that researchers are committed to the highest ethical standards. Researchers are held accountable for the storage, retention, and security of original data obtained from projects. Any substantial alterations to the project or emerging events or matters that may affect the ethical acceptability of the project must be reported immediately to the committee via email (ialjreesh@kfu.edu.sa) or phone (0096615899773). Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alghamdi et al.)

Background: Eye diseases such as cataracts and glaucoma significantly contribute to vision impairment and blindness worldwide. While cataracts are the leading cause of preventable blindness, glaucoma, often referred to as the "silent thief of sight", can lead to irreversible vision loss if untreated. Despite their prevalence, awareness and understanding of these conditions remain low, particularly in regions like Saudi Arabia, where demographic changes and rising diabetes rates exacerbate the burden of eye diseases. This study aims to assess the knowledge and perceptions of cataracts and glaucoma among residents of Jazan to identify gaps and inform public health interventions., Methods: A cross-sectional online survey was conducted among participants aged 18 years and older in Jazan. The structured questionnaire assessed demographic information, awareness of cataracts and glaucoma, understanding of symptoms, and perceptions of treatment options. Data collection took place over four weeks, with statistical analysis performed using descriptive statistics to summarize findings., Results: A total of 426 participants completed the survey. Of these, 43.9% (n = 186) were aware of cataracts, while only 28.1% (n = 119) recognized glaucoma. Awareness of cataract symptoms varied, with 43.4% (n = 184) identifying blurred vision; however, 71.5% (n = 303) reported being unaware of glaucoma. A significant majority (68.2%, n = 289) recognized surgical treatment for cataracts, but only 27.8% (n = 118) were aware of treatment options for glaucoma. High levels of uncertainty about both conditions suggest a critical lack of understanding in the community., Conclusion: This study emphasizes the need for improved awareness and understanding of cataracts and glaucoma in Jazan, Saudi Arabia. By implementing targeted public health strategies, healthcare providers can enhance knowledge, encourage regular eye examinations, and ultimately reduce the burden of visual impairment in the community., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Jazan University Ethics Committee issued approval 2024. This study was conducted in accordance with the ethical standards of the Declaration of Helsinki. All participants were informed about the purpose of the study and provided online informed consent before completing the survey. Participation was entirely voluntary, and respondents were assured that their data would remain confidential and anonymous, with no identifying information collected. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alhazmi et al.)

Introduction Dental students are the future of the dental profession, and since digital dentistry is becoming more prevalent, they must receive an education that incorporates digital workflows and practices. This study aimed to determine the level of dental students' knowledge, awareness, and perception (KAP) of digital dentistry, as well as the influence of the type of school funding and information source on these aspects. Methods A cross-sectional online survey was performed between September 2023 and March 2024. Dental students from Egyptian public and private universities constituted our study sample. A 22-item questionnaire with four sections was employed for data collection. The data were analyzed using IBM SPSS Statistics for Windows, Version 25, (Released 2017; IBM Corp., Armonk, NY, USA). Results Out of 390 responses, 213 (54.6%) were females, 218 (55.9%) were students, and 287 (73.6%) received computer-aided design/computer-aided manufacturing (CAD/CAM) training in their dental schools. Most of the participants had a moderate to high level of knowledge (48.50% and 43.60%, respectively); 73.10% showed a moderate level of awareness; and 73.60% had a high level of perception of digital dentistry. Additionally, it was shown that interns and participants who gained their knowledge from social media and attended hands-on workshops had significantly higher KAP scores (p ≤ 0.05). The knowledge and perception scores were also impacted by attending a private dental school (p ≤ 0.05). Furthermore, reading books or articles considerably raised participants' awareness, whereas sharing knowledge with peers greatly enhanced their knowledge (p ≤ 0.05). Conclusion Our study revealed a moderate to high level of knowledge, a moderate level of awareness, and a high level of perception about digital dentistry among the majority of participants. Moreover, it underscores the need for comprehensive digital dentistry educational courses, emphasizing practical hands-on training - especially in public dental schools - to equip future dentists with the necessary knowledge and skills., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Unite of Research Ethics Approval Committee at Pharos University issued approval 04-2022-11-27-3-047. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Hall et al.)

Background Congenital umbilical and inguinal hernias are prevalent in infants and children. The exact incidence of congenital umbilical hernias remains unclear due to their typically asymptomatic nature, resulting in limited medical attention-seeking by parents. As these hernias are associated with serious complications such as incarceration, strangulation, and, rarely, obstruction, timely recognition and early medical intervention play a critical role in preventing these complications. This study aimed to investigate the level of knowledge and awareness of congenital inguinal and umbilical hernia and its complications in the pediatric population among parents in the Qassim region of Saudi Arabia. Methodology This cross-sectional study was conducted among parents living in the Qassim region of Saudi Arabia. A self-administered questionnaire was sent to the targeted parents using an online survey. The questionnaire included sociodemographic data (i.e., gender, marital status, education), general awareness about umbilical and inguinal hernia, and a six-item questionnaire to measure parents' knowledge regarding umbilical and inguinal hernia. Results A total of 440 parents responded to our survey (30.9% males vs. 69.1% females). Overall, 49.5% had at least four or more children. Of the study participants, 19.8% knew of both umbilical and inguinal hernias. The overall median knowledge score of six knowledge items was 2.00 (interquartile range = 2.00). Most parents (64.3%) had poor knowledge, and only 2.3% of them had good knowledge. Higher education, awareness of the meaning of congenital inguinal or umbilical hernias, and having children with a previous history of umbilical or inguinal hernia symptoms were the factors associated with increased knowledge. Conclusions The parents' knowledge regarding congenital umbilical or inguinal hernia was deficient. Parents with self-knowledge of the disease were likely to demonstrate better umbilical and inguinal hernia knowledge than the rest of the groups. This study highlights the importance of awareness campaigns in bridging the knowledge gap., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Qassim Region Research Ethics Committee, Registered at National Committee of Bio-Ethics (NCBE) Registration Number H-04-Q-001 issued approval 60746427. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Assakran et al.)

Background: Insufficient understanding of radiation safety contributes to heightened exposure vulnerability among patients and medical personnel., Objectives: This study assessed radiation safety awareness among non-radiology staff at Tabuk hospitals, Saudi Arabia., Methods: This cross-sectional study included 203 non-radiology staff from the King Salman Armed Forces, King Fahad Specialist, and King Khaled Hospitals in Tabuk City, Saudi Arabia. A self-administered, structured questionnaire was used. Regression analysis was used to detect variables affecting radiation safety awareness., Results: According to Bloom's cut-off categories for knowledge, most non-radiologists at Tabuk hospitals (76%) had low awareness levels. Having a moderate-to-high knowledge level regarding radiation safety was significantly associated with being a physician (p = 0.004), having a longer length of service (p = 0.001), having attended a radiation protection and safety course (p = 0.049), and increased frequency of ordering imaging per day (p < 0.001). Gender had no significant effect on the knowledge level (p = 0.854). Multivariate regression analysis revealed that the daily frequency of ordering images was the only independent significant factor associated with having a moderate-to-high level of knowledge (OR: 6.222, 95% CI: 2.706-14.308, p < 0.001)., Conclusions: Non-radiologists in Tabuk hospitals have low awareness of radiation safety. Strong associations were noticed between awareness level and being a physician, having clinical experience, attending a radiation protection and safety course, and increasing the frequency of ordering imaging daily. Training courses about the hazards of radiation and the safety measures could lower the frequency of daily exposure to radiation., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Kingdom of Saudi Arabia Ministry of Education University of Tabuk Research Ethics Committee issued approval UT-341-193-2024. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Wally et al.)

Background:  Organ transplantation is a critical, life-saving procedure revolutionizing healthcare. Despite medical advancements, there remains a global shortage of organs available for transplantation. This is more pronounced in India where the organ donation rate is significantly low., Objective:  To assess the knowledge and attitude toward organ donation among students and professionals in medical colleges of Patna, Bihar., Methods:  A cross-sectional study was conducted in three government medical colleges located in Patna that included 666 participants comprising faculty, resident doctors, nursing staff, medical and nursing students, and interns. Data were collected using a pre-designed structured questionnaire comprising a socio-demographic profile and knowledge and attitude of participants toward organ donation. The data were analyzed using descriptive statistics and multivariate analysis., Results: The mean age of study participants was 23±4.24 (SD). The majority (504, 75.7%) of participants were aged between 21 and 30 years and the majority (372, 55.9%) were females. There were significant differences in knowledge about organ donation across groups. Faculty and resident doctors demonstrated higher awareness (113, 73.9%) compared to others. Attitude toward organ donation was positive overall, with the majority (614, 92.2%) supporting organ donation campaigns. However, misconceptions about organ donation and its legal aspects persisted among participants., Conclusion:  There is a need for targeted educational intervention to improve knowledge and dispel myths about organ donation among medical students and professionals., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Ethics Committee, All India Institute of Medical Sciences, Patna issued approval RDIAMS/Pat/2023/RAC/95. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Krishna et al.)

Background Colorectal cancer (CRC) poses a significant challenge to healthcare providers. Spreading awareness, providing preventive measures, and implementing screening programs are essential for detecting and halting the progression of the disease and decreasing the mortality associated with this type of malignancy. This study aimed to assess public knowledge and awareness of colorectal cancer preventive measures and screening programs among residents of Riyadh, Saudi Arabia, and also to design better healthcare interventions or policy development. Methods This cross-sectional study was carried out among residents in Riyadh, Saudi Arabia. A self-administered questionnaire was sent to participants using a Google survey. The questionnaire consisted of socio-demographic characteristics (age, gender, marital status, and occupation), a general understanding of CRC and its prevention, risk factors for developing CRC, barriers to undergoing CRC screening, and a 21-item questionnaire to assess awareness of CRC preventive measures. Results Of the 420 respondents, 301 (71.7%) were female, and 134 (31.9%) were between 18 and 29 years old. The overall mean awareness score was 12.5 (SD 3.05) out of 21 points. Accordingly, 240 (57.1%) were categorized as having moderate awareness, 70 (16.7%) as good, and 110 (26.2%) had poor awareness levels. Being younger, being unmarried, having heard of CRC and screening tests that detect colon cancer, and being aware of the CRC early detection campaign in Saudi Arabia were the factors associated with increased awareness. Conclusion There was modest awareness of CRC preventive measures among residents living in Riyadh. Significant predictors of increased awareness include younger age, being unmarried, having heard of CRC, having heard of screening tests to detect CRC, and awareness of the CRC early-detection campaigns in Saudi Arabia. Healthcare providers have a vital role in increasing awareness of CRC's preventive measures., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Imam Mohammad Ibn Saud Islamic University IRB (IRB number HAPO-01-R-0011) issued approval 504-2023. The IMSIU research ethics committee approved the study protocol (project number 504-2023, approval date, July 1, 2023). Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Azzi et al.)

