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This article discusses the association between long-term use of bisphosphonates, a common treatment for osteoporosis, and atypical femoral fractures (AFFs). While AFFs are rare, they are a serious concern due to their potential complications. The article presents a case study of a 72-year-old female who had been on alendronate therapy for 18 years and had a previous femur fracture attributed to alendronate use. The patient underwent surgery to prevent a pathological fracture and was subsequently discharged and followed up with regular monitoring. The article emphasizes the importance of early detection, discontinuation of bisphosphonates, and appropriate management to prevent AFFs and improve patients' quality of life. [Extracted from the article]