1. Characterization of Dicarboxylic Salts of Protonated Triethylenetetramine Useful for the Treatment of Copper-Related Pathologies
- Author
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Garth J. S. Cooper, Grant R. Allen, Peter D. W. Boyd, Tilo Söhnel, Kathrin Wichmann, and and Anthony R. J. Phillips
- Subjects
Aqueous solution ,Hydrogen bond ,Inorganic chemistry ,Protonation ,General Chemistry ,Crystal structure ,Condensed Matter Physics ,Thermogravimetry ,chemistry.chemical_compound ,chemistry ,Triethylenetetramine ,Polymer chemistry ,Molecule ,General Materials Science ,Amine gas treating - Abstract
X-ray crystal structures of three salts of protonated triethylenetetramine, (H4TETA)4+, with succinate, maleate, and fumarate anions are reported. Structures of the complexes (H4-triethylenetetramine)(hydrogenmaleate)4·2H2O [(H4TETA)(Hmal)4·2H2O] (1), (H4-triethylenetetramine)(hydrogenfumarate)4·3.3H2O [(H4TETA)(Hfum)4·3.3H2O] (2), and (H4-triethylenetetramine)(succinate)2 [(H4TETA)(suc)2] (3) all form assemblies of alternating two-dimensional layers of (H4TETA)4+ and the anionic species via hydrogen-bond networks. Both classical and nonclassical hydrogen bonds between the protonated amine groups, anions, and water molecules were observed. X-ray powder diffraction measurements, differential thermal analysis/thermogravimetry, density vapor sorption, and Karl Fischer titration measurements were performed to obtain confirmatory information about the water content in the structures 1 and 2 and to examine polymorphism within the salts. The nonhydrated salt 3 was determined to be the most favorable salt formula...
- Published
- 2007