Background Pharmacovigilance is defined as the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or other drug-related problems. Underreporting of adverse drug reactions (ADRs) is a global issue, and adequate knowledge among healthcare professionals is essential. Engaging young doctors and nursing professionals in pharmacovigilance is crucial for promoting ADR reporting. Objectives The objective of this study is to evaluate the knowledge and awareness of ADRs and pharmacovigilance among medical and nursing students and staff in a tertiary care hospital in Vijayapura, India. Methods A cross-sectional, observational, questionnaire-based study was carried out using a validated questionnaire that included a total of 19 questions related to knowledge and awareness aspects. This was distributed electronically using Google Forms. By using the convenience sampling method, a sample size of 96 participants was calculated for each group (medical and nursing), and this was rounded to 100 participants per group to account for potential dropouts and to ensure the strength of this study. All the questions were peer-reviewed by expert faculties from the Department of Pharmacology. Results The data analysis showed that medical students and staff had superior knowledge of ADRs and pharmacovigilance. Nursing students and staff exhibited greater awareness of the nearest pharmacovigilance center and ADR monitoring centers in India. Nursing students and staff were more active in ADR and pharmacovigilance awareness programs. Conclusions This study clearly shows the importance of flexible attitudes and robust education in pharmacovigilance and ADR reporting among healthcare professionals. Executing simulation-based training can strengthen the skills and confidence of both medical and nursing professionals in ADR reporting and pharmacovigilance., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Bijapur Lingayat District Educational University (BLDE Deemed to be University) Shri B M Patil Medical College Hospital and Research Centre Ethics Committee issued approval BLDE (DU)/IEC/ 1103/2024-25. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Raikar et al.)

Background Interventional radiology (IR) utilizes minimally invasive procedures guided by imaging to diagnose and treat various conditions, offering less invasive alternatives to traditional surgery. Despite its importance, awareness among family medicine practitioners can vary, affecting patient care. While IR has advanced in Saudi Arabia, there are limited data on family medicine practitioners' understanding of IR. This study assesses awareness of IR procedures among family medicine doctors in Jazan and their perceived need for further education. Methods A cross-sectional interview-administered survey was conducted online among family medicine doctors in Jazan via social media. The survey assessed demographic data, awareness of IR procedures, self-rated knowledge, and attitudes towards IR. Participants' understanding of IR training, hospital privileges, outpatient clinics, and recognition by the Saudi Commission for Health Specialties (SCHS) was evaluated. Data were analyzed using descriptive statistics and chi-square tests. Results Out of 395 respondents, the age distribution was as follows: 20-29 years (44.3%), 30-39 years (32.9%), and 40 years or older (22.8%). Gender distribution was as follows: females (44.6%) and males (55.4%). Specialties included family medicine consultants (10.6%), residents (32.4%), specialists (22.8%), and general practitioners (34.2%). Awareness of IR procedures varied: uterine fibroid embolization (58.7%), coronary angiography (57.5%), vascular angioplasty (63.5%), radiofrequency ablation (61.3%), peripheral vascular bypass (61.8%), brain biopsy (56.2%), nephrostomy tube placement (59.5%), varicose veins treatment (63.0%), and cystoscopic tumor resection (54.7%). Self-rated knowledge was as follows: poor (46.8%), adequate (27.1%), good (15.7%), and excellent (10.4%). Most believed that interventional radiologists' training was in radiology (62.8%), with fewer attributing it to vascular surgery (20.5%) or a combination (16.7%). Regarding privileges and facilities, 248 (62.8%) reported hospital admitting privileges for IRs, 251 (63.5%) reported outpatient clinics, and 45 (11.4%) were unsure about admitting privileges. SCHS recognition was confirmed by 267 (67.6%). Referrals to IRs were made by 283 (71.6%), and 260 (65.8%) would increase referrals with more knowledge. The perceived benefit of additional education was as follows: no benefit (48.4%), some benefit (30.6%), and significant benefit (21.0%). Conclusion The study reveals gaps in awareness and knowledge of IR among family medicine doctors in Jazan. While there is recognition of IR's value and a willingness to refer patients, variations in knowledge highlight the need for targeted educational interventions. Improving education on IR could enhance integration into patient care and optimize outcomes., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Jazan Health Cluster Ethics Committee issued approval 2423. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Hendi et al.)

Background Diabetes mellitus is a significant global health problem characterized by high blood sugar levels due to either a lack of insulin or insensitivity to it. Concerns about diabetes complications are growing both globally and locally, making effective preventive measures crucial to tackle these complications. This research aimed to determine the level of knowledge and awareness regarding type 2 diabetes complications among patients in Homs, Syria, during the ongoing conflict. Methods A cross-sectional study was conducted among 1016 diabetic patients aged 16 years and above attending internal medicine and diabetes clinics in Homs City through a structured questionnaire administered via social media, telephone interviews, and paper forms. The data collected were analyzed using SPSS version 23.0 (IBM Corp., Armonk, USA). Descriptive statistics were used to summarize the demographic characteristics. In contrast, inferential statistics such as the chi-square test were used to test for associations between different variables with p-value < 0.05 as the significance level. Results The study found that 478 (47.1%) of participants were male, and 538 (53%) were female. The majority 652 (64.2%) were between 46 and 70 years old, and 422 (41.5%) had primary-level education. Most were married 750 (73.8%) and lived in urban areas 856 (84.2%). Diabetes knowledge varied significantly by age, education, occupation, and residence. Housewives and those with lower education levels had the least knowledge, while urban residents and those with 1-5 years since diagnosis had better awareness. Individuals with relatives in the medical field had higher knowledge levels. Results indicate that gender did not significantly influence diabetes knowledge (p = 0.19), while younger adults showed poorer awareness compared to older age groups (p < 0.05). Higher education levels were associated with better knowledge (p < 0.05), and a family history of diabetes correlated with greater awareness of complications. Occupation significantly impacted knowledge, with employed individuals and urban residents demonstrating higher awareness levels (p < 0.05). Diabetes knowledge peaked during the 6-10 year disease duration (p < 0.05). Conclusion This study assesses diabetes knowledge and management practices among 1016 participants in Homs, Syria, focusing on demographic and socioeconomic factors. Our findings underscore the need for targeted educational initiatives to improve diabetes management, particularly among younger, less educated, and rural populations in Homs. The analysis reveals significant knowledge gaps about diabetes across different demographics in Homs, highlighting the need for targeted educational programs, especially for younger individuals, the less educated, and rural residents. The study emphasizes the importance of education and medical practice in understanding diabetes, particularly in conflict-affected areas., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Review Board of Al-Baath University Hospital issued approval 103550. This study was approved by the institutional review board (IRB) of Al-Baath University Hospital. Participants provided their written informed consent, and anonymity and confidentiality were secured by providing each participant with a unique identification number that was only visible to the research team. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Albawab et al.)

Background: Congenital scoliosis (CS) is a developmental spinal deformity characterized by an abnormal curvature of the spine, affecting one in 1,000 births. The mainstay of treatment involves either observation or surgery in significant curve progression. The optimal timing of surgical intervention is debated, with early intervention preferred. Therefore, understanding physicians' and patients' families' perspectives is crucial for optimizing surgical outcomes in CS., Objective: To assess the awareness and knowledge of physicians and patients' families regarding current, as well as new surgical practices and the optimal timing of treatment for CS., Methods: A cross-sectional study was conducted in Saudi Arabia using an online self-administered questionnaire distributed through social media platforms and neurosurgery clinics. Levels of awareness were assessed by a knowledge-scoring system., Results: The study involved 403 participants, primarily patients' families (85.1%, N = 343) and physicians (14.9%, N = 60). The results show that physicians had a significantly higher correct response than patients' families regarding the ideal age for surgical correction of CS, the timing of surgical intervention whether before or after maturity, and the role of conservative management, as evident from statistically significant p-values of <0.001, 0.031, and <0.001, respectively. On the contrary, patients' families excelled in understanding interventions irrespective of symptomatic status if Cobb's angle is 40 degrees or above, with a statistically significant p-value of 0.031. Both groups exhibited a good level of overall knowledge, as evidenced by mean awareness scores of 12.18 and 11.64, respectively. Additionally, physicians had a statistically significant higher level of awareness compared to patients' families, with a p-value of (0.014). However, both groups demonstrated poor knowledge of the latest techniques, including distraction-based magnetically controlled growing rods (MCGRs), growth-guided modern Luque trolleys, and posterior dynamic deformity correction (ApiFix)., Conclusion: The mean awareness score of both physicians and patients' families indicates a good level of knowledge. However, both groups exhibited poor knowledge in relation to the optimal timing of treatment and new surgical techniques., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Review Board at Imam Abdulrahman Bin Faisal University, Saudi Arabia issued approval (IRB#: IRB-UGS-2023-01-429). The application was reviewed and approved at lmam Abdulrahman Bin Faisal University IRB through an Expedited Review on Sunday, October 29, 2023. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alshammasi et al.)

