1. Current commercial dPCR platforms: technology and market review.
- Author
-
Tan, Li Ling, Loganathan, Nitin, Agarwalla, Sushama, Yang, Chun, Yuan, Weiyong, Zeng, Jasmine, Wu, Ruige, Wang, Wei, and Duraiswamy, Suhanya
- Subjects
POLYMERASE chain reaction ,MOLECULAR diagnosis - Abstract
Digital polymerase chain reaction (dPCR) technology has provided a new technique for molecular diagnostics, with superior advantages, such as higher sensitivity, precision, and specificity over quantitative real-time PCRs (qPCR). Eight companies have offered commercial dPCR instruments: Fluidigm Corporation, Bio-Rad, RainDance Technologies, Life Technologies, Qiagen, JN MedSys Clarity, Optolane, and Stilla Technologies Naica. This paper discusses the working principle of each offered dPCR device and compares the associated: technical aspects, usability, costs, and current applications of each dPCR device. Lastly, up-and-coming dPCR technologies are also presented, as anticipation of how the dPCR device landscape may likely morph in the next few years. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF