Search

Objective: To analyze the differences in chest computed tomography (CT) findings in patients infected with Omicron strain BF.7 of coronavirus disease 2019 (COVID-19) with different clinical outcomes, and to improve the understanding of COVID-19 imaging. Methods: The features of chest CT images from 126 patients infected with Omicron BF.7 strain at the People's Hospital of Inner Mongolia Autonomous Region were retrospectively analyzed, and divided into ‘group A’ (not serious) and ‘group B’ (serious) according to whether they progressed to critically ill patients. There were 103 cases in group A, including 65 males and 38 females, with an average age of (73.98±11.53) years. There were 23 patients in group B, including 16 males and 7 females, with an average age of (73.43±12.53) years old. The differences in age, gender, and chest CT lesion distribution, density, and lung lobe involvement were compared between the two groups. Results: All 126 COVID-19 patients had an epidemiological history, and there was no statistical significance in age and sexes between the two groups. The volume proportion of lesions in the upper and lower lobes of the left lung, the upper, middle, and lower lobes of the right lung, and both lungs in group B was higher than that in group A. The lesions were primarily ground glass shadow and consolidation, and the range was larger than group A. Conclusion: The age and chest CT findings of patients who developed severe COVID-19 are different from those who do not. The analysis of imaging characteristics can provide reference for clinical diagnosis, treatment, and prognostic assessment.

Objective: To analyze the differences of chest computed tomography (CT) inflammatory lesions in patients with coronavirus disease 2019 (COVID-19), which were quantitatively measured based on deep learning, to warn the occurrence of severe cases and improve the understanding of the prognosis of COVID-19. Methods: The chest CT scans of 477 local patients with COVID-19 diagnosed for the first time at Inner Mongolia Autonomous Region People's Hospital were retrospectively analyzed. A total of 276 men and 201 women were divided into group A (not serious) and group B (serious) based on whether their diseases turned serious (severe/critical). Comparison was made between the two groups on the basic CT signs, such as lesion distribution, involved lobe side, number, differences in lesion volume, volume proportion, and density based on deep learning. Results: All 477 patients with COVID-19 had epidemiological history, and no statistical difference was noted in age and gender between the two groups. The volume and proportion of the lesions in the whole lung and each lobe of the lung in group B were higher than those in group A. The lesions in group A were mainly in the lower lobe of the right lung, accounting for 3.32% more than that in other lobes. The lower lobe of the left lung was the next, accounting for 2.08%. The volume of lesions in the upper lobe of the left lung was lower than that in other lobes, accounting for only 0.25%. No lesions were noted in the upper lobe of the right lung, middle lobe of the right lung, and upper lobe of the left lung in part of group A. In group B, the lesions were distributed in both lungs and in each lung lobe. The lower lobes of the right lung and left lung were predominant, accounting for 57.86% and 54.76%, respectively. The volume of the middle lobe of the right lung was 34.73% compared with the other lobes. The main lesions in each group were ground-glass density shadows, and the main lesions in group A were −570 ~ −470 HU density, accounting for 13.89%, followed by −470 ~ −370 HU, accounting for 11.07%. Only 3.22% and 4.75% of solid lesions with densities of 30 ~ 70 HU and −70 ~ 30 HU were found. Most of the lesions in group B were ground-glass density shadows, and the focal densities were mainly −570 ~ −470 HU, −470 ~ −370 HU, and −370 ~ −270 HU, accounting for 13.18%, 12.58%, and 12.52%, respectively. No statistical difference was noted between the proportion of lesions with a density of −570 ~ −470 HU and that of group A; however, the volume and proportion of other lesions with different densities were higher than those of group A, showing a trend that the higher the density of the lesions, the higher the proportion of group B was compared with group A. Conclusion: Larger infection volume, more lesion solid components, and multiple CT signs often indicate more severe lung inflammation, which easily progresses to severe disease. Quantitative measurement of chest CT based on deep learning is helpful for the prognosis assessment of COVID-19 and the early warning of severe outcome.