Background Total knee arthroplasty (TKA) is a successful surgical intervention for advanced knee arthritis. The efficacy of TKA in reducing pain and restoring joint function has been well documented. Despite the rewarding outcomes of TKA for knee osteoarthritis patients, their willingness to consider the procedure is limited. Aim This study aimed to assess patients' awareness and knowledge of total knee arthroplasty benefits and complications. Further, the reasons and factors contributing to reluctance among orthopedic patients in Saudi Arabia should be determined. Methods An online, structured, and self-administered questionnaire was used to collect data from adult orthopedic patients of both genders who were reluctant to undergo total knee arthroplasty despite surgeons' recommendations. The online questionnaire link was shared across multiple platforms, orthopedic forums, and healthcare social media channels. Qualitative data were presented as frequencies and percentages, while continuous data were reported as the mean (standard deviation [SD]). The statistical package for the social sciences software program was used for statistical analysis. Results A total of 629 participants were involved. The awareness of the expected benefits score, on a scale from 7 to 35, showed a mean (SD) of 20.9 (5.6). The score of the attitude towards expected complications, on a scale from 5 to 25, had a mean (SD) of 15.2 (3.6). The attitude towards the expected complications showed a significantly higher mean (SD) score in the older group aged >60 years than the younger one aged <40 years (15.7 (4.1) vs. 14.9 (3.5), respectively). Likewise, overweight and obese participants showed a significantly higher mean (SD) expected complications score compared to the healthy and underweight ones (15.4 (3.7) vs. 14.8 (3.5), respectively). The recorded reasons for refusal to undergo TKA were fear of anesthesia complications (317, 50.4%), followed by financial limitations (245, 39.0%), the unavailability of experienced surgeons (232, 36.9%), and fear of unfavorable outcomes (189, 30.0%). Conclusion There was a gap in knowledge and awareness of total knee arthroplasty among orthopedic patients in Saudi Arabia. Perceptions of benefits were inadequate, and there were misconceptions about the expected complications. The level of expected complications was higher among elderly and obese patients. Furthermore, fear of anesthesia complications and unfavorable outcomes, in addition to economic and financial problems, constituted major barriers to undergoing the procedure., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Ethics Committee of The University of Tabuk issued approval UT-384-227-2024. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alkindy et al.)

Background Adverse drug reactions (ADRs) represent a significant public health concern, contributing to mortality, morbidity, and healthcare costs worldwide. Healthcare practitioners especially doctors play a vital role in identifying and reporting ADR. This study investigates the prevalence of knowledge regarding ADR among doctors and enhances it with educational intervention. It also explores the association between demographic factors and baseline ADR awareness. Methods A prospective cross-sectional interventional study was conducted among doctors in Ahmedabad, India, to evaluate their knowledge of ADR reporting and the effectiveness of an educational video intervention. Pre- and post-intervention questionnaires were administered to assess knowledge improvement. Statistical analysis, including paired t-tests and chi-square tests, was performed to evaluate the intervention's impact and explore associations between demographic factors and ADR awareness. Results Analysis of pre- and post-intervention questionnaires revealed a significant increase in correct response rates post-intervention, indicating the effectiveness of the educational video intervention. Demographic factors, particularly age, were associated with ADR awareness. Following the intervention, participants demonstrated an improved understanding of ADR definitions, WHO causality assessment, reporting mechanisms, and challenges faced by pharmacovigilance programs. All participants found the video helpful and expressed intent to share their knowledge post-intervention. Conclusion The results of the study suggest that educational video intervention can serve as an effective tool for understanding ADR concepts and pharmacovigilance practices. Moreover, the association of demographic factors, particularly age, with ADR awareness further emphasizes the importance of educational interventions in addressing specific population needs., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. NHL Institutional Review Board (NHLIRB) issued approval NHL/IRB/2023/APRIL/10 No. 8. During the meeting, the members of the NHLIRB reviewed the submitted documents and discussed the study in detail. The investigators were able to answer the queries raised by the committee satisfactorily. The committee decided to collectively approve the conduct of the above study as presented. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Patel et al.)

Background Anaphylaxis is a severe hypersensitivity reaction caused by IgE-mediated mechanisms. This life-threatening condition affects multiple body systems. Global lifetime prevalence estimates for anaphylaxis range from 0.3% to 5.1%, with increasing incidence noted, particularly among young individuals. Symptoms range from mild skin manifestations like urticaria and pruritus to severe respiratory distress and hypotension. Objectives This study aimed to assess the knowledge level of medical interns in the Medina region, Saudi Arabia, regarding the diagnosis and management of anaphylaxis. Method A prospective cross-sectional study was conducted in hospitals in Saudi Arabia by delivering a questionnaire designed to assess the level of awareness and knowledge (including signs, symptoms, and management of anaphylaxis) among medical interns in the Medina region. The data collected were coded and analyzed using IBM SPSS Statistics for Windows, Version 22.0 (released 2013, IBM Corp., Armonk, NY). Results The study involved 291 interns from the universities in the Medina region. Most participants (275, 94.5%) correctly defined anaphylaxis and identified food allergies or insect stings as the main triggers (254, 87.3%). The participants demonstrated good knowledge of health education practices and anaphylaxis symptoms, such as the importance of carrying an adrenaline auto-injector (269, 92.4%) and recognizing syncope as a cardiovascular symptom (196, 67.4%). Regarding management, most correctly identified the initial step as removing the allergen (226, 77.7%) and epinephrine as the preferred medication (256, 88.0%). Significant gender differences were observed in the knowledge of management aspects (P = 0.001, P = 0.002, P = 0.049, P = 0.004, P = 0.001). Conclusion The study found that most participants had a good understanding of the definition of anaphylaxis and its most common triggers. The participants also demonstrated knowledge of symptoms and signs associated with anaphylaxis and the appropriate management of anaphylaxis. However, there were some differences in knowledge between females and males, suggesting that further education and awareness campaigns may be needed to ensure an accurate and consistent understanding of anaphylaxis among both genders. Overall, the study highlights the importance of education and awareness in effectively managing anaphylaxis and preventing its complications., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Taibah University, College of Medicine Research Ethics Committee (CM - REC) issued approval STU-22-20. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Algrigri et al.)

Aim: This study aims to evaluate the awareness and knowledge of ionizing radiation in common radiological investigations, as well as the associated risks, among medical and applied medical sciences students at Majmaah University in Majmaah, Saudi Arabia., Materials and Methods: This cross-sectional study involved 209 participants who completed an anonymous electronic questionnaire consisting of 21 questions. Participants were categorized based on demographic characteristics and assessed for their awareness and knowledge of radiation and its associated risks. Data analysis was conducted using the Statistical Package for the Social Sciences (SPSS) software, version 24.0 (IBM Corp., Armonk, NY, USA). Qualitative data comparisons were performed using the Chi-square test, with a p-value of <0.05 considered statistically significant., Results: A total of 209 participants completed the questionnaire, with a nearly equal distribution of males (49.8%) and females (50.2%). Most of the participants were medical students (59.3%). The overall knowledge score had a mean of 2 (SD=2) and a range of 0-7. The overall awareness score had a mean of 3 (SD=2) and a range of 0-6. Male gender and knowledge had a significant association (p=0.022). Applied medical sciences students had a significantly higher awareness level than medical students (p=0.004). There was a significant association between academic level and knowledge level (p=0.025), which was highest among third-year students., Conclusion:  Overall medical and applied medical sciences students' knowledge and awareness of ionizing radiation dose and the health risks associated with it was reported to be low. The results highlight the need to train medical and applied medical sciences students with sufficient radiological education that enable them to adhere to safe practices in the future., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. The Majmaah University for Research Ethics Committee (MUREC) (H-01-R-088) issued approval MUREC-Mar.25/COM-2024/11-8. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alali et al.)

Background The common chronic condition known as irritable bowel syndrome (IBS) lacks any visible anatomical, biochemical, or pathogenic cause. IBS significantly strains healthcare systems by sending a considerable number of patients to gastrointestinal clinics. Objective The present study investigated the knowledge, awareness, and prevalence of IBS among a sample of the Saudi community. Methods The current cross-sectional investigation was carried out from January 2, 2024, to March 15, 2024, using an electronically distributed questionnaire. IBM SPSS Statistics for Windows, Version 26 (Released 2019; IBM Corp., Armonk, New York, United States) was employed for statistical analysis. Results The study included 1,008 participants (655, 65% females and 353, 35% males). Most individuals (421, 42%) were from the age group of 18-30 years. Among participants, the prevalence of IBS was 31.8% (n=320). Regarding IBS knowledge, 42.2% (n=425) had low knowledge scores, 38.6% (n=389) had moderate knowledge scores, and only 19.2% (n=194) had high knowledge scores. The majority of respondents (886, 87.9%) believe that IBS affects QoL. Most participants (885, 87.8%) had good knowledge of the common symptoms of IBS. Additionally, 85.1% (n=858) of respondents recognized the psychological and emotional effects associated with IBS. Younger participants (under 20 years old) and single participants had significantly lower knowledge scores than their comparable groups (p<.001). Female participants had a higher percentage of high knowledge scores (13.4%) than males (5.9%) (p=.002). Conclusion The current study's findings showed that participants' knowledge of IBS was inadequate. Around one-third of the participants suffered from IBS. Younger, unmarried individuals and females had different knowledge scores than their counterparts. The study's findings imply that further education and awareness campaigns are needed to improve understanding of IBS., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Research Ethics Committee of King Abdulaziz University, Jeddah issued approval 718-23. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Baig et al.)

Introduction: Most dental students are interested in pursuing a postgraduate degree after completing their Bachelor of Dental Surgery (BDS). Among the various specialties, oral surgery, which bridges the fields of medicine and dentistry, is the most attractive option for many young dental professionals. This study aimed to explore the factors influencing students' choices for postgraduation in oral and maxillofacial surgery (OMFS) and to assess their knowledge, attitudes, and perceptions (KAP) towards this branch of dentistry., Materials and Methods: An online survey was conducted with 450 third- and final-year BDS students and interns from various dental colleges. The survey included a self-administered questionnaire designed to collect demographic information and insights into students' motivations and KAP regarding postgraduation in OMFS. The questionnaire was distributed via an internet-based survey program and shared through WhatsApp Messenger accompanied by a consent form. To determine the significance between variables, non-parametric test, such as the chi-square test, was employed. The KAP scores were calculated and represented as mean ± standard deviation (SD), and intergroup comparisons were performed using the two-way independent T-test (for two groups) and two-way analysis of variance (ANOVA) test (for three groups). The level of significance was set at P ≤0.05., Results: The sample comprised 320 (71%) females and 130 (29%) males. A total of 285 (63.33%) respondents wanted to pursue postgraduation after BDS, whereas 130 (28.89%) did not. Long working hours, risk and liability, and lack of skills were the main reasons for not opting for postgraduation in OMFS as a career option. The primary reasons cited for choosing OMFS included better career prospects (75.08%%) and the influence of the mentor (59.65%). The main benefits of choosing postgraduation in OMFS were advanced skills (88.77%), and high earning (85.61%). The mean KAP scores were higher for government institutions in urban areas and for males., Conclusion: This study revealed that a substantial number of undergraduate dental students were inclined to specialize in OMFS after graduation. The combination of medicine and dentistry significantly influences the choice of OMFS as a career option., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Ethical Committee of Guru Nanak Dev Dental College Sunam issued approval GNDDC/IERB/04/2024/08. This survey was conducted in accordance with the ethical principles outlined in the Declaration of Helsinki. The first section of the questionnaire's informed consent form was structured, including the study objectives, target population, principle of voluntariness, and other essential elements. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Kumar et al.)

