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17 results on '"Guervilly, Christophe"'

1. Avdoralimab (Anti-C5aR1 mAb) Versus Placebo in Patients With Severe COVID-19: Results From a Randomized Controlled Trial (FOR COVID Elimination [FORCE])*

Author

Carvelli, Julien, Meziani, Ferhat, Dellamonica, Jean, Cordier, Pierre-Yves, Allardet-Servent, Jerome, Fraisse, Megan, Velly, Lionel, Barbar, Saber Davide, Lehingue, Samuel, Guervilly, Christophe, Desgrouas, Maxime, Camou, Fabrice, Piperoglou, Christelle, Vely, Frederic, Demaria, Olivier, Karakunnel, Joyson, Fares, Joanna, Batista, Luciana, Rotolo, Federico, Viotti, Julien, Boyer-Chammard, Agnes, Lacombe, Karine, Le Dault, Erwan, Carles, Michel, Schleinitz, Nicolas, Vivier, Eric, Schleinitz, Nicolas, Carvelli, Julien, Gainnier, Marc, Bourenne, Jérémy, Bichon, Amandine, Le Saux, Audrey, Bouzana, Fouad, Tilmont, Antoine, Cauchois, Emi, Coularet, Charlotte, Bruder, Nicolas, Velly, Lionel, Ebbo, Mikael, Veit, Véronique, Jean, Estelle, Simeone, Pierre, Blasco, Valéry, Vely, Frédéric, Piperoglou, Christelle, Coutard, Bruno, Pastorino, Boris, Villaroel, Maria Saba, Garrido-Pradalie, Emilie, Amichi, Kahéna, Larosa, Aurélie, Blondelon, Aurélie, Inal, Imane, Amichi, Kahéna, Dhorne, Jean, Durieux, Frédérique, Brunet, Julie, Cohen, Anita, Deluca, Bénédicte, Malkoun, Richard, Dellamonica, Jean, Buscot, Matthieu, Saccheri, Clément, Carles, Michel, Demonchy, Elisa, Cua, Eric, Chirio, David, Courjon, Johan, Risso, Karine, Rigault, Marie-Christine, Gazoppi, Loïc, Salas, Virginie, Bouskila, Nadège, Touitou, Irit, Breaud, Sophie, Boughdiri, Nihed, Marrane, Guillaume, Meziani, Ferhat, Merdji, Hamid, Helms, Julie, Monier, Alexandra, Demiselle, Julien, Jandeaux, Louise-Marie, Studer, Antoine, Allam, Hayat, Thiebaut, Léonie, Hutt-Clauss, Anne, Le Dault, Erwan, Cordier, Pierre-Yves, Savini, Hélène, Clerc, Axelle, Spadoni, Sophie, Javelle, Emilie, Clerc, Axelle, Chouaki-Benmansour, Nassima, Le Garlantezec, Patrick, Le Tohic, Sarah, Allardet-Servent, Jérôme, Benarous, Lucas, Madjarian, Corinne, Aouadenne-Mesbah, Assia, Rognon, Amélie, Fraisse, Megan, Plantefeve, Gaétan, Benrezzak, Nasro, Dubief, Emeline, Chauvel, Olivia, Jamet, Charlotte, Davide Barbar, Saber, Ambert, Audrey, Lloret, Sophie, Elotmani, Loubna, Dubois, Grégory, Meyrieux, Séverine, Barthelemi, Laurie, Lehingue, Samuel, Poulet, Antoine, Bezirganyan, Kristina, Asselate, Belkacem, Provitolo, Vincent, Lacombe, Karine, Bollens, Diane, Letaillandier, Cyrielle, Tran, Christian, Sebire, Manuela, Lamarque, Julie, Deguenel-Nguyen, Anne, Desgrouas, Maxime, Jacquier, Sophie, Muller, Grégoire, Bretagnol, Anne, Mathonnet, Armelle, Benzekri, Dalila, Barbier, François, Mai-Anh, Nay, Runge, Isabelle, Kamel, Toufik, Muller, Lucie, Tellec, Sophie, Guervilly, Christophe, Papazian, Laurent, Forel, Jean-Marie, Sanz, Céline, Pinglis, Camille, Valera, Sabine, Colombini, Nathalie, Camou, Fabrice, Mourissoux, Gaelle, Guisset, Olivier, Issa, Nahéma, Pedenon-Peyrichout, Delphine, Delaune, Jean, Langlade, Claire, Pedeboscq, Stéphane, Lescure, Xavier, Isernia, Valentina, Bachelard, Antoine, Fleurot, Odile, Le Gac, Sylvie, Da Conceicao, Olivia, Julia, Zelie, Chalal, Lynda, Oualit, Lynda, Kramer, Laura, Le Grand, Jennifer, Poissy, Julien, Nseir, Saadalla, Mariller, Laure, Delcoutre, Claire, Brice, Sylvie, Lelievre, Jean-Daniel, Gallien, Sébastien, Cotellon, Christine, Vindrios, William, Melica, Giovanna, Natella, Pierre-André, Bourhis, Marion, Thiemele, Alaki, De Nailly, Delphine Lefebvre, Malvy, Denis, Desclaux, Arnaud, Ducours, Mailys, Perreau, Pauline, Boyer, Alexandre, Clouzeau, Benjamin, Bui, Hoang-Nam, Bourgoin, Nicolas, Kabala, Anna, Ghezzoul, Bellabes, Servant, Vincent, and Djabarouti, Sarah

