1. Evaluation of patch test reactions by evaporimetry and colorimetry.
- Author
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Brusi, C., Giorgini, S., Francalanci, S., Gola, M., and Sertoli, A.
- Subjects
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CONTACT dermatitis , *COLORIMETRY , *MEASUREMENT , *EVALUATION , *CLINICAL trials , *MEDICAL research , *SKIN inflammation - Abstract
The article presents information on evaluation of patch test reactions by evaporimetry and colorimetry. For calorimetry as well as for evaporimetry, extreme individual variability in the cutaneous response, was found. This does not allow the use in clinical practice of either method when only 1 measurement is performed at a particular time, for example at 2 or at 3 days. Only double measurement, for example after 2 and 3 days, following the time course of individual values, can give further information about specific reactions. With this proviso, these results justify the utilization of such methods in diagnostic patch tests and, above all, in the evaluation, in experimental contact dermatitis, of reactions provoked by new haptens, concentrations and vehicles.
- Published
- 1994
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