Background: Noise-induced hearing loss (NIHL) is a prevalent and preventable health issue globally. This study aims to evaluate the symptoms, knowledge, beliefs, and preventive practices regarding NIHL among the general population of the southern region of Saudi Arabia., Materials & Methods: A cross-sectional study was conducted from May to July 2024, using a self-administered, validated electronic questionnaire distributed in Arabic via social media platforms. The questionnaire assessed socio-demographic data, NIHL awareness, attitudes toward prevention, and personal practices regarding noise exposure. The sample included 400 participants analyzed using SPSS version 23 (IBM Corp., Armonk, NY), with associations measured through the chi-square and Fisher's exact tests., Results: Most participants were Saudi nationals (97%) and females (81.3%). Symptoms of NIHL, such as tinnitus and the need to increase TV or radio volume, were prevalent among participants. Most participants (88.5%) were aware that high sound levels affect hearing, yet only 9.5% correctly identified the minimum duration of exposure that could harm hearing. Social media was the primary source of information (51.3%). Positive preventive practices were noted, with 66% lowering device volumes and 55.3% recommending sound restrictions on tablets. Significant associations were found between better preventive practices and higher income as well as marital status., Conclusion: The study highlights the high basic awareness of NIHL but identifies critical knowledge gaps regarding the minimum sound level and duration that affect hearing negatively. Enhanced public health education and technological interventions are needed to improve prevention practices. Future research should include longitudinal studies and diverse populations to better understand and address NIHL., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Research Board of Al Baha University issued approval REC/SUR/BU-FM/2024/70. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alzahrani et al.)

Background: The Health Sector Transformation Program (HSTP) has been established as part of Saudi Vision 2030. Despite the significant progress achieved in previous years, the HSTP addresses multiple challenges. One of these challenges is that the current healthcare model prioritizes treatment over prevention. Therefore, prioritizing preventive healthcare measures is crucial., Objectives: This study aims to assess the levels of awareness and knowledge among the public health and preventive medicine physicians in Saudi Arabia towards the national healthcare transformation program., Method: In this cross-sectional study, we surveyed public health and preventive medicine physicians in Saudi Arabia. We collected data through a newly developed and validated self-administered questionnaire, which was distributed online. The survey questionnaire consisted of three sections: participants' background characteristics; measurement of public health and preventive medicine physicians' awareness of the HSTP and their confidence in their awareness; and measurement of the physicians' knowledge of the HSTP through six multiple-choice questions., Results: In this study, 307 public health and preventive medicine physicians in Saudi Arabia participated. The mean age ± SD was 33.1 ± 5.1 years, with 54.7% being public health and preventive medicine residents, 33.2% specialists, and 12.1% consultants. Most participants showed high awareness of the HSTP and its strategic objectives. Over two-thirds correctly defined HSTP, value-based healthcare, and the new Model of Care (MOC), while about 50% demonstrated inadequate knowledge regarding Accountable Care Organizations (ACOs) and the "Keep Well" system. Older physicians, consultants, and those with more years of work experience had higher knowledge scores. Regression analysis revealed that job rank significantly influenced public health and preventive medicine physicians' knowledge of the HSTP., Conclusion: This study shows that while public health and preventive medicine physicians are generally aware of HSTP's objectives, they have inadequate confidence in their knowledge, highlighting the need for better information dissemination. Awareness of the MOC is high, but gaps persist in understanding specific components like the "Keep Well" initiatives. The study also found that job rank and experience influence knowledge levels, suggesting the need for broader dissemination of the HSTP concepts., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. The institutional review board (IRB) of King Fahad Medical CityKing Fahad Medical City issued approval (24-099C). Participants provided informed consent prior to their inclusion in the study, and their confidentiality was maintained. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Aldawsari et al.)

Background Assessing DVT prevention awareness in the Al Qunfudhah region involves measuring public knowledge about risk factors, prevention, and early treatment through surveys. DVT, characterized by blood clots in the deep veins, poses serious risks, including pulmonary embolism. Raising awareness is crucial for high-risk groups, such as those with prolonged immobility or certain medical conditions, underscoring the need for targeted education and prevention strategies. Objectives The objective of the study is to determine the level of awareness regarding deep vein thrombosis (DVT) prevention measures among the general population of Al Qunfudhah governorate. Methods This cross-sectional study was conducted in Al Qunfudhah, Saudi Arabia, from January 2024 to April 2024. Data were collected using an online questionnaire targeting individuals aged 18-65 in the region. Analysis was performed using RStudio software version 4.3.1. Results Most participants (69.0%) lacked familiarity with DVT. Their knowledge of risk factors, symptoms, prevention strategies, and complications was limited, with a median knowledge score of 8 out of 21 (IQR: 5-11). Familiarity with DVT was an independent predictor of higher knowledge (β = 4.29, 95% CI 3.58-5.00, p < 0.001). Conclusions Awareness and knowledge regarding DVT prevention among residents of Al Qunfudhah were found to be inadequate. Targeted educational interventions are needed to improve understanding of DVT and its prevention, especially among those unfamiliar with the condition., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Umm Al-Qura University issued approval HAPO-02-K-012-2024-04-2118. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Taha et al.)

Objective:  Even though COVID-19 is no longer in an acute pandemic phase, sustaining awareness and promoting the uptake of COVID-19 vaccines are crucial for preventing future outbreaks and protecting public health. This study explores the awareness and uptake of COVID-19 vaccines among residents of Bisha, Asir province. It examines sources of information, healthcare providers' influence, and community engagement initiatives. The findings can inform future public health policies and strategies, supporting efforts to control the spread of the pandemic and enhance community resilience., Methods:  The cross-sectional study was administered to the adult population in Bisha. The study involved a total of 220 respondents. Data were collected using a questionnaire and analyzed using SPSS version 27 to obtain essential insights., Results: Most respondents (n = 204, 92.73%) reported receiving information about COVID-19 vaccines from healthcare professionals, other people, and family members. The study also revealed that only 46 (20.9%) individuals had exposure to COVID-19, with 36 (78.26%) reporting infection before vaccination and only 10 (21.74%) reporting infection after vaccination. Regarding COVID-19 vaccine first-dose uptake, less than half (27.73%) of the respondents had received the first dose. Among those who took the first dose, 29 (47.54%) took the second dose, while 32 (52.46%) did not. It also shows a statistically significant difference in COVID-19 vaccine uptake based on the participant's age, gender, education level, comorbidity, smoking status, and place of residence (P < 0.05)., Conclusion: There was a significantly high level of awareness about the vaccine, with significant proportions of respondents indicating their willingness to take preventive measures even after vaccination. However, vaccine uptake remains below optimal levels, with various reasons cited for non-vaccination, including concerns about vaccine availability, efficacy, and side effects. Healthcare professionals should intensify public education efforts and ensure the availability of vaccines in various forms at hospitals to address this issue., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Bisha University Ethics Committee issued approval BU/1814/223 (dated 22/03/2021). Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alghamdi et al.)

Purpose: Inguinal hernias lead to several potentially fatal complications such as strangulation. Assessing the prevalence, risk factors, and beliefs of a population is essential to develop appropriate preventive strategies. This study investigated the prevalence, risk factors, and awareness of inguinal hernia in the adult population of Saudi Arabia., Methods: This cross-sectional study enrolled 461 adults aged between 18 and 60 years after excluding those aged <18 and >60 years. This study was conducted in five regions of Saudi Arabia (north, west, central, south, and east). A pre-tested questionnaire was used to collect data on the prevalence, perception, and awareness of the participants. Multivariate regression analysis was used to identify risk factors for inguinal hernia., Results: The study revealed that most participants were men n=262 (56.8%), aged between 18 and 25 years n=241 (52.3%), were single n=278 (60.3%), had a bachelor's degree n=225 (48.8%) and earned less than 50,000 Saudi Riyals annually n=285 (61.8%). Most participants resided in urban areas n=366 (79.4%) with their parents n=230 (49.9%). The prevalence of inguinal hernias in adults was low (5.2%). Our results indicated a significant association between family history of inguinal hernia, chronic cough, bronchial asthma, smoking, and inguinal hernia (p < 0.001). Young adults and undergraduates displayed significantly low awareness of inguinal hernias (p < 0.001)., Conclusion: Family history of inguinal hernia, chronic cough, bronchial asthma, and smoking were factors associated with inguinal hernia. Low awareness levels were observed among young undergraduates, with a moderate overall level of awareness., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Majmaah University Research Ethics Committee (MUREC) (HA-01-R-088) issued approval MUREC-MAY.30/COM-2023/20-5. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Almunifi et al.)

Introduction and objectives The spread of coronavirus disease 2019 (COVID-19) has been a worldwide phenomenon. This study conducted a chronological survey of crisis awareness regarding COVID-19 within different age groups. Methods An internet-based survey was performed on healthy Japanese adults to investigate the value of a hypothetical prophylactic vaccine and therapeutic drug for COVID-19 in each age group. In total, 12 groups comprising males and females in six different age groups, leading to a total of 1,200 individuals, were surveyed on a weekly basis. The survey was conducted on Friday of each week commencing from February 14, 2020, to April 10, 2020. At certain times or events such as when the government released major announcements or when there was a rapid increase in the number of infected individuals, a similar survey was conducted on an additional 1,200 individuals per week. Results A total of 12 surveys, including weekly surveys spanning over nine weeks, were conducted; a total of 19,113 samples from 12,254 individuals were obtained. The mean price for a hypothetical prophylactic vaccine was 2876.3 JPY (26.9 USD) at the first survey and was significantly increased to 3357.4 JPY (31.4 USD) for the most recent survey (p<0.0001). The percentage of healthy individuals who were unwilling to pay for a hypothetical therapeutic drug at the onset of COVID-19 symptoms was higher in the young age group than in the elderly groups at all phases, indicating a low level of crisis awareness among some young individuals. On the other hand, the percentage of those willing to pay for more than the standard prophylaxis influenza vaccine remained almost the same in all age groups, and it also increased when COVID-19 infection was widespread. In the sub-analysis, females who have children and married individuals tended to answer higher costs for prevention. Conclusions Changes in crisis awareness in all age groups were found to be associated with an increasing familiarity along with an increase in the number of locally infected individuals. Though the percentage of those who will not pay was higher in the young age group than in the elderly age group, the percentage of those who will pay more than the standard costs of influenza vaccine or treatment drugs was the same between each aging group., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Review Board of Yokohama City University Medical Center issued approval #B200300041. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Kawahara et al.)