Objective: This study aimed to analyze the chest computed tomography (CT) imaging features of coronavirus disease 2019 (COVID-19) in people of different ages and improve the understanding of the imaging manifestations of COVID-19. Methods: Chest CT data of 476 cases with COVID-19 were retrospectively analyzed, including 275 males and 201 females. The patients were divided into four groups according to different age groups: groups A (0~45 years old) 33, B (45~60 years old) 72, C (60~75 years old) 203, and D (over 75 years old) 168. A comparison was made between the four groups of patients with chest CT lesions involving lobe side, number and density, distribution, and other basic CT signs, as well as differences in lesion volume, volume proportion, and density based on deep learning. Results: All the 476 patients with COVID-19 had an epidemiological history, and there was no statistically significant difference in sex between the groups. The lesions in the lower lobes of both lungs were the most common in the four groups. The lesions in group A were mostly located in the unilateral lung, while those in groups C and D were mostly distributed in both lungs. The volume and proportion of lesions increased with age in each group, and the distribution was mainly in the lower lobe of both lungs. In groups A, C, and D, the right lower lobe was the most common and had the largest volume and proportion, while in group B, the left lower lobe had the largest volume and proportion. Compared with group A, all indexes of group C increased, and the difference was statistically significant; the lesion volume of the right inferior lobe of the lung was statistically significant compared with group B. The volume of lesions in the left upper lobe of the lung in group D was significantly increased compared with that in groups A and B, and the volume and proportion of lesions in the whole lung, upper, middle, and lower lobes of the right lung, and the lower lobe of the left lung in group D were significantly increased compared with that in groups A, B and C, and the difference was statistically significant. In group A, the density of pure ground glass was the most common, followed by the density of mixed ground glass, and the density of solid change was rare. The solid density of lesions in group D was more common, most of which showed mixed ground glass density. The incidence of pure ground glass, mixed ground glass, and solid density lesions was higher in groups B and C than that in groups A and D. The lesion density in each group was mainly ground glass density, and the CT value ranged from −570 to −470 HU and −470 to −370 HU. The lesion volume in each CT value range of group D was higher than that in groups A, B, and C, and the volume proportion was higher than that in group A, and the difference was statistically significant. Conclusion: All patients with COVID-19 in this group have an epidemiological history. Being familiar with chest CT features of people of different ages can make clinical diagnosis and treatment more targeted and provide a reference for COVID-19 disease monitoring and individualized prevention and treatment measures.

Objective: To analyze the relationship between chest computed tomography (CT) findings and clinical typing of omicron variant strains of coronavirus disease 2019 (COVID-19) at different ages, so as to improve the understanding of the imaging manifestations of COVID-19. Methods: Chest CT data of 75 patients with COVID-19 were retrospectively analyzed, including 40 males and 35 females, with an average age of (46.2±17.2) years. They were divided into groups A, B, and C based on different age groups. The differences in chest CT lesion distribution, lobular involvement, number and density, and clinical classification among the three groups were compared. Results: All 75 patients infected with the omicron variant had an epidemiological history, and no statistically significant difference was noted in gender among all clinical types. The mean age of patients with severe and critical symptoms was higher than that of patients with mild and common symptoms, and the distribution in the upper lobe of the left lung, upper lobe of the right lung, and middle lobe of the right lung was higher than that of the common type. In patients with severe symptoms, the distribution of lesions in the left lower lobe and both lungs was higher than that in the common type. The lesions were mainly ground glass opacity and consolidation. The proportion of severe and critical type increased in groups A, B and C, and the lesion range was larger than that of the common type. Conclusion: All patients with COVID-19 who were infected with the omicron variant have an epidemiological history. The clinical classifications and chest CT signs of patients in different age groups have certain characteristics, and familiarity with these characteristics can help predict severe COVID-19.