Published
2022
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3. Impact of Prone Position in COVID-19 Patients on Extracorporeal Membrane Oxygenation*

Author

Massart, Nicolas, Guervilly, Christophe, Mansour, Alexandre, Porto, Alizée, Flécher, Erwan, Esvan, Maxime, Fougerou, Claire, Fillâtre, Pierre, Duburcq, Thibault, Lebreton, Guillaume, Para, Marylou, Stephan, François, Hraiech, Sami, Ross, James, Schmidt, Matthieu, Vincentelli, André, Nesseler, Nicolas, CHU Pontchaillou [Rennes], Hôpital Yves LE FOLL [Saint-Brieuc], Centre d'études et de recherche sur les services de santé et la qualité de vie (CEReSS), Aix Marseille Université (AMU), Hôpital Nord [CHU - APHM], Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital de la Timone [CHU - APHM] (TIMONE), Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Lille, Université de Lille, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut de cardiologie [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Hôpital Marie-Lannelongue, University of California [Davis] (UC Davis), University of California (UC), Nutrition, Métabolismes et Cancer (NuMeCan), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Extracorporeal Membrane Oxygenation for Respiratory Failure and/or Heart failure related to Severe Acute Respiratory Syndrome Coronavirus 2 (ECMOSARS) Investigators: Olivier Fouquet, Marc Pierrot, Sidney Chocron, Guillaume Flicoteaux, Philippe Mauriat, Hadrien Roze, Alexandre Ouattara, Olivier Huet, Marc-Olivier Fischer, Claire Alessandri, Raphel Bellaïche, Ophélie Constant, Quentin De Roux, André Ly, Arnaud Meffert, Jean-Claude Merle, Lucile Picard, Elena Skripkina, Thierry Folliguet, Nicolas Mongardon, Antonio Fiore, Nicolas D'ostrevy, Marie-Catherine Morgan, Maxime Nguyen, Pierre-Grégoire Guinot, Lucie Gaide-Chevronnay, Nicolas Terzi, Gwenhaël Colin, Olivier Fabre, Arash Astaneh, Justin Issard, Elie Fadel, Dominique Fabre, Antoine Girault, Iolande Ion, Jean Baptiste Menager, Delphine Mitilian, Julien Guihaire, Olaf Mercier, Jacques Thes, Jerôme Jouan, Thibault Duburcq, Valentin Loobuyck, Sabrina Manganiello, Mouhammed Moussa, Agnes Mugnier, Natacha Rousse, Olivier Desebbe, Roland Henaine, Matteo Pozzi, Jean-Luc Fellahi, Jean-Christophe Richard, Zakaria Riad, Laurent Papazian, Matthias Castanier, Charles Chanavaz, Cyril Cadoz, Sebastien Gette, Guillaume Louis, Erick Portocarrero, Philippe Gaudard, Kais Brini, Nicolas Bischoff, Antoine Kimmoun, Bruno Levy, Mathieu Mattei, Pierre Perez, Alexandre Bourdiol, Yannick Hourmant, Pierre-Joachim Mahé, Bertrand Rozec, Mickaël Vourc'h, Stéphane Aubert, Florian Bazalgette, Claire Roger, Sophie Provenchere, Pierre Jaquet, Brice Lortat-Jacob, Pierre Mordant, Patrick Nataf, Juliette Patrier, Morgan Roué, Romain Sonneville, Alexy Tran-Dinh, Paul-Henri Wicky, Charles Al Zreibi, Bernard Cholley, Yannis Guyonvarch, Sophie Hamada, Claudio Barbanti, Anatole Harrois, Astrid Bertier, Jordi Matiello, Thomas Kerforne, Corentin Lacroix, Nicolas Brechot, Juliette Chommeloux, Alain Combes, Jean Michel Constantin, Cosimo D'alessandro, Pierre Demondion, Alexandre Demoule, Martin Dres, Muriel Fartoukh, Guillaume Hekimian, Charles Juvin, Pascal Leprince, Guillaume Fadel, David Levy, Charles Edouard Luyt, Marc Pineton de Chambrun, Thibaut Schoell, Roxane Nicolas, Maud Jonas, Charles Vidal, Nicolas Allou, Salvatore Muccio, Dario Di Perna, Bruno Mourvillier, Vito-Giovanni Ruggieri, Amedeo Anselmi, Karl Bounader, Yoann Launey, Thomas Lebouvier, Alessandro Parasido, Florian Reizine, Philippe Seguin, Emmanuel Besnier, Dorothée Carpentier, Thomas Clavier, Anne Olland, Pierre-Emmanuel Falcoz, Marion Villard, Fanny Bounes, François Labaste, Vincent Minville, Antoine Guillon, Yannick Fedun, and MORNET, Dominique