Introduction Amblyopia is a neurodevelopmental disorder of the visual cortex that usually occurs due to abnormal visual development early in life. The clinical importance of amblyopia is that it is a significant cause of visual loss in the pediatric population. Knowing and understanding amblyopia plays a crucial role in management since the earlier the intervention, the better the results. Aim This study aimed to assess the knowledge and awareness of amblyopia among the general population in Saudi Arabia. Subject and methods This cross-sectional study was conducted among the general population in Riyadh, Saudi Arabia. A self-administered Arabic questionnaire was distributed to the general population through social media using Google Forms. The questionnaire includes sociodemographic characteristics (e.g., age, gender, marital status, etc.) and questions to assess the knowledge about amblyopia, including its definition, etiologies, and treatment. Results Of the 488 participants, 57.4% were females, and 38.3% were aged between 26 and 39 years old. Of the participants, 46.5% have heard of amblyopia. The overall mean knowledge score was 16.9 (SD 3.09) out of 32 points. In terms of knowledge, 64.5% had moderate knowledge, 1.8% had good knowledge, and 33.6% had poor knowledge levels. Factors associated with increased knowledge were being older, female gender, married, having children, having a family history of eye disease, and hearing of amblyopia. Conclusion Consistent with the literature, this study finds a need for more knowledge about amblyopia among the general population. Significant predictors of increased knowledge include younger age group, female gender, having children, family history of eye disease, and ever heard of amblyopia., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. King Abdullah International Medical Research Center (KAIMRC) issued approval IRB/0752/23. Dear DR. MOHAMMED TAHA Assistant Professor Ophthalmology, College of Medicine, KSAU-HS Ministry of National Guard Health Affairs Sub-investigators: Nawaf Khaled Alawad, Abdullah Mohammed Alhejji, Faisal Abdullah Alshahrani, Fahad Abdulaziz Aldihan, Faisal Abdulaziz Aldlhan, Nawaf Mohammad Alamer After reviewing your submitted research proposal/protocol and related documents, the IRB has APPROVED the submission. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Aldihan et al.)

Objectives: Teledentistry has emerged as a crucial tool to address oral health needs amidst social distancing measures and lockdowns. Teledentistry during COVID-19 underscores its potential as an adaptive solution, transforming the delivery of dental care and providing a platform for maintaining oral health while prioritizing public safety. The purpose of this study is to investigate the views of Chennai dental professionals on teledentistry, which may serve as a foundation for advancements in patient care and virtual dentistry in the future, and to evaluate awareness, usefulness, and data security regarding telemedicine among Chennai dental professionals using a pretested questionnaire., Methods: By distributing a pretested web-based questionnaire to licensed dental professionals in Chennai, a descriptive cross-sectional study was conducted. The results were statistically analyzed and evaluated., Results: A total of 90 dentists in Chennai responded to the questionnaire, out of which 65 (72.2%) were aware of teledentistry and 32 (35.6%) practiced teledentistry. Around 25 to 29 (30%-37%) dentists were very much concerned about obtaining patients' consent, digital forgery, confidentiality, and hardware reliability in teledentistry., Conclusion: This is the first kind of study ever done among dentists in Chennai, which shows enormous work is required to create awareness and knowledge among dental professionals. To inform dentists and the general public about teledentistry, targeted advertisements pertaining to the same are required., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Sri Ramaswamy Memorial (SRM) Institutional Ethics Committee (IEC) of SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology (SRMIST) issued approval SRMIEC-ST0323-743. This web-based descriptive cross-sectional study got ethical approval from the IEC of SRM Medical College Hospital and Research Centre (SRMIEC-ST0323-743). Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, B et al.)

Background The anterior cruciate ligament (ACL) is a crucial connective tissue that links the femur to the tibia, playing a vital role in stabilizing the knee by resisting forward and rotational movements. ACL tears can occur due to both contact and non-contact sports injuries. Diagnosis and assessment typically involve the Lachman test and magnetic resonance imaging. Initial treatment focuses on reducing swelling, followed by physical therapy or surgery to restore long-term knee functionality. Objective This study aimed to assess the injury prevalence and awareness of ACL and the engagement of preventing training programs among Bahraini athletes across diverse sports. Methods A cross-sectional survey was utilized to evaluate injury prevalence and awareness of ACL and engagement in preventing training among 161 Bahraini athletes from different sports. Data were collected through a detailed questionnaire addressing demographics, sports involvement, ACL injury history, and preventive training. The analysis involved descriptive statistics, one-way ANOVA, and independent t-tests to compare knowledge across sports types. A chi-square test was performed to examine correlations between injury history and training. Results The results showed that athletes in full-contact sports exhibited significantly higher ACL injury awareness compared to those in semi-contact and non-contact sports. Furthermore, a higher percentage of athletes in semi-contact and non-contact sports reported a history of ACL injuries when compared to those in full-contact sports. However, there was no significant difference in the engagement of preventive exercise training across different sports categories. Conclusion A notable gap in ACL injury awareness exists among Bahraini athletes, varying significantly across sport types. The data highlight the need for customized educational programs catering to different sports., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Research and Ethics Committee of the College of Medicine and Medical Sciences at Arabian Gulf University issued approval E13-PI-11-22. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alsaeed et al.)

Background:  Telemedicine is a paradigm shift that utilizes technology for remote healthcare delivery, improving the quality of care., Objectives: This study aims to assess the general population's awareness and perception regarding telemedicine in the central, northern, and western regions of Saudi Arabia., Methods:  A web-based cross-sectional study was conducted in the central, northern, and western regions of Saudi Arabia from January 2024 to May 2024. A structured questionnaire was used to collect data, including sociodemographic information and questions to assess participants' awareness and perception of telemedicine. Data were analyzed using IBM SPSS Statistics for Windows, Version 27 (Released 2020; IBM Corp., Armonk, New York, United States), with significance at p < 0.05., Results:  Out of 414 adult participants in the study, 264 (63.8%) were female, and 205 (49.5%) were below the age of 25. Approximately a quarter of the participants reported being very or moderately familiar with telemedicine. Furthermore, most participants (80.5%, 243) expressed their willingness to try telemedicine. The most common barriers to telemedicine practice were concerns about diagnostic reliability, resistance from physicians, and patient resistance. The study found no significant associations between participants' sociodemographic variables, their familiarity with telemedicine, and their readiness to adopt it., Conclusion: While there is a low level of awareness and knowledge regarding telemedicine among general populations in Saudi Arabia, there is generally a positive perception and willingness to adopt telemedicine for improved healthcare delivery. Addressing barriers to adopting such technology is crucial to ensure the country's successful implementation and widespread acceptance of telemedicine., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Local Committee of Bioethics at Northern Border University (HAP-09-A-043) issued approval 16-24-H. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Abd El Mawgod et al.)

Introduction Out-of-hospital cardiac arrest is one of the greatest causes of death in the world. When basic life support (BLS) techniques are performed rapidly, the odds of survival increase. The aim of this research is to assess the university students' preparation and knowledge level regarding their interest in participating in BLS. Methods A cross-sectional study using an online self-administered questionnaire was conducted between January 20 and March 20, 2022. The questionnaire addressed awareness about BLS, willingness to participate in such courses, perceived barriers and incentives, and course uptake, in addition to the sociodemographic profile of participants. Logistic regression analysis was used to identify the factors significantly associated with the willingness to participate in BLS courses and the associations are reported as adjusted odds ratios (AORs) with 95% confidence intervals (CIs). Results A total of 1,546 students completed the questionnaire; almost half of them (n=761, 49.2%) were aged 17 to 21 and the majority were females (n=1,132, 73.2%). Only one-third of the population had heard about BLS (n=519, 33.6%), 27.1% (n=419) recognized where to register for BLS training, and 20.3% (n=314) had taken a BLS course. Most participants (n=1,081, 69.9%) demonstrated a low level of awareness. Conversely, a substantial portion (n=1,204, 77.9%) expressed a personal interest in undertaking the course. It was observed that participants who are affiliated with healthcare specialties (AOR = 5.96, 95% CI = 4.66-7.63, p<0.05) exhibited greater knowledge about BLS, while females (OR = 2.49, 95% CI = 1.52-4.08, p<0.05) and those in healthcare specialties (OR = 2.23, 95% CI = 1.29-3.82, p<0.05) displayed a notably higher inclination to enroll in BLS courses compared to their counterparts. Conclusion Despite the limited awareness of BLS among university students, there is a strong willingness to engage in BLS courses. It is crucial to motivate students to partake in these courses and emphasize the availability of accredited centers for their education institutes., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Review Board of Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia issued approval 22-0031. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alzelfawi et al.)

Background The advent of clear aligners represents a significant shift in orthodontic treatment, offering an aesthetic and convenient alternative to traditional braces and helping maintain better oral hygiene as it is removable. This study investigates the awareness and perception of clear aligners among dental, medical, and paramedical students in Belagavi, India. Methodology A cross-sectional, observational study was conducted in February 2024 among students from a private medical university in Belagavi. A validated questionnaire (content validity ratio = 0.88; Cronbach's alpha coefficient = 0.86), developed through expert consultation and pilot testing, assessed the awareness and perception of students on clear aligners. Simple random sampling was used to select 480 participants. Data were analyzed using the chi-square test, analysis of variance, Pearson correlation coefficient, and binary logistic regression. Results The study found that awareness and perception of clear aligners were the lowest among medical and paramedical students in comparison with dental students. A positive linear correlation was seen between awareness and perception scores. When specialty was taken into consideration, medical/dental students were 2.55 times more aware and had 2.78 times more positive perceptions toward clear aligners compared to paramedical students. Conclusions There was a notable disparity in the awareness and perception of clear aligners among dental, medical, and paramedical students. Medical and paramedical students displayed lower awareness and unfavorable perception toward clear aligners in comparison with dental students., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Research Ethics Committee KLE Vishwanath Katti Institute of Dental Sciences issued approval EC/NEW/INST/2021/2435. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Sadhunavar et al.)

Background Post-COVID-19 syndrome (PC19S) is an emerging pathological entity characterized by the development or persistence of a spectrum of symptoms and signs 12 weeks after the original disease. Most COVID-19 patients show a variety of persistent symptoms after recovery that impact their quality of life and professional performance. The prevalence of PC19S is found to be high among many populations hence, the need for knowledge and understanding of its risk factors, symptoms, and the awareness of the population about them to improve the provided health and medical care. Aim This study aims to assess the level of awareness of post-COVID-19 syndrome among the general population of the Kingdom of Saudi Arabia (KSA). Most studies have focused on hospitalized patients and those with severe disease, but PC19S can exist in other categories of COVID-19 patients; hence, the need for total population coverage. Methodology A cross-sectional study was conducted during the period between June 2023 and August 2023 using a structured self-administered online questionnaire. The online questionnaire in addition to the demographic characteristics consists of two main parts, one is about the awareness of the Saudi population of symptoms of PC19S and the other is about awareness of its risk factors. Results The majority of the participants (1558; 72.4%) showed low awareness of PC19S symptoms while only about one quarter (595; 27.6%) showed satisfactory awareness. Also, the awareness of the participants toward risk factors was low, as 1738 (80.7%) of them showed low awareness. We categorized the results into three levels of awareness to simplify and facilitate interpretation. The findings showed that 1380 individuals (64.09%) had low awareness of PC19S, 536 individuals (24.89%) had moderate awareness, and only 237 individuals (11%) had high awareness. The study reported that the highest awareness toward symptoms was of smell disturbances (1206; 56.0%) and the least was of hair loss (506; 23.5%) while among the risk factors, the highest was found toward old age 1326 (61.6%) and the female sex was the lowest 194 (9.0%). Conclusion The study revealed that the majority of the participants demonstrated low awareness of symptoms and risk factors, which needs a continuous effort to raise the population's awareness of this health-threatening condition., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. The Local Permanent Committee of Bioethics Research-University of Bisha issued approval UB-RELOC H-06-BH-087/(0705.23). Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alghamdi et al.)

Background: Endocrine-disrupting chemicals (EDCs) interfere with hormonal systems, potentially causing metabolic, reproductive, and neurological issues, as well as hormone-related cancers. Found in everyday products, EDCs accumulate in body tissues over time, with adverse effects depending on the dose and duration of exposure. This study aims to explore behaviors related to EDC exposure among Saudi citizens to assess the need for further risk reduction interventions., Methodology: This cross-sectional study employed a validated, self-administered online questionnaire to assess daily life behaviors associated with EDC exposure. A total of 563 participants were recruited using convenient sampling through online platforms., Results: The study revealed that a significant majority of participants were aged 18-25 years (48.67%, n=274). On average, participants scored 32.78 out of a maximum of 60 for potential EDC exposure, with scores ranging from 13 to 54 points. The majority (85.26%, n=480) fell into the moderate potential exposure category, while a small minority (4.26%, n=24) exhibited high potential risk based on their reported daily habits, predominantly among male participants (95.83%, n=23). A significant majority (72.65%, n=409) indicated a likelihood of adopting lifestyle changes to reduce exposure to harmful substances., Conclusion: This study reveals diverse behavioral patterns linked to endocrine disruptor exposure among the general population in Saudi Arabia. Interestingly, the participants showed a positive attitude and willingness to change their risky behaviors. These findings underscore the necessity for educational programs and public health campaigns aimed at addressing gaps in knowledge. Encouraging the public to adopt behaviors that reduce exposure is essential to minimizing the potential long-term effects of EDCs., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Research Ethics Committee of King Faisal University issued approval KFU-REC-2024-MAY-ETHICS2273. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alabdulmohsen et al.)

Aim and background Oral and maxillofacial surgery is a crucial medical specialty focused on diagnosing, treating, and preventing diseases and injuries affecting the oral cavity, jaw, and face. There is a lack of awareness about this field in the specific study area of hail. This study aimed to assess the knowledge, awareness, and perception of maxillofacial surgery among healthcare professionals and the public. Methods The study included 225 participants, consisting of dental and medical professionals and the general public in Hail, Saudi Arabia. Convenience sampling was employed, and participants needed to be at least 20 years old and residents of Hail. A validated online questionnaire, translated into Arabic, was used for data collection. Results A proportion (78.2%) of dental professionals were aware of the specialty of oral and maxillofacial surgery. Among the general population and most medical professionals, the most commonly associated procedures with maxillofacial surgery were the treatment of injuries, bone fractures, and morphological changes in the mouth, jaw, and face, reported by 85.8% of the participants. Furthermore, 60.9% of the participants believed that maxillofacial surgery was the appropriate referral for cleft lip correction. Conclusion The study highlighted significant knowledge about the role of oral and maxillofacial surgeons among the target population. Out of the 225 participants, 137 participants (60.9%) chose the specialty of maxillofacial surgery for surgical intervention to treat cleft lips. Moreover, 75.1% (n = 169) of the participants had previously heard about oral and maxillofacial surgery, while 24.9% (n = 56) had never heard of this specialty. The findings also showed that 189 participants were not aware that a maxillofacial surgeon is responsible for treating severe deformities that cannot be eliminated using orthodontics, such as growth disorders, hypoplasia and hypoplasia of the lower jaw, and asymmetry of the lower jaw (prognathism and retrognathism of the jaw). To bridge this knowledge gap, it is crucial to implement targeted educational initiatives and awareness campaigns among both the general population and healthcare professionals. By increasing awareness and understanding of the specialized role of oral and maxillofacial surgeons, patient care can be optimized, and appropriate referrals to these specialists can be ensured. Clinical significance This study shows the importance of increasing awareness of oral and maxillofacial surgery among health professionals and the general public. Improved understanding of this specialty can lead to better patient outcomes and early referrals., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Research Ethics Committee at University of Hail issued approval H-2023-362. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Elnaem et al.)

Background/objective:  The detrimental effects of smartphone addiction impair hand functions and pinch strength. One prominent issue is the occurrence of "smartphone pinky," which leads to dysfunction and pain in the fifth finger. This study aims to assess the level of awareness regarding smartphone pinky and its associated risk factors among the population of the Eastern Provinces., Methods:  This cross-sectional study was carried out on 500 participants from the Eastern Province of Saudi Arabia. Participants voluntarily took part in the research, which spanned from July 2023 to February 2024. Data collection was carried out using a semi-structured questionnaire designed to gauge awareness of smartphone pinky and its contributing factors within the Eastern Province population., Results:  The study included 500 participants. This study showed that about half of the participants (48.8%) use smartphones for five to eight hours during the day. Moreover, about two-thirds of them (64.6%) held the smartphone in the wrong way. The majority of participants 74.4% have not heard about the smartphone pinky. Also, the results reveal that less than half of the participants (45.8%) think that the smartphone pinky can affect daily life., Conclusions:  This study concluded that the majority of participants have not heard about smartphone pinky and do not have awareness of the risk factors of smartphone use., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Research Ethics Committee at King Faisal University, Al Hofuf, Saudi Arabia issued approval KFU-REC-2024-MAR-ETHICS2047. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Aldanyowi et al.)

Background Pediatric obstructive sleep apnea (POSA) is a common sleep disorder that can cause major health problems if untreated. Parental knowledge and awareness are critical for early detection and management of POSA in children. This study sought to measure parents' and caregivers' knowledge and awareness of pediatric POSA in Jazan, Saudi Arabia, as well as to uncover sociodemographic correlates of knowledge levels. Methods This cross-sectional study was conducted in Jazan, Saudi Arabia. A structured survey was used to collect data on sociodemographic factors and knowledge of pediatric OSA. Data were examined using descriptive statistics, ANOVA, and multivariate logistic regression analysis. Results The study included 393 parents and caregivers, 36.4% of whom were in the 18-30 year age group. Most were Saudis (n=385; 98%), and 212 (53.9%) were men. Most parents (n=378; 96.2%) had limited knowledge of pediatric OSA. Significant knowledge gaps were observed in recognizing POSA symptoms, understanding its impact on children's academic performance, and their association with mental health issues. Internet and social networking sites were the most common sources of knowledge about POSA (n=131; 33.33%), followed by knowing someone with OSA (n=103; 26.21%). Parents with more than eight children had a significant association with more knowledge than those without children (adjusted OR = 10.661, 95% CI: 1.367-83.139, p = 0.024). Conclusion The study identified significant gaps in the recognition of POSA symptoms and understanding its impact on their children's academic performance and mental health. Despite their limited knowledge, parents were receptive to early intervention for POSA. The study suggests that parents with more children had better knowledge of POSA, indicating that experiential learning may contribute to their understanding. The study recommends developing and assessing targeted education and awareness programs for parents, healthcare providers, and the public to improve POSA diagnosis, care, and outcomes., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Standing Committee for Scientific Research - Jazan University (HAPO-10-Z-001) issued approval 45/11/1113. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Al-Makramani et al.)

Introduction Globally, suicide remains a major public health problem and is the second most common cause of death in the 15-45 years age group. Awareness about suicide and the attitude of healthcare professionals regarding suicide are crucial factors determining the care for suicidal behaviors. The present study aimed to compare suicide literacy and attitude toward suicide between doctors and nurses and to explore the association between suicide literacy and attitude toward suicide. Methods A cross-sectional comparison study was conducted between doctors and nurses in a tertiary healthcare center in southern India. The demographic characteristics and work and suicide care experience were recorded using a semi-structured proforma. Literacy of Suicide Scale - Short Form (LOSS-SF) and Attitude Toward Suicide Questionnaire (ATTS) were used to assess the awareness about suicidal behaviors and attitudes toward suicide, respectively. Appropriate statistical tests were used to compare the outcome measures between doctors and nurses with the statistical significance set at p ≤ 0.05. Results A total of 600 healthcare professionals (doctors (n=300) and nurses (n=300)) were included. The doctors were older, had longer work experience, and demonstrated better suicide literacy, yet harbored more negative attitudes toward suicide than nurses. Among doctors, increasing levels of suicide literacy were negatively correlated with positive attitudes toward suicide. Among nurses, increasing age was negatively correlated with healthy attitudes toward suicide. Conclusion Doctors had better awareness of suicidal behaviors yet displayed negative attitudes toward people with suicidal behaviors. Despite having less suicide awareness, nurses exhibited positive attitudes toward suicide. Suicide literacy and attitudes toward suicide can have complex relationships mediated by multiple factors., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Human Ethics Committee of Mahatma Gandhi Medical College and Research Institute, Puducherry, India issued approval MGMCRI/PGD/02/2019/06. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Jandial et al.)