Subjects
[SDV] Life Sciences [q-bio], critical care, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV]Life Sciences [q-bio], prone position, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, acute respiratory distress syndrome, extracorporeal membrane oxygenation, mechanical ventilation, Critical Care and Intensive Care Medicine, mortality
Abstract

International audience; Objectives: Prone positioning and venovenous extracorporeal membrane oxygenation (ECMO) are both useful interventions in acute respiratory distress syndrome (ARDS). Combining the two therapies is feasible and safe, but the effectiveness is not known. Our objective was to evaluate the potential survival benefit of prone positioning in venovenous ECMO patients cannulated for COVID-19-related ARDS.Design: Retrospective analysis of a multicenter cohort.Patients: Patients on venovenous ECMO who tested positive for severe acute respiratory syndrome coronavirus 2 by reverse transcriptase polymerase chain reaction or with a diagnosis on chest CT were eligible.Interventions: None.Measurements and main results: All patients on venovenous ECMO for respiratory failure in whom prone position status while on ECMO and in-hospital mortality were known were included. Of 647 patients in 41 centers, 517 were included. Median age was 55 (47-61), 78% were male and 95% were proned before cannulation. After cannulation, 364 patients (70%) were proned and 153 (30%) remained in the supine position for the whole ECMO run. There were 194 (53%) and 92 (60%) deaths in the prone and the supine groups, respectively. Prone position on ECMO was independently associated with lower in-hospital mortality (odds ratio = 0.49 [0.29-0.84]; p = 0.010). In 153 propensity score-matched pairs, mortality rate was 49.7% in the prone position group versus 60.1% in the supine position group (p = 0.085). Considering only patients alive at decannulation, propensity-matched proned patients had a significantly lower mortality rate (22.4% vs 37.8%; p = 0.029) than nonproned patients.Conclusions: Prone position may be beneficial in patients supported by venovenous ECMO for COVID-19-related ARDS but more data are needed to draw definitive conclusions.

Published
2022

5. Impact of Prone Position in COVID-19 Patients on Extracorporeal Membrane Oxygenation.

Author

Massart, Nicolas, Guervilly, Christophe, Mansour, Alexandre, Porto, Alizée, Flécher, Erwan, Esvan, Maxime, Fougerou, Claire, Fillâtre, Pierre, Duburcq, Thibault, Lebreton, Guillaume, Para, Marylou, Stephan, François, Hraiech, Sami, Ross, James T., Schmidt, Matthieu, Vincentelli, André, and Nesseler, Nicolas

Subjects
*SARS-CoV-2, *PATIENT positioning, *EXTRACORPOREAL membrane oxygenation, *REVERSE transcriptase polymerase chain reaction, *COVID-19
Abstract

OBJECTIVES: Prone positioning and venovenous extracorporeal membrane oxygenation (ECMO) are both useful interventions in acute respiratory distress syndrome (ARDS). Combining the two therapies is feasible and safe, but the effectiveness is not known. Our objective was to evaluate the potential survival benefit of prone positioning in venovenous ECMO patients cannulated for COVID-19–related ARDS. DESIGN: Retrospective analysis of a multicenter cohort. PATIENTS: Patients on venovenous ECMO who tested positive for severe acute respiratory syndrome coronavirus 2 by reverse transcriptase polymerase chain reaction or with a diagnosis on chest CT were eligible. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: All patients on venovenous ECMO for respiratory failure in whom prone position status while on ECMO and in-hospital mortality were known were included. Of 647 patients in 41 centers, 517 were included. Median age was 55 (47–61), 78% were male and 95% were proned before cannulation. After cannulation, 364 patients (70%) were proned and 153 (30%) remained in the supine position for the whole ECMO run. There were 194 (53%) and 92 (60%) deaths in the prone and the supine groups, respectively. Prone position on ECMO was independently associated with lower in-hospital mortality (odds ratio = 0.49 [0.29–0.84]; p = 0.010). In 153 propensity score-matched pairs, mortality rate was 49.7% in the prone position group versus 60.1% in the supine position group (p = 0.085). Considering only patients alive at decannulation, propensity-matched proned patients had a significantly lower mortality rate (22.4% vs 37.8%; p = 0.029) than nonproned patients. CONCLUSIONS: Prone position may be beneficial in patients supported by venovenous ECMO for COVID-19–related ARDS but more data are needed to draw definitive conclusions. [ABSTRACT FROM AUTHOR]

Published
2023
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6. Timing of Prone Positioning During Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome.

Author

Giani, Marco, Rezoagli, Emanuele, Guervilly, Christophe, Rilinger, Jonathan, Duburcq, Thibault, Petit, Matthieu, Textoris, Laura, Garcia, Bruno, Wengenmayer, Tobias, Bellani, Giacomo, Grasselli, Giacomo, Pesenti, Antonio, Combes, Alain, Foti, Giuseppe, Schmidt, Matthieu, Lucchini, Alberto, Fumagalli, Benedetta, Martucci, Gennaro, Arcadipane, Antonio, and Garofalo, Eugenio

Published
2023
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