Introduction Vitamin D, essential for various bodily functions, exists as D2 and D3, synthesized from plant and animal sources. Deficiency, linked to reduced intake, sun exposure, or metabolic disorders, poses health risks like diabetes and cardiovascular diseases. Management includes fortification, supplements, and individual assessment to avoid toxicity. Our study aimed to assess the public awareness of vitamin D deficiency in Qassim, Saudi Arabia, examining its relationship with sociodemographic factors. Methodology This cross-sectional study was conducted in the Qassim Region, Saudi Arabia, employing convenient non-probability sampling among a population of 375 individuals. Data collection was facilitated through a validated questionnaire, and subsequent coding, data entry, and analysis were executed using IBM SPSS Statistics for Windows, Version 27.0 (Released 2020; IBM Corp., Armonk, NY, USA). Results Our study included 375 adults in Qassim, Saudi Arabia, revealing varying vitamin D deficiency awareness levels. Most were women (n = 204, 54.4%) residing in urban areas (n = 293, 78.1%). At the same time, 77.6% (n = 291) had prior knowledge of vitamin D and fewer practiced habits conducive to its synthesis, with 47.7% (n = 179) including vitamin D-rich foods and 39.2% (n = 147) exposing themselves to sunlight. Family/friends (n = 99, 26.4%) were the primary information source. Participants scored (n = 183, 48.8%) good or high on vitamin D awareness. Education level (p = 0.028), urban residence (p = 0.001), employment status (p = 0.032), and income (p = 0.001) significantly influenced awareness, and gender, age, and marital status showed no significant associations with vitamin D awareness. Conclusion Our study shows that the majority have prior knowledge of vitamin D, yet significant gaps exist in awareness of vitamin D deficiency among adults in Qassim, Saudi Arabia. Education, urban residence, employment, and income were critical determinants of awareness, underscoring the need for targeted educational interventions. There is a need to provide information about vitamin D and its other aspects through various media, such as television and social platforms., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Qassim Regional Ethics Committee issued approval 607-45-7073. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Almutairi et al.)

Background Organ donation is a community service that not only saves lives but also improves the quality of life. The major concerns causing organ shortage in the country are the lack of awareness and correct knowledge among the public and myths and misconceptions clouding organ donation because of religious and cultural barriers. Material and methods A cross-sectional study was conducted among 300 medical students of a private medical college in the Telangana region, India, from July 2019 to October 2019 after approval from the Institutional Ethics Committee (IEC). A total of 300 participants (218 females (72.66%) and 82 males (27.33%)) were included in the study. Respondents completed a three-section questionnaire that included sociodemographic data, 15 questions on knowledge, and 12 questions on the attitude and ethical aspects of organ donation. Statistical tests utilized for investigation were the Student's t-test and one-way ANOVA to compare knowledge and attitude scores. Results The mean knowledge score among the participants was 10.85±1.79, with a P value of 0.45. The mean attitude score concerning organ donation among the participants was 45.5±4.47, with a P value of 0.44. The majority (87.1%) showed a positive attitude in this study. Conclusions The study emphasizes the necessity of interdisciplinary educational interventions for medical students to help them realize the complexities of the problem holistically. Their attitude regarding organ donation is not significantly affected by traditional educational interventions such as lectures and demonstrations. Educated healthcare professionals will play a critical role in motivating the public for the cause of organ donation promotion., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Ethics Committee Mamata Medical College issued approval IEC/IRB No.26/MMC/2019. Recommended . Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Vinay et al.)

Background Falls, particularly common among the elderly, pose significant health risks and mortality rates worldwide. Factors such as decline related to old age, gender, medical conditions, and environmental hazards contribute to falls. Prevention strategies focus on environmental modifications, exercise programs, medication reviews, and vitamin D supplementation to reduce fall risks and improve outcomes. This study aims to investigate the awareness of fall risk and measures of fall prevention among older adults in Buraidah, Qassim, Saudi Arabia, and examines the relationship between the level of awareness and various sociodemographic factors. Methodology This cross-sectional study was conducted among elderly patients at primary healthcare centers in Buraidah, Qassim province, Saudi Arabia. Data were collected via an interviewer-administered questionnaire assessing awareness and prevention of falls. Data were cleaned in Excel (Microsoft Corp., Redmond, WA, USA) and analyzed using SPSS version 29 (IBM Corp., Armonk, NY, USA). A linear regression model was used to determine the association. Statistical significance was established at a p-value of 0.05 or lower. Results Our study included 280 elderly participants, of whom 58.2% were female. The mean age was 63.7 years (SD = 4.9), and 34.6% had a bachelor's degree. Regarding fall awareness, 81.4% acknowledged preventability. Notable preventive measures included medication reviews (64.6%), eye examinations (85.7%), physical activity (82.2%), vitamin D supplementation (76.8%), and home safety devices (97.5%). Regarding fall prevention, 61.8% underwent medical examinations annually, and 65.4% had vision checkups. Higher awareness about fall risks was associated with female gender (β = 1.394, 95% confidence interval (CI) = 0.199 to 2.589, p = 0.022), higher education (β = 0.931, 95% CI = 0.549 to 1.314, p < 0.001), and chronic diseases (β = -1.935, 95% CI = -3.313 to -0.556, p = 0.006). Conclusions Our study demonstrates significant awareness among elderly participants regarding fall preventability and measures. Females and those with higher education levels had higher levels of awareness. These findings highlight the importance of targeted interventions to increase awareness and preventive measures among elderly populations., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Regional Research Ethics Committee, Al Qassim Region issued approval 607/45/3772. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Almesned et al.)

Introduction Digestive disorders, affecting 70 million people globally, have gained attention. Gastroesophageal reflux disease (GERD) causes heartburn and acid regurgitation. Factors like obesity, poor diet, and lifestyle influence its prevalence. GERD rates are higher in Saudi Arabia than in Western and East Asian countries, highlighting the need for local awareness, our study aims To assess the prevalence of local habits and risk factors of patients with GERD in the Southwest region of Saudi Arabia. Method This prospective descriptive cross-sectional online-based study included 372 individuals from the Southwest Region, Saudi Arabia. The study was conducted using a self-administrated online questionnaire to collect the data for the targeted participants. After obtaining consent to carry out the study, the data were collected and computerized using Microsoft Excel, to form a database using all the items from the data collecting sheets. Data was then encoded and analyzed using Statistical Package for Social Sciences (SPSS) software, version 27 (IBM Corp., Armonk, NY). Data was displayed and presented in the form of tables and charts Results This study included 372 individuals, predominantly Saudi 98.7%, n=367. The most common age group was 21-25 years (32.5%, n=121), followed by those over 40 (18.5%, n=69). Participants were mainly from Al-Qunfudhah and Haly 27.2%, n=101. Most were single (49.5%, n=184) or married (48.4%, n=180), with a bachelor's degree 66.7%, n=248. Employees comprised (36.3%, n=135), and students 30.9%, n=115. Only 2.7%, n=10 were pregnant. Nearly half (48.4%, n=180) had a monthly income below 5,000 SAR. Most participants weighed 40-60 kg (41.4%, n=154) and were 150-160 cm tall (47%, n=175). The prevalence of GERD was 16.1%, n=60. Significant associations were found between GERD diagnosis and meal type, smoking, family history, and high pickle and salt intake (P-values: 0.002073, 0.000607, <0.00001, and 0.008557, respectively). Conclusion This study can conclude that the prevalence of GERD is not high in the Southwest region of Saudi Arabia. Significant risk factors regarding patients' habits should be taken into consideration and diminishing them in order to decrease the incidence of the disease and improve the quality of life of already diagnosed patients., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Biomedical Research Ethics Committee at Umm Al-Qura University issued approval HAPO-02-K-012-2024-02-2018. The Biomedical Research Ethics Committee has evaluated and examined the above-mentioned research proposal and has found it to be in accordance with the specifications and conditions of the ethics of scientific research. The Committee has accordingly granted the Principal Investigator final approval concerning the ethics of scientific research. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alshaikhi et al.)

Background: The term "cellulitis" is frequently used to describe a non-necrotizing inflammation of the skin and subcutaneous tissues that is typically caused by an acute infection and does not affect the muscles or fascia. Warmth, erythema, tenderness, swelling, and localized pain are the hallmarks of cellulitis. Life-threatening and debilitating outcomes from cellulitis include necrotizing fasciitis, necrotizing hypodermitis, abscess formation, septic shock, and, in extreme cases, death. The current study aimed to assess public awareness of cellulitis in the Al-Qunfudhah region, Saudi Arabia., Methods: A descriptive cross-sectional study was conducted targeting all residents in Al-Qunfudhah, Saudi Arabia, during the period from January to March 2024. Data were collected using a pre-structured online questionnaire. The study questionnaire included participants' demographic data, cellulitis data, and knowledge and attitude towards cellulitis. The final questionnaire was uploaded online using social media platforms by the researchers and their friends until no more new participants were included., Results: A total of 470 records were analyzed. Among the respondents, the majority were male (n=347, 73.8%), and the highest proportion fell within the age range of 18 to 25 years (n=174, 37.0%). The highest proportion of respondents correctly identified cellulitis as a medical condition affecting the skin and soft tissues underneath it, typically caused by infection or injury (n=278, 59.1%). Additionally, the majority acknowledged that cellulitis can cause pain, swelling, and redness in the affected area (n=240, 51.1%). As for factors associated with awareness of cellulitis, significant associations were found with age group (p=0.031), educational levels (p=0.003), and employment status (p=0.002)., Conclusions: This study revealed a high level of awareness of cellulitis among participants, especially highly educated and employed participants. Participants believed that healthcare providers play a crucial role in raising population awareness of cellulitis health problems., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Biomedical Research Ethics Committee of Umm Al-Qura University issued approval HAPO-02-K-012-2024-02-1980. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Taha et al.)

Objective: This study investigates the prevalence and determinants of awareness of precision medicine among a nationally representative sample of individuals with self-reported depression and anxiety in the United States.", Methods: Data were obtained from the Health Information National Trends Survey (HINTS) 5, Cycle 4, which is a study administered by the National Cancer Institute and is nationally representative. The survey, conducted between February and June 2020, targeted non-institutionalized, civilian US adults aged 18 years and older. Utilizing survey-weighted logistic regression, predictors of precision medicine awareness were assessed, encompassing sociodemographic, health-related, and technological factors., Results: Among 890 individuals with self-reported depression and/or anxiety, approximately 15.3% reported awareness of precision medicine. Participants who had a higher level of education and those who had increased health-linked social media usage were three times more likely to be aware of precision medicine compared to those who did not. Old age was also positively associated with increased awareness., Conclusion: The present study's findings have disclosed an alarming lack of awareness of precision medicine, particularly among mentally ill persons with anxiety or depression, in which the targeted subgroups, including individuals with lower education levels and limited health-linked social media utilization, indicated lower levels of awareness. As such, it is recommended that such disparities be tackled using customized interventions along with educational initiatives, as this is likely to improve awareness levels while also ensuring equitable and increased access to precision medicine within the context of mental health., Competing Interests: Human subjects: All authors have confirmed that this study did not involve human participants or tissue. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Ojo et al.)

Background The thyroid gland is responsible for regulating many aspects of body functions. Despite their global prevalence, thyroid disorders often go underdiagnosed, which can lead to serious health complications. In Saudi Arabia, the overall prevalence was 49.76%, among which subclinical hypothyroidism was the most prevalent type. Raising awareness and knowledge about thyroid diseases and their risk factors is essential for the prevention and early treatment of these disorders. Aim and objectives To assess the awareness of thyroid diseases and their risk factors among the residents of Jeddah, Saudi Arabia, as well as understand their attitudes and underlying influencing factors toward thyroid health. Methods A cross-sectional study was conducted in Jeddah, Saudi Arabia, from January 2023 to December 2023. The study included a diverse sample of Saudi and non-Saudi participants aged 18 to 65 years. A self-administered online questionnaire translated into Arabic was used to collect information. Results The study involved 393 participants, 72.5% female and 27.5% male. Most participants held a bachelor's degree or higher (78.1%). Hypothyroidism was the most prevalent diagnosed thyroid disease (14.0%). Only 20% of participants had good knowledge. Respondents were relatively less aware of the risks associated with pregnancy and the postpartum period (35%), medications such as amiodarone (26%), eating soya beans (22%), and gastrointestinal tract (GIT) symptoms of thyroid diseases (36%). Attitudes toward thyroid health were generally negative (85.5%). However, a significant association was noted between a history of thyroid disease and a positive attitude (p = 0.002). Educational level and employment status were strong determinants of knowledge levels (p = 0.036 and 0.005, respectively). A positive correlation was found between knowledge levels and attitudes (r = 0.321, p < 0.001). Conclusion The study showed a low level of awareness among participants living in Jeddah, especially the unemployed and those with low levels of education. Their unawareness of the possible risks of thyroid diseases during pregnancy should be thoroughly addressed by public campaigns., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Research Review Board at Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia, issued approval IRRB-01-30112023. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alharazi et al.)

Objectives: This study aimed to evaluate the awareness regarding lead poisoning among the Saudi population of Arar, Saudi Arabia., Methods: A cross-sectional, online self-administered questionnaire-based method was utilized for data collection through convenience sampling from Arar, Saudi Arabia. The collected data were analyzed using descriptive and inferential statistics., Results: The study included 389 participants, with a majority (302 participants (77.6%)) of females with a mean age of 31.7 years (range 18-54 years). The source of information about lead poisoning was reported as the media in 264 participants (67.8%). The participants (197, 50.6%) reported children as the age group most at risk for lead poisoning. All suggested sources of exposure to lead were identified by 190 participants (48.9%). As for the most common effect of lead poisoning, mental impairment was reported by 101 participants (26%), while 107 (27.6%) participants reported nerve problems. Kidney problems were reported by 181 participants (46.4%). Gender significantly (P = 0.001) affects the participants' knowledge about the sources of lead poisoning, while knowledge about the routes of poisoning was significantly affected by the participants' age (P = 0.010)., Conclusion: In Saudi Arabia, there is limited knowledge of risk factors, route of poisoning, and management and prevention of lead poisoning. A comprehensive lead-poisoning prevention strategy must include a high level of public knowledge of lead hazards as a key component., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Northern Border University Bioethics Committee issued approval 70/44/H. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Elmorsy et al.)

Background: Basal cell carcinoma (BCC) stands as the most common skin malignancy, with its high incidence rate and associated costs rising annually. The origin of BCC is related to environmental, genetic, and phenotypic factors. Among these, the most important risk factor is exposure to UV light triggering keratinocyte carcinogenesis, causing cumulative cellular damage that leads to BCC development. Individuals' educational background and awareness of skin cancer risk factors may influence the development of BCC. Lack of knowledge about risk factors (like chronic UV exposure, sunburn, artificial solar beds, and fair skin color), prevention methods, and jobs involving outdoor activities may be associated with BCC formation., Aim: The aim of the study was to analyze recent trends and the risk factors associated with BCC, while also revealing any potential link between BCC and the patient's education level and awareness of skin cancer risk factors., Design and Methods: A hospital-based case-control study was conducted, involving a total of 141 individuals. Among them, 47 were clinically and histologically confirmed BCC patients, while the remaining participants served as controls. The control group comprised 94 individuals matched for age and gender. Data on various factors including gender, age, residency, education level, Fitzpatrick skin type, outdoor activities, use of solariums, and UV therapy, as well as awareness of potential BCC triggers, were collected using an adapted questionnaire and subjected to analysis. The collected data underwent statistical evaluation., Results: Most of the BCCs (n = 52; 71.2%) were located in sun-exposed areas (p < 0.001), with a female/male ratio of 1.35 to 1. The nodular type of BCC was the most common form (n = 49; 67.2%). The percentage of patients in the study group with Fitzpatrick phototypes I and II (n = 38; 80.9%) was significantly higher than in controls (n = 50; 53.2%, p = 0.002). The percentage of persons with higher education levels (bachelor's degree, master's degree, and post-diploma) was significantly less prevalent among cases compared to controls (n = 20 (42.6%) vs. n = 58 (61.7%), respectively (p = 0.033)). Notably, BCC patients with low education levels exhibited significantly lesser awareness concerning genetic factors and chronic solar radiation.  Conclusions: Coexistence of factors, such as a medical history of skin cancer, having Fitzpatrick skin types I and II, engaging in outdoor work exposed to the sun, knowledge that genetic factors are risk factors of skin cancer, and knowledge that stress is a risk factor of skin cancer, are significant predictors of the disease. A lower level of education and limited awareness about risk factors can also be a risk factor for BCC. It is essential to raise awareness about potential triggers and preventive measures within the population to reduce the incidence of the disease., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Ethics Committee of the Scientific/Research National Center of Dermatology and Venereology issued approval 18/6. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Darjania et al.)

Background: Erectile dysfunction (ED) is defined as the inability to achieve and maintain an erection powerful enough to permit pleasurable sexual activity. There are four categories for ED grades. The illness may be influenced by vascular, neurological, psychological, and hormonal factors. Anxiety about performance and relationship issues are common psychological triggers., Aim: This study aimed to determine the prevalence, risk factors, and awareness of ED and its management in the population of Saudi Arabia., Method: This community-based, cross-sectional study was conducted among adult Saudi males in all five regions of Saudi Arabia (Central, Eastern, Western, Southern, and Northern). A self-administered questionnaire was distributed among participants using an online survey. The questionnaire includes sociodemographic data (i.e., age, region, marital status, education), medical history, and erectile function (International Index of Erectile Function (IIEF-5)) as a diagnostic tool for ED., Results: In total, 924 men took part. About 512 (55.4%) were aged between 18 and 25 years old, and nearly two-thirds (595, 64.4%) were single. The Internet was the most common source of ED information 495 (53.6%). Based on respondents' knowledge, the most common risk factor of ED was depression (561, 60.8%), while the most common treatment option was lifestyle modification (654, 70.8%). The prevalence of ED among adult Saudi men was 198 (21.4%). Independent risk factors for ED include having been married, being an employee, and previous operation of the perineum., Conclusion: ED was common among the Saudi male population. ED was more prevalent among older men with associated chronic diseases and had elevated body mass index (BMI). Having been married, being an employee, and having a previous perineum operation were identified as the significant independent risk factors for ED. Longitudinal studies are needed to determine the cause and effect of the recognized risk factors for ED among men., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Kingdom of Saudi Arabia Ministry of Education Jazan University issued approval REC-45/02/743. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Hakami et al.)

Introduction: Management of trauma involves both in-hospital and prehospital care. The level of prehospital care plays a vital role in trauma management. Low- and middle-income countries are still in the nascent stages of development of their emergency medical services (EMS) systems. Also, there have been insufficient studies assessing the availability and level of prehospital care in developing nations such as India. Therefore, we decided to study the level of awareness and prehospital care given to severe trauma patients., Materials and Methods: We conducted this prospective observational study at the emergency department of Fortis Hospital, Noida, Uttar Pradesh, in Northern India. All adults between ages 18 and 85 years presenting with severe trauma (immediate life- or limb-threatening conditions requiring emergent intervention) were included. We measured the primary outcome in terms of why people did not avail EMS. We measured secondary outcomes in terms of intervention done in patients coming to us via EMS., Results: Out of 101 patients, 89 (88.12%) were transported to Fortis Hospital through non-EMS, whereas only 12 (11.88%) patients were transported by EMS. We found the difference to be statistically significant. The major reason given for not summoning advanced trauma care services in patients was a lack of awareness about the potential benefits of EMS (n = 64 [72%]), followed by a lack of availability (n = 24 [27%]), and financial reasons (n = 1 [1.1%])., Conclusion: We conclude that the level of awareness about EMS for severe trauma patients was found to be low in our study. There is a need for an awareness-creation program across the nation to fill this gap., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. The Fortis Hospital Institutional Ethics Committee (FHIEC) issued approval FHIEC/2018/03. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Singhal